Non-bioabsorbable vs. bioabsorbable membrane

assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review.

Lawrence C. Parrish, Takanari Miyamoto, Nelson Fong, John S. Mattson, D. Roselyn Cerutis

Research output: Contribution to journalReview article

38 Citations (Scopus)

Abstract

In a 1998 review article, Laurell and colleagues performed a meta-analysis of relevant guided tissue regeneration (GTR) articles over the previous 20 years (1). The purpose of the present research was to expand on that work, particularly searching for trends discriminating between bioabsorbable and non-bioabsorbable barriers, as well as the use of enamel matrix derivative, with respect to interproximal bony defects. The most recent periodontal journals were reviewed and a search of PubMed (National Institutes of Health) was conducted via the internet covering 1990 to the present. Forty-nine articles were found to be relevant and within established parameters. The data were analyzed using (a) a variation of the methods described in Laurell et al. (1) and (b) statistics appropriate for inter-group comparisons. In most respects, all membranes and enamel matrix derivative (EMD) delivered better outcomes, in the range of 1 to 2 mm, than open flap debridement. The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level (CAL) gain than any open flap configuration. Other than collagen without grafts versus non-bioabsorbables without grafts, no other comparison between membranes or between membranes and EMD found any significant differences (P > 0.05). GTR was confirmed to be superior to open flap debridement.

Original languageEnglish
Pages (from-to)383-400
Number of pages18
JournalJournal of oral science
Volume51
Issue number3
StatePublished - Sep 2009

Fingerprint

Guided Tissue Regeneration
Dental Enamel
Membranes
Debridement
Transplants
National Institutes of Health (U.S.)
PubMed
Internet
Meta-Analysis
Collagen
Research

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Non-bioabsorbable vs. bioabsorbable membrane : assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review. / Parrish, Lawrence C.; Miyamoto, Takanari; Fong, Nelson; Mattson, John S.; Cerutis, D. Roselyn.

In: Journal of oral science, Vol. 51, No. 3, 09.2009, p. 383-400.

Research output: Contribution to journalReview article

@article{8c54f75a569f4695a8078faf0bd26b52,
title = "Non-bioabsorbable vs. bioabsorbable membrane: assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review.",
abstract = "In a 1998 review article, Laurell and colleagues performed a meta-analysis of relevant guided tissue regeneration (GTR) articles over the previous 20 years (1). The purpose of the present research was to expand on that work, particularly searching for trends discriminating between bioabsorbable and non-bioabsorbable barriers, as well as the use of enamel matrix derivative, with respect to interproximal bony defects. The most recent periodontal journals were reviewed and a search of PubMed (National Institutes of Health) was conducted via the internet covering 1990 to the present. Forty-nine articles were found to be relevant and within established parameters. The data were analyzed using (a) a variation of the methods described in Laurell et al. (1) and (b) statistics appropriate for inter-group comparisons. In most respects, all membranes and enamel matrix derivative (EMD) delivered better outcomes, in the range of 1 to 2 mm, than open flap debridement. The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level (CAL) gain than any open flap configuration. Other than collagen without grafts versus non-bioabsorbables without grafts, no other comparison between membranes or between membranes and EMD found any significant differences (P > 0.05). GTR was confirmed to be superior to open flap debridement.",
author = "Parrish, {Lawrence C.} and Takanari Miyamoto and Nelson Fong and Mattson, {John S.} and Cerutis, {D. Roselyn}",
year = "2009",
month = "9",
language = "English",
volume = "51",
pages = "383--400",
journal = "Journal of oral science",
issn = "1343-4934",
publisher = "Nihon University",
number = "3",

}

TY - JOUR

T1 - Non-bioabsorbable vs. bioabsorbable membrane

T2 - assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review.

AU - Parrish, Lawrence C.

AU - Miyamoto, Takanari

AU - Fong, Nelson

AU - Mattson, John S.

AU - Cerutis, D. Roselyn

PY - 2009/9

Y1 - 2009/9

N2 - In a 1998 review article, Laurell and colleagues performed a meta-analysis of relevant guided tissue regeneration (GTR) articles over the previous 20 years (1). The purpose of the present research was to expand on that work, particularly searching for trends discriminating between bioabsorbable and non-bioabsorbable barriers, as well as the use of enamel matrix derivative, with respect to interproximal bony defects. The most recent periodontal journals were reviewed and a search of PubMed (National Institutes of Health) was conducted via the internet covering 1990 to the present. Forty-nine articles were found to be relevant and within established parameters. The data were analyzed using (a) a variation of the methods described in Laurell et al. (1) and (b) statistics appropriate for inter-group comparisons. In most respects, all membranes and enamel matrix derivative (EMD) delivered better outcomes, in the range of 1 to 2 mm, than open flap debridement. The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level (CAL) gain than any open flap configuration. Other than collagen without grafts versus non-bioabsorbables without grafts, no other comparison between membranes or between membranes and EMD found any significant differences (P > 0.05). GTR was confirmed to be superior to open flap debridement.

AB - In a 1998 review article, Laurell and colleagues performed a meta-analysis of relevant guided tissue regeneration (GTR) articles over the previous 20 years (1). The purpose of the present research was to expand on that work, particularly searching for trends discriminating between bioabsorbable and non-bioabsorbable barriers, as well as the use of enamel matrix derivative, with respect to interproximal bony defects. The most recent periodontal journals were reviewed and a search of PubMed (National Institutes of Health) was conducted via the internet covering 1990 to the present. Forty-nine articles were found to be relevant and within established parameters. The data were analyzed using (a) a variation of the methods described in Laurell et al. (1) and (b) statistics appropriate for inter-group comparisons. In most respects, all membranes and enamel matrix derivative (EMD) delivered better outcomes, in the range of 1 to 2 mm, than open flap debridement. The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level (CAL) gain than any open flap configuration. Other than collagen without grafts versus non-bioabsorbables without grafts, no other comparison between membranes or between membranes and EMD found any significant differences (P > 0.05). GTR was confirmed to be superior to open flap debridement.

UR - http://www.scopus.com/inward/record.url?scp=74049146353&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74049146353&partnerID=8YFLogxK

M3 - Review article

VL - 51

SP - 383

EP - 400

JO - Journal of oral science

JF - Journal of oral science

SN - 1343-4934

IS - 3

ER -