Ocular autonomic physiology and pharmacology

Marshalyn G. McKoy, Ya Fatou Njie-Mbye, Catherine A. Opere

Research output: Chapter in Book/Report/Conference proceedingChapter


Most structures of the eye receive dual innervation from the parasympathetic and sympathetic divisions of the autonomic nervous system. The effects of the parasympathetic and sympathetic systems on ocular function are mainly antagonistic. These effects may arise from each division of the autonomic nervous system innervating the same tissue or different tissues in the eye to produce contrasting physiologic responses. An example is the autonomic control of pupillary diameter. The sphincter pupillae is innervated mainly by parasympathetic neurons, while the dilator pupillae is innervated mainly by sympathetic neurons. Parasympathetic stimulation contracts the sphincter pupillae to cause miosis, whereas sympathetic stimulation contracts the dilator pupillae to produce mydriasis.

Original languageEnglish (US)
Title of host publicationHandbook of Basic and Clinical Ocular Pharmacology and Therapeutics
Number of pages12
ISBN (Electronic)9780128192917
ISBN (Print)9780128192924
StatePublished - Jan 1 2022

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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