Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

Ashfaque Hossain, M. J. Ferraro, R. M. Pino, R. B. Dew, E. S. Moland, T. J. Lockhart, K. S. Thomson, R. V. Goering, N. D. Hanson

Research output: Contribution to journalArticlepeer-review

97 Scopus citations


A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

Original languageEnglish (US)
Pages (from-to)4438-4440
Number of pages3
JournalAntimicrobial agents and chemotherapy
Issue number11
StatePublished - Nov 2004

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


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