Perforating Granuloma Annulare in a Patient With Acquired Immunodeficiency Syndrome

Immunohistologic Evaluation of the Cellular Infiltrate

Christopher Huerter, Jonathan Bass, Wilma F. Bergfeld, Raymond R. Tubbs

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The inflammatory infiltrate found in the lesions of perforating granuloma annulare in a patient with acquired immunodeficiency syndrome was analyzed. Double labeling with fluorescent antibody tags fluorescein isothiocyanate—Leu 4 (peripheral T cells) and phycoerythrin-Leu 2a (cytotoxic/suppressor) revealed the infiltrate to consist predominantly of cytotoxic/suppressor T cells. This finding is a reflection of the patient's altered immune status and calls into question the role of specific T-cell subsets in the pathogenesis of granuloma annulare. (Arch Dermatol 1987;123:1217-1220).

Original languageEnglish
Pages (from-to)1217-1220
Number of pages4
JournalArchives of Dermatology
Volume123
Issue number9
DOIs
StatePublished - 1987
Externally publishedYes

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Granuloma Annulare
Acquired Immunodeficiency Syndrome
Phycoerythrin
T-Lymphocytes
T-Lymphocyte Subsets
Fluorescein
Antibodies

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Perforating Granuloma Annulare in a Patient With Acquired Immunodeficiency Syndrome : Immunohistologic Evaluation of the Cellular Infiltrate. / Huerter, Christopher; Bass, Jonathan; Bergfeld, Wilma F.; Tubbs, Raymond R.

In: Archives of Dermatology, Vol. 123, No. 9, 1987, p. 1217-1220.

Research output: Contribution to journalArticle

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