Perforating Granuloma Annulare in a Patient With Acquired Immunodeficiency Syndrome: Immunohistologic Evaluation of the Cellular Infiltrate

Christopher J. Huerter, Jonathan Bass, Wilma F. Bergfeld, Raymond R. Tubbs

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

The inflammatory infiltrate found in the lesions of perforating granuloma annulare in a patient with acquired immunodeficiency syndrome was analyzed. Double labeling with fluorescent antibody tags fluorescein isothiocyanate—Leu 4 (peripheral T cells) and phycoerythrin-Leu 2a (cytotoxic/suppressor) revealed the infiltrate to consist predominantly of cytotoxic/suppressor T cells. This finding is a reflection of the patient's altered immune status and calls into question the role of specific T-cell subsets in the pathogenesis of granuloma annulare. (Arch Dermatol 1987;123:1217-1220).

Original languageEnglish (US)
Pages (from-to)1217-1220
Number of pages4
JournalArchives of Dermatology
Volume123
Issue number9
DOIs
StatePublished - Sep 1987
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Dermatology

Fingerprint Dive into the research topics of 'Perforating Granuloma Annulare in a Patient With Acquired Immunodeficiency Syndrome: Immunohistologic Evaluation of the Cellular Infiltrate'. Together they form a unique fingerprint.

  • Cite this