Pharmacodynamic Interactions with Exercise and Beta-Blocker Medications

Research output: Contribution to journalReview article

Abstract

It is recommended that all individuals who have high blood pressure should also participate in a regular exercise program to help control their blood pressure and decrease their risk for cardiovascular disease. Most of these individuals will also be on medications, and many will be on a medication from the class of antihypertensives called beta-blockers. Research has shown that a pharmacodynamic drug-exercise interaction exists when beta-blockers and exercise are taken together. Hemodynamic changes occur with this interaction, causing a decrease in exercising heart rate and cardiac output. Clinically, this results in patients feeling fatigued and that their ability to exercise is more difficult, which can result in poor exercise adherence. Health care professionals should routinely talk with their patients who are taking beta-blocker therapy about what to expect when the 2 treatments are taken together. This article provides background information about this drug-exercise interaction and several points of information that health care professionals can discuss with their patients, including how to monitor their exercise intensity without using the exercise heart rate response method.

Original languageEnglish (US)
Pages (from-to)454-457
Number of pages4
JournalAmerican Journal of Lifestyle Medicine
Volume3
Issue number6
DOIs
StatePublished - 2009

Fingerprint

Exercise
Drug Interactions
Heart Rate
Delivery of Health Care
Aptitude
Cardiac Output
Antihypertensive Agents
Emotions
Cardiovascular Diseases
Hemodynamics
Blood Pressure
Hypertension
Therapeutics
Research

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

Pharmacodynamic Interactions with Exercise and Beta-Blocker Medications. / Lenz, Thomas L.

In: American Journal of Lifestyle Medicine, Vol. 3, No. 6, 2009, p. 454-457.

Research output: Contribution to journalReview article

@article{462eb542b1774943ad6eb9e140b44232,
title = "Pharmacodynamic Interactions with Exercise and Beta-Blocker Medications",
abstract = "It is recommended that all individuals who have high blood pressure should also participate in a regular exercise program to help control their blood pressure and decrease their risk for cardiovascular disease. Most of these individuals will also be on medications, and many will be on a medication from the class of antihypertensives called beta-blockers. Research has shown that a pharmacodynamic drug-exercise interaction exists when beta-blockers and exercise are taken together. Hemodynamic changes occur with this interaction, causing a decrease in exercising heart rate and cardiac output. Clinically, this results in patients feeling fatigued and that their ability to exercise is more difficult, which can result in poor exercise adherence. Health care professionals should routinely talk with their patients who are taking beta-blocker therapy about what to expect when the 2 treatments are taken together. This article provides background information about this drug-exercise interaction and several points of information that health care professionals can discuss with their patients, including how to monitor their exercise intensity without using the exercise heart rate response method.",
author = "Lenz, {Thomas L.}",
year = "2009",
doi = "10.1177/1559827609344523",
language = "English (US)",
volume = "3",
pages = "454--457",
journal = "American Journal of Lifestyle Medicine",
issn = "1559-8276",
publisher = "SAGE Publications Inc.",
number = "6",

}

TY - JOUR

T1 - Pharmacodynamic Interactions with Exercise and Beta-Blocker Medications

AU - Lenz, Thomas L.

PY - 2009

Y1 - 2009

N2 - It is recommended that all individuals who have high blood pressure should also participate in a regular exercise program to help control their blood pressure and decrease their risk for cardiovascular disease. Most of these individuals will also be on medications, and many will be on a medication from the class of antihypertensives called beta-blockers. Research has shown that a pharmacodynamic drug-exercise interaction exists when beta-blockers and exercise are taken together. Hemodynamic changes occur with this interaction, causing a decrease in exercising heart rate and cardiac output. Clinically, this results in patients feeling fatigued and that their ability to exercise is more difficult, which can result in poor exercise adherence. Health care professionals should routinely talk with their patients who are taking beta-blocker therapy about what to expect when the 2 treatments are taken together. This article provides background information about this drug-exercise interaction and several points of information that health care professionals can discuss with their patients, including how to monitor their exercise intensity without using the exercise heart rate response method.

AB - It is recommended that all individuals who have high blood pressure should also participate in a regular exercise program to help control their blood pressure and decrease their risk for cardiovascular disease. Most of these individuals will also be on medications, and many will be on a medication from the class of antihypertensives called beta-blockers. Research has shown that a pharmacodynamic drug-exercise interaction exists when beta-blockers and exercise are taken together. Hemodynamic changes occur with this interaction, causing a decrease in exercising heart rate and cardiac output. Clinically, this results in patients feeling fatigued and that their ability to exercise is more difficult, which can result in poor exercise adherence. Health care professionals should routinely talk with their patients who are taking beta-blocker therapy about what to expect when the 2 treatments are taken together. This article provides background information about this drug-exercise interaction and several points of information that health care professionals can discuss with their patients, including how to monitor their exercise intensity without using the exercise heart rate response method.

UR - http://www.scopus.com/inward/record.url?scp=84990317008&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84990317008&partnerID=8YFLogxK

U2 - 10.1177/1559827609344523

DO - 10.1177/1559827609344523

M3 - Review article

VL - 3

SP - 454

EP - 457

JO - American Journal of Lifestyle Medicine

JF - American Journal of Lifestyle Medicine

SN - 1559-8276

IS - 6

ER -