Pharmacists can help prevent lipoid pneumonia

Two case reports

Ann E. Cabri, Afoma King, Lee E. Morrow, Mark A. Malesker

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives To report 2 cases of lipoid pneumonia. Summary Lipoid pneumonia is an inflammatory process in the lower airways due to the presence of lipid molecules in the alveoli. Exogenous lipoid pneumonia is due to the inhalation or aspiration of fat-containing substances. Historically, mineral oil is the most common medication cause but there have also been several reports of lipoid pneumonia associated with petroleum jelly, medicated vapor rub, and lip glosses. Two case reports are presented to illustrate the importance of identifying risk factors for lipoid pneumonia. Results Use of the Naranjo algorithm suggested that both cases of lipoid pneumonia were “possibly” due to aspiration of lipid-containing over-the-counter agents. The first case was associated with aspiration of mentholated topical ointment applied intranasally, whereas the second case was attributed to probable aspiration of mineral oil for management of chronic constipation. Conclusion Pharmacists in many practice settings can play an integral role in preventing this condition and screening for patients who may warrant a diagnostic workup. During medication reconciliation, pharmacists should identify all prescription and nonprescription medications used by patients. Patients should specifically be asked about lipid-based over-the-counter products and cosmetic agents.

Original languageEnglish (US)
Pages (from-to)616-618
Number of pages3
JournalJournal of the American Pharmacists Association
Volume57
Issue number5
DOIs
StatePublished - Sep 1 2017

Fingerprint

Pharmacists
Mineral Oil
Pneumonia
Lipids
Petrolatum
Cosmetics
Ointments
Screening
Medication Reconciliation
Fats
Vapors
Molecules
Constipation
Lip
Inhalation
Prescriptions

All Science Journal Classification (ASJC) codes

  • Pharmacology (nursing)
  • Pharmacy
  • Pharmacology

Cite this

Pharmacists can help prevent lipoid pneumonia : Two case reports. / Cabri, Ann E.; King, Afoma; Morrow, Lee E.; Malesker, Mark A.

In: Journal of the American Pharmacists Association, Vol. 57, No. 5, 01.09.2017, p. 616-618.

Research output: Contribution to journalArticle

@article{18bcf998465d474799c4586e00821823,
title = "Pharmacists can help prevent lipoid pneumonia: Two case reports",
abstract = "Objectives To report 2 cases of lipoid pneumonia. Summary Lipoid pneumonia is an inflammatory process in the lower airways due to the presence of lipid molecules in the alveoli. Exogenous lipoid pneumonia is due to the inhalation or aspiration of fat-containing substances. Historically, mineral oil is the most common medication cause but there have also been several reports of lipoid pneumonia associated with petroleum jelly, medicated vapor rub, and lip glosses. Two case reports are presented to illustrate the importance of identifying risk factors for lipoid pneumonia. Results Use of the Naranjo algorithm suggested that both cases of lipoid pneumonia were “possibly” due to aspiration of lipid-containing over-the-counter agents. The first case was associated with aspiration of mentholated topical ointment applied intranasally, whereas the second case was attributed to probable aspiration of mineral oil for management of chronic constipation. Conclusion Pharmacists in many practice settings can play an integral role in preventing this condition and screening for patients who may warrant a diagnostic workup. During medication reconciliation, pharmacists should identify all prescription and nonprescription medications used by patients. Patients should specifically be asked about lipid-based over-the-counter products and cosmetic agents.",
author = "Cabri, {Ann E.} and Afoma King and Morrow, {Lee E.} and Malesker, {Mark A.}",
year = "2017",
month = "9",
day = "1",
doi = "10.1016/j.japh.2017.05.012",
language = "English (US)",
volume = "57",
pages = "616--618",
journal = "Journal of the American Pharmacists Association : JAPhA",
issn = "1544-3191",
publisher = "American Pharmacists Association",
number = "5",

}

TY - JOUR

T1 - Pharmacists can help prevent lipoid pneumonia

T2 - Two case reports

AU - Cabri, Ann E.

AU - King, Afoma

AU - Morrow, Lee E.

AU - Malesker, Mark A.

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Objectives To report 2 cases of lipoid pneumonia. Summary Lipoid pneumonia is an inflammatory process in the lower airways due to the presence of lipid molecules in the alveoli. Exogenous lipoid pneumonia is due to the inhalation or aspiration of fat-containing substances. Historically, mineral oil is the most common medication cause but there have also been several reports of lipoid pneumonia associated with petroleum jelly, medicated vapor rub, and lip glosses. Two case reports are presented to illustrate the importance of identifying risk factors for lipoid pneumonia. Results Use of the Naranjo algorithm suggested that both cases of lipoid pneumonia were “possibly” due to aspiration of lipid-containing over-the-counter agents. The first case was associated with aspiration of mentholated topical ointment applied intranasally, whereas the second case was attributed to probable aspiration of mineral oil for management of chronic constipation. Conclusion Pharmacists in many practice settings can play an integral role in preventing this condition and screening for patients who may warrant a diagnostic workup. During medication reconciliation, pharmacists should identify all prescription and nonprescription medications used by patients. Patients should specifically be asked about lipid-based over-the-counter products and cosmetic agents.

AB - Objectives To report 2 cases of lipoid pneumonia. Summary Lipoid pneumonia is an inflammatory process in the lower airways due to the presence of lipid molecules in the alveoli. Exogenous lipoid pneumonia is due to the inhalation or aspiration of fat-containing substances. Historically, mineral oil is the most common medication cause but there have also been several reports of lipoid pneumonia associated with petroleum jelly, medicated vapor rub, and lip glosses. Two case reports are presented to illustrate the importance of identifying risk factors for lipoid pneumonia. Results Use of the Naranjo algorithm suggested that both cases of lipoid pneumonia were “possibly” due to aspiration of lipid-containing over-the-counter agents. The first case was associated with aspiration of mentholated topical ointment applied intranasally, whereas the second case was attributed to probable aspiration of mineral oil for management of chronic constipation. Conclusion Pharmacists in many practice settings can play an integral role in preventing this condition and screening for patients who may warrant a diagnostic workup. During medication reconciliation, pharmacists should identify all prescription and nonprescription medications used by patients. Patients should specifically be asked about lipid-based over-the-counter products and cosmetic agents.

UR - http://www.scopus.com/inward/record.url?scp=85028874526&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85028874526&partnerID=8YFLogxK

U2 - 10.1016/j.japh.2017.05.012

DO - 10.1016/j.japh.2017.05.012

M3 - Article

VL - 57

SP - 616

EP - 618

JO - Journal of the American Pharmacists Association : JAPhA

JF - Journal of the American Pharmacists Association : JAPhA

SN - 1544-3191

IS - 5

ER -