Occurrence of Z-band widening in human atrial cells

G. Côté, Syed M. Mohiuddin, P. E. Roy

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Fifty-four biopsies of human auricular appendages have been studied under the electron microscope. In 24% of the cases, various degrees of broadening of the Z-lines were observed. There was a relation between the changes of the Z-line, the age of the patient, and the surgical diagnosis. The structures observed in the Z-disc had a diameter corresponding to that of the I-band filaments and appeared to be in continuity with them. These periodic structures were oriented parallel to the long axis of the fiber, but in one case they were oblique. The reported anomalies of the Z-line do not correspond exactly to those previously described in cats and dogs, nor to the rods of the "nemaline myopathy." The present findings cannot be explained by the existing theories on the structural organization of the Z-line.

Original languageEnglish
Pages (from-to)307-318
Number of pages12
JournalExperimental and Molecular Pathology
Volume13
Issue number3
DOIs
StatePublished - 1970
Externally publishedYes

Fingerprint

Nemaline Myopathies
Biopsy
Periodic structures
Electron microscopes
Atrial Appendage
Fibers
Cats
Dogs
Electrons

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry
  • Molecular Biology
  • Pathology and Forensic Medicine

Cite this

Occurrence of Z-band widening in human atrial cells. / Côté, G.; Mohiuddin, Syed M.; Roy, P. E.

In: Experimental and Molecular Pathology, Vol. 13, No. 3, 1970, p. 307-318.

Research output: Contribution to journalArticle

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