Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

Ashfaque Hossain; M. J. Ferraro; R. M. Pino; R. B. Dew; E. S. Moland; T. J. Lockhart; K. S. Thomson; R. V. Goering; N. D. Hanson

doi:10.1128/AAC.48.11.4438-4440.2004

Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

Ashfaque Hossain, M. J. Ferraro, R. M. Pino, R. B. Dew, E. S. Moland, T. J. Lockhart, K. S. Thomson, R. V. Goering, N. D. Hanson

Department of Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

Original language	English (US)
Pages (from-to)	4438-4440
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	48
Issue number	11
DOIs	https://doi.org/10.1128/AAC.48.11.4438-4440.2004
State	Published - Nov 2004

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.48.11.4438-4440.2004

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title = "Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.",

abstract = "A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.",

author = "Ashfaque Hossain and Ferraro, {M. J.} and Pino, {R. M.} and Dew, {R. B.} and Moland, {E. S.} and Lockhart, {T. J.} and Thomson, {K. S.} and Goering, {R. V.} and Hanson, {N. D.}",

year = "2004",

month = nov,

doi = "10.1128/AAC.48.11.4438-4440.2004",

language = "English (US)",

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journal = "Antimicrobial Agents and Chemotherapy",

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AU - Hossain, Ashfaque

AU - Ferraro, M. J.

AU - Pino, R. M.

AU - Dew, R. B.

AU - Moland, E. S.

AU - Lockhart, T. J.

AU - Thomson, K. S.

AU - Goering, R. V.

AU - Hanson, N. D.

PY - 2004/11

Y1 - 2004/11

N2 - A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

AB - A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

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JO - Antimicrobial Agents and Chemotherapy

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SN - 0066-4804

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ER -

Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

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