TY - JOUR
T1 - Open mesh versus non-mesh repair of groin hernia meta-analysis of randomized trials leased on individual patient data
T2 - The EU Hernia Trialists Collaboration
AU - The EU Hernia Trialists Collaboration
AU - Coala Trial Steering Committee
AU - Grant, A. M.
AU - Fingerhut, A.
AU - Go, P.
AU - Grant, A.
AU - Kingsnorth, A.
AU - Merello, J.
AU - O’dwyer, P.
AU - Payne, J.
AU - Grant, A.
AU - McCormack, K.
AU - Ross, S.
AU - Scott, N.
AU - Vale, L.
AU - Aitola, P.
AU - Anderberg, B.
AU - Arvidsson, D.
AU - Barkun, J.
AU - Barth, R.
AU - Bay-Nielsen, M.
AU - Beets, G.
AU - Bittner, R.
AU - Bringman, S.
AU - Callesen, T.
AU - Castoro, C.
AU - Dirksen, C.
AU - Filipi, C.
AU - Fitzgibbons, R.
AU - Friis, E.
AU - Gir à O, R.
AU - Graham, P.
AU - Hatzitheoklitos, E.
AU - Hauters, P.
AU - Heikkinen, T.
AU - Jeekel, H.
AU - Johansson, B.
AU - Juul, P.
AU - Kald, A.
AU - Kehlet, H.
AU - Khoury, N.
AU - Klingler, A.
AU - K Ö Ninger, J.
AU - Kozol, R.
AU - Leibl, B.
AU - Macintyre, I.
AU - Maddern, G.
AU - McGillicuddy, J.
AU - Millat, B.
AU - Nilsson, E.
AU - Nordin, P.
AU - Paganini, A.
PY - 2002/9/1
Y1 - 2002/9/1
N2 - Background. The EU Hernia Trialists Collaboration was established to provide reliable evaluation of newer methods of groin hernia repair. It involved 70 investigators in 20 countries. Materials and methods. Twenty eligible trials (5016 participants) of open mesh vs. non-mesh groin hernia repair were identified. Meta-analysis was performed using raw individual patient data where possible. Results. Fewer hernia recurrences were reported after mesh repair. There were no clear differences between mesh and non-mesh groups in complications. Overall, those in the mesh groups had a shorter hospital stay, quicker return to usual activities and less frequent persisting pain, but individual trial results varied. Conclusions. The review provides strong evidence that open mesh repair is associated with a reduction in the risk of recurrence of between 50% and 75%. There is also some evidence of quicker recovery and of lower rates of persisting pain following open mesh repair.
AB - Background. The EU Hernia Trialists Collaboration was established to provide reliable evaluation of newer methods of groin hernia repair. It involved 70 investigators in 20 countries. Materials and methods. Twenty eligible trials (5016 participants) of open mesh vs. non-mesh groin hernia repair were identified. Meta-analysis was performed using raw individual patient data where possible. Results. Fewer hernia recurrences were reported after mesh repair. There were no clear differences between mesh and non-mesh groups in complications. Overall, those in the mesh groups had a shorter hospital stay, quicker return to usual activities and less frequent persisting pain, but individual trial results varied. Conclusions. The review provides strong evidence that open mesh repair is associated with a reduction in the risk of recurrence of between 50% and 75%. There is also some evidence of quicker recovery and of lower rates of persisting pain following open mesh repair.
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U2 - 10.1007/s10029-002-0073-1
DO - 10.1007/s10029-002-0073-1
M3 - Article
C2 - 12209302
AN - SCOPUS:0036737334
VL - 6
SP - 130
EP - 136
JO - Hernia : the journal of hernias and abdominal wall surgery
JF - Hernia : the journal of hernias and abdominal wall surgery
SN - 1265-4906
IS - 3
ER -