Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy: A case control study

Rajashekar R. Gurrala; Venkata M.B. Alla; Wilbert S. Aronow; Jai S. Shankar; Meena K. Angamutta; Krishna S.R. Lanka; Sundaram Challa; Chandra K. Nair

doi:10.1055/s-0031-1278268

Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy: A case control study

Rajashekar R. Gurrala, Venkata M.B. Alla, Wilbert S. Aronow, Jai S. Shankar, Meena K. Angamutta, Krishna S.R. Lanka, Sundaram Challa, Chandra K. Nair

Department of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The myocardial performance index (MPI) was assessed in 30 patients with limb girdle muscle dystrophy (LGMD) with a normal left ventricular ejection fraction (greater than 50%), as well as in 30 age-and sex-matched healthy adults with a left ventricular ejection fraction greater than 50%. MPIs derived by pulsed-wave Doppler and tissue Doppler were also compared. The MPI was 0.37±0.09 in the LGMD patients and 0.29±0.09 in the control group (P=0.003). These data show that patients with LGMD have occult cardiac dysfunction as evidenced by a higher MPI than the controls. There was good agreement between the MPIs measured by pulsed-wave Doppler and tissue Doppler methods in these patients.

Original language	English (US)
Pages (from-to)	139-142
Number of pages	4
Journal	International Journal of Angiology
Volume	16
Issue number	4
DOIs	https://doi.org/10.1055/s-0031-1278268
State	Published - Sep 2007

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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10.1055/s-0031-1278268

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title = "Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy: A case control study",

abstract = "The myocardial performance index (MPI) was assessed in 30 patients with limb girdle muscle dystrophy (LGMD) with a normal left ventricular ejection fraction (greater than 50%), as well as in 30 age-and sex-matched healthy adults with a left ventricular ejection fraction greater than 50%. MPIs derived by pulsed-wave Doppler and tissue Doppler were also compared. The MPI was 0.37±0.09 in the LGMD patients and 0.29±0.09 in the control group (P=0.003). These data show that patients with LGMD have occult cardiac dysfunction as evidenced by a higher MPI than the controls. There was good agreement between the MPIs measured by pulsed-wave Doppler and tissue Doppler methods in these patients.",

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AU - Gurrala, Rajashekar R.

AU - Alla, Venkata M.B.

AU - Aronow, Wilbert S.

AU - Shankar, Jai S.

AU - Angamutta, Meena K.

AU - Lanka, Krishna S.R.

AU - Challa, Sundaram

AU - Nair, Chandra K.

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AB - The myocardial performance index (MPI) was assessed in 30 patients with limb girdle muscle dystrophy (LGMD) with a normal left ventricular ejection fraction (greater than 50%), as well as in 30 age-and sex-matched healthy adults with a left ventricular ejection fraction greater than 50%. MPIs derived by pulsed-wave Doppler and tissue Doppler were also compared. The MPI was 0.37±0.09 in the LGMD patients and 0.29±0.09 in the control group (P=0.003). These data show that patients with LGMD have occult cardiac dysfunction as evidenced by a higher MPI than the controls. There was good agreement between the MPIs measured by pulsed-wave Doppler and tissue Doppler methods in these patients.

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Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy: A case control study

Abstract

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