Patient perceptions of a proton pump inhibitor therapeutic interchange program across the continuum of care

Michelle M. Sodorff, Kimberly A. Galt, Michael A. Galt, Paul D. Turner, Jason E. Lambrecht

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective. To determine if participation in a hospital-based proton pump inhibitor (PPI) therapeutic interchange program resulted in differences in patient perceptions related to clinical and humanistic outcomes. Methods. A quasiexperimental repeated-measures study compared patients' perceptions in two groups (111 patients) at hospital admission, discharge, 3-4 days after discharge, and 2-3 weeks after discharge to detect differences across the continuum of care. Patient awareness of the hospital- based interchange also was examined. Clinical and quality-of-life outcomes were measured by using a condition-specific instrument modified for use with patients. Satisfaction and expectations were measured by using extent-of-agreement measures. Group 1 (60 patients) was prescribed omeprazole before admission, switched to lansoprazole during hospitalization, and discharged taking omeprazole. Group 2 (51 patients) was prescribed lansoprazole before admission and continued taking lansoprazole throughout hospitalization and after discharge. Patients who were unable to communicate or who had a substantial change in severity of illness (not attributable to gastrointestinal disorders) during the study were excluded. Results. No significant differences were found between groups 1 and 2 for clinical outcomes, quality of life, extent to which expectations were met, or satisfaction at the four time periods. Nineteen (36%) of 53 surveyed patients in group 1 were not aware that their therapy had been interchanged while in the hospital. Conclusion. Patient-perceived outcomes and expectations of therapy across the continuum of care were not affected by a hospital-based PPI therapeutic interchange program.

Original languageEnglish
Pages (from-to)500-512
Number of pages13
JournalPharmacotherapy
Volume22
Issue number4
StatePublished - 2002

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Continuity of Patient Care
Proton Pump Inhibitors
Lansoprazole
Therapeutics
Omeprazole
Hospitalization
Quality of Life

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Sodorff, M. M., Galt, K. A., Galt, M. A., Turner, P. D., & Lambrecht, J. E. (2002). Patient perceptions of a proton pump inhibitor therapeutic interchange program across the continuum of care. Pharmacotherapy, 22(4), 500-512.

Patient perceptions of a proton pump inhibitor therapeutic interchange program across the continuum of care. / Sodorff, Michelle M.; Galt, Kimberly A.; Galt, Michael A.; Turner, Paul D.; Lambrecht, Jason E.

In: Pharmacotherapy, Vol. 22, No. 4, 2002, p. 500-512.

Research output: Contribution to journalArticle

Sodorff, MM, Galt, KA, Galt, MA, Turner, PD & Lambrecht, JE 2002, 'Patient perceptions of a proton pump inhibitor therapeutic interchange program across the continuum of care', Pharmacotherapy, vol. 22, no. 4, pp. 500-512.
Sodorff, Michelle M. ; Galt, Kimberly A. ; Galt, Michael A. ; Turner, Paul D. ; Lambrecht, Jason E. / Patient perceptions of a proton pump inhibitor therapeutic interchange program across the continuum of care. In: Pharmacotherapy. 2002 ; Vol. 22, No. 4. pp. 500-512.
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abstract = "Objective. To determine if participation in a hospital-based proton pump inhibitor (PPI) therapeutic interchange program resulted in differences in patient perceptions related to clinical and humanistic outcomes. Methods. A quasiexperimental repeated-measures study compared patients' perceptions in two groups (111 patients) at hospital admission, discharge, 3-4 days after discharge, and 2-3 weeks after discharge to detect differences across the continuum of care. Patient awareness of the hospital- based interchange also was examined. Clinical and quality-of-life outcomes were measured by using a condition-specific instrument modified for use with patients. Satisfaction and expectations were measured by using extent-of-agreement measures. Group 1 (60 patients) was prescribed omeprazole before admission, switched to lansoprazole during hospitalization, and discharged taking omeprazole. Group 2 (51 patients) was prescribed lansoprazole before admission and continued taking lansoprazole throughout hospitalization and after discharge. Patients who were unable to communicate or who had a substantial change in severity of illness (not attributable to gastrointestinal disorders) during the study were excluded. Results. No significant differences were found between groups 1 and 2 for clinical outcomes, quality of life, extent to which expectations were met, or satisfaction at the four time periods. Nineteen (36{\%}) of 53 surveyed patients in group 1 were not aware that their therapy had been interchanged while in the hospital. Conclusion. Patient-perceived outcomes and expectations of therapy across the continuum of care were not affected by a hospital-based PPI therapeutic interchange program.",
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