Abstract
The inflammatory infiltrate found in the lesions of perforating granuloma annulare in a patient with acquired immunodeficiency syndrome was analyzed. Double labeling with fluorescent antibody tags fluorescein isothiocyanate—Leu 4 (peripheral T cells) and phycoerythrin-Leu 2a (cytotoxic/suppressor) revealed the infiltrate to consist predominantly of cytotoxic/suppressor T cells. This finding is a reflection of the patient's altered immune status and calls into question the role of specific T-cell subsets in the pathogenesis of granuloma annulare. (Arch Dermatol 1987;123:1217-1220).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1217-1220 |
| Number of pages | 4 |
| Journal | Archives of Dermatology |
| Volume | 123 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1987 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Dermatology
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Cite this
Huerter, C. J., Bass, J., Bergfeld, W. F., & Tubbs, R. R. (1987). Perforating Granuloma Annulare in a Patient With Acquired Immunodeficiency Syndrome: Immunohistologic Evaluation of the Cellular Infiltrate. Archives of Dermatology, 123(9), 1217-1220. https://doi.org/10.1001/archderm.1987.01660330128025