Nucleic acid molecular switches

Garrett Soukup, Ronald R. Breaker

Research output: Contribution to journalArticle

120 Citations (Scopus)

Abstract

Natural and artificial ribozymes can catalyse a diverse range of chemical reactions. Through recent efforts in enzyme engineering, it has become possible to tailor the activity of ribozymes to respond allosterically to specific effector compounds. These allosteric ribozymes function as effector-dependent molecular switches that could find application as novel genetic-control elements, biosensor components or precision switches for use in nanotechnology. Copyright (C) 1999 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)469-476
Number of pages8
JournalTrends in Biotechnology
Volume17
Issue number12
DOIs
StatePublished - Dec 1 1999

Fingerprint

Catalytic RNA
Nucleic acids
Nucleic Acids
Switches
Nanotechnology
Biosensing Techniques
Biosensors
Chemical reactions
Enzymes

All Science Journal Classification (ASJC) codes

  • Bioengineering

Cite this

Nucleic acid molecular switches. / Soukup, Garrett; Breaker, Ronald R.

In: Trends in Biotechnology, Vol. 17, No. 12, 01.12.1999, p. 469-476.

Research output: Contribution to journalArticle

Soukup, Garrett ; Breaker, Ronald R. / Nucleic acid molecular switches. In: Trends in Biotechnology. 1999 ; Vol. 17, No. 12. pp. 469-476.
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