Abstract
Natural and artificial ribozymes can catalyse a diverse range of chemical reactions. Through recent efforts in enzyme engineering, it has become possible to tailor the activity of ribozymes to respond allosterically to specific effector compounds. These allosteric ribozymes function as effector-dependent molecular switches that could find application as novel genetic-control elements, biosensor components or precision switches for use in nanotechnology. Copyright (C) 1999 Elsevier Science Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 469-476 |
| Number of pages | 8 |
| Journal | Trends in Biotechnology |
| Volume | 17 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 1999 |
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All Science Journal Classification (ASJC) codes
- Bioengineering
Cite this
Nucleic acid molecular switches. / Soukup, Garrett; Breaker, Ronald R.
In: Trends in Biotechnology, Vol. 17, No. 12, 01.12.1999, p. 469-476.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nucleic acid molecular switches
AU - Soukup, Garrett
AU - Breaker, Ronald R.
PY - 1999/12/1
Y1 - 1999/12/1
N2 - Natural and artificial ribozymes can catalyse a diverse range of chemical reactions. Through recent efforts in enzyme engineering, it has become possible to tailor the activity of ribozymes to respond allosterically to specific effector compounds. These allosteric ribozymes function as effector-dependent molecular switches that could find application as novel genetic-control elements, biosensor components or precision switches for use in nanotechnology. Copyright (C) 1999 Elsevier Science Ltd.
AB - Natural and artificial ribozymes can catalyse a diverse range of chemical reactions. Through recent efforts in enzyme engineering, it has become possible to tailor the activity of ribozymes to respond allosterically to specific effector compounds. These allosteric ribozymes function as effector-dependent molecular switches that could find application as novel genetic-control elements, biosensor components or precision switches for use in nanotechnology. Copyright (C) 1999 Elsevier Science Ltd.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033485863&partnerID=8YFLogxK
U2 - 10.1016/S0167-7799(99)01383-9
DO - 10.1016/S0167-7799(99)01383-9
M3 - Article
C2 - 10557159
AN - SCOPUS:0033485863
VL - 17
SP - 469
EP - 476
JO - Trends in Biotechnology
JF - Trends in Biotechnology
SN - 0167-7799
IS - 12
ER -