Plasma fentanyl levels in infants undergoing extracorporeal membrane oxygenation

M. P. Leuschen, L. D. Willett, E. B. Hoie, D. L. Bolam, M. E. Bussey, P. D. Goodrich, T. L. Zach, R. M. Nelson

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

Plasma levels of fentanyl were analyzed in 12 infants undergoing extracorporeal membrane oxygenation who received a fentanyl bolus (5 to 10 μg/kg) followed by infusion at 1 to 6.3 μg/kg/hr. Fentanyl levels, averaging 11 samples/infant, were measured by radioimmunoassay (mean 19.7 ± 35.7 ng/ml; n = 140). Eight of the infants, all with a primary diagnosis other than congenital diaphragmatic hernia, survived with relatively short (

Original languageEnglish (US)
Pages (from-to)885-891
Number of pages7
JournalJournal of Thoracic and Cardiovascular Surgery
Volume105
Issue number5
DOIs
StatePublished - 1993

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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    Leuschen, M. P., Willett, L. D., Hoie, E. B., Bolam, D. L., Bussey, M. E., Goodrich, P. D., Zach, T. L., & Nelson, R. M. (1993). Plasma fentanyl levels in infants undergoing extracorporeal membrane oxygenation. Journal of Thoracic and Cardiovascular Surgery, 105(5), 885-891. https://doi.org/10.1016/s0022-5223(19)34161-3