Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy: A case control study

Rajashekar R. Gurrala, Venkata (Mahesh) Alla, Wilbert S. Aronow, Jai S. Shankar, Meena K. Angamutta, Krishna S R Lanka, Sundaram Challa, Chandra K. Nair

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The myocardial performance index (MPI) was assessed in 30 patients with limb girdle muscle dystrophy (LGMD) with a normal left ventricular ejection fraction (greater than 50%), as well as in 30 age-and sex-matched healthy adults with a left ventricular ejection fraction greater than 50%. MPIs derived by pulsed-wave Doppler and tissue Doppler were also compared. The MPI was 0.37±0.09 in the LGMD patients and 0.29±0.09 in the control group (P=0.003). These data show that patients with LGMD have occult cardiac dysfunction as evidenced by a higher MPI than the controls. There was good agreement between the MPIs measured by pulsed-wave Doppler and tissue Doppler methods in these patients.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalInternational Journal of Angiology
Volume16
Issue number4
DOIs
StatePublished - Sep 2007

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Left Ventricular Dysfunction
Case-Control Studies
Extremities
Muscles
Stroke Volume
Control Groups

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy : A case control study. / Gurrala, Rajashekar R.; Alla, Venkata (Mahesh); Aronow, Wilbert S.; Shankar, Jai S.; Angamutta, Meena K.; Lanka, Krishna S R; Challa, Sundaram; Nair, Chandra K.

In: International Journal of Angiology, Vol. 16, No. 4, 09.2007, p. 139-142.

Research output: Contribution to journalArticle

Gurrala, Rajashekar R. ; Alla, Venkata (Mahesh) ; Aronow, Wilbert S. ; Shankar, Jai S. ; Angamutta, Meena K. ; Lanka, Krishna S R ; Challa, Sundaram ; Nair, Chandra K. / Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy : A case control study. In: International Journal of Angiology. 2007 ; Vol. 16, No. 4. pp. 139-142.
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