Abstract
Bone mineral consists of calcium phosphate, and phosphorus is as important as calcium in supporting bone augmentation and maintenance. Although typical adult diets contain abundant phosphorus, 10% to 15% of older women have intakes of less than 70% of the recommended daily allowance. When these women take high-dose calcium supplements that consist of the carbonate or citrate salts, all their food phosphorus may be bound and hence unavailable for absorption. Current-generation anabolic agents for treating osteoporosis require positive phosphorus balances of up to 90 mg/d. Attention to the nutritional adequacy of the diets of such patients is essential if they are to realize the full potential of such therapies. A calcium phosphate supplement may be preferable to the usual carbonate or citrate salts because its phosphate serves to spare food phosphorus.
| Original language | English |
|---|---|
| Pages (from-to) | 91-97 |
| Number of pages | 7 |
| Journal | Mayo Clinic Proceedings |
| Volume | 79 |
| Issue number | 1 |
| State | Published - 2004 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
Phosphorus Nutrition and the Treatment of Osteoporosis. / Heaney, Robert P.
In: Mayo Clinic Proceedings, Vol. 79, No. 1, 2004, p. 91-97.Research output: Contribution to journal › Review article
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TY - JOUR
T1 - Phosphorus Nutrition and the Treatment of Osteoporosis
AU - Heaney, Robert P.
PY - 2004
Y1 - 2004
N2 - Bone mineral consists of calcium phosphate, and phosphorus is as important as calcium in supporting bone augmentation and maintenance. Although typical adult diets contain abundant phosphorus, 10% to 15% of older women have intakes of less than 70% of the recommended daily allowance. When these women take high-dose calcium supplements that consist of the carbonate or citrate salts, all their food phosphorus may be bound and hence unavailable for absorption. Current-generation anabolic agents for treating osteoporosis require positive phosphorus balances of up to 90 mg/d. Attention to the nutritional adequacy of the diets of such patients is essential if they are to realize the full potential of such therapies. A calcium phosphate supplement may be preferable to the usual carbonate or citrate salts because its phosphate serves to spare food phosphorus.
AB - Bone mineral consists of calcium phosphate, and phosphorus is as important as calcium in supporting bone augmentation and maintenance. Although typical adult diets contain abundant phosphorus, 10% to 15% of older women have intakes of less than 70% of the recommended daily allowance. When these women take high-dose calcium supplements that consist of the carbonate or citrate salts, all their food phosphorus may be bound and hence unavailable for absorption. Current-generation anabolic agents for treating osteoporosis require positive phosphorus balances of up to 90 mg/d. Attention to the nutritional adequacy of the diets of such patients is essential if they are to realize the full potential of such therapies. A calcium phosphate supplement may be preferable to the usual carbonate or citrate salts because its phosphate serves to spare food phosphorus.
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M3 - Review article
VL - 79
SP - 91
EP - 97
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
SN - 0025-6196
IS - 1
ER -