Abstract
Background: There is much interest in dosing vitamin D intermittently for patient convenience and long-term adherence. Objective: The objective was to characterize the time course and response of 25-hydroxyvitamin D (calcidiol) to a large oral dose of cholecalciferol. Design: One group (30 subjects) was supplemented with a single oral dose of 100 000 IU cholecalciferol. A second group (10 subjects) served as a control group to assess the seasonal change of calcidiol. Serum calcidiol concentrations were followed for 4 mo. The subjects were healthy with limited sun exposure (
| Original language | English |
|---|---|
| Pages (from-to) | 688-691 |
| Number of pages | 4 |
| Journal | American Journal of Clinical Nutrition |
| Volume | 87 |
| Issue number | 3 |
| State | Published - Mar 1 2008 |
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All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- Food Science
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Pharmacokinetics of a single, large dose of cholecalciferol. / Ilahi, Marium; Armas, Laura A G; Heaney, Robert P.
In: American Journal of Clinical Nutrition, Vol. 87, No. 3, 01.03.2008, p. 688-691.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pharmacokinetics of a single, large dose of cholecalciferol
AU - Ilahi, Marium
AU - Armas, Laura A G
AU - Heaney, Robert P.
PY - 2008/3/1
Y1 - 2008/3/1
N2 - Background: There is much interest in dosing vitamin D intermittently for patient convenience and long-term adherence. Objective: The objective was to characterize the time course and response of 25-hydroxyvitamin D (calcidiol) to a large oral dose of cholecalciferol. Design: One group (30 subjects) was supplemented with a single oral dose of 100 000 IU cholecalciferol. A second group (10 subjects) served as a control group to assess the seasonal change of calcidiol. Serum calcidiol concentrations were followed for 4 mo. The subjects were healthy with limited sun exposure (
AB - Background: There is much interest in dosing vitamin D intermittently for patient convenience and long-term adherence. Objective: The objective was to characterize the time course and response of 25-hydroxyvitamin D (calcidiol) to a large oral dose of cholecalciferol. Design: One group (30 subjects) was supplemented with a single oral dose of 100 000 IU cholecalciferol. A second group (10 subjects) served as a control group to assess the seasonal change of calcidiol. Serum calcidiol concentrations were followed for 4 mo. The subjects were healthy with limited sun exposure (
UR - http://www.scopus.com/inward/record.url?scp=40549104752&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40549104752&partnerID=8YFLogxK
M3 - Article
C2 - 18326608
AN - SCOPUS:40549104752
VL - 87
SP - 688
EP - 691
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
SN - 0002-9165
IS - 3
ER -