Ocular side effects of drugs administered systemically for treatment of nonocular diseases

Dariush Yalzadeh, Anthonia Okolie, Fatima Muili, Ya Fatou Njie-Mbye, Catherine A. Opere, Odochi Ohia-Nwoko, Sunny E. Ohia

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Although the eye consists of barriers that isolated some of its structures from general blood circulation, this system is still vulnerable to side effects of drugs administered for the treatment of diseases affecting nonocular organs such as the cardiovascular and central nervous systems (CNS). The toxicities produced by drugs used for the treatment of nonocular diseases may have profound effect on ocular tissues such as the cornea, lens, and retina. Consequently, it is important for the clinical practitioner and students of the eye to be aware that their patients that are treated for nonocular diseases may be taking medications that could produce ocular side effects. These side effects could also be compounded by the fact that drugs that are administered for the treatment of eye diseases also have the potential to cause ocular side effects. Although the primary focus of this chapter is to summarize the ocular side effects of a wide variety of drug classes used for the treatment of nonocular diseases, we have also discussed the side effects of drugs used for the treatment of some ocular disorders.

Original languageEnglish (US)
Title of host publicationHandbook of Basic and Clinical Ocular Pharmacology and Therapeutics
PublisherElsevier
Pages491-507
Number of pages17
ISBN (Electronic)9780128192917
ISBN (Print)9780128192924
DOIs
StatePublished - Jan 1 2022

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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