Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

Ashfaque Hossain, M. J. Ferraro, R. M. Pino, R. B. Dew, E. S. Moland, T. J. Lockhart, K. S. Thomson, Richard V. Goering, Nancy D. Hanson

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

Original languageEnglish
Pages (from-to)4438-4440
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume48
Issue number11
DOIs
StatePublished - Nov 2004

Fingerprint

Enterobacter
Carbapenems
Plasmids
Imipenem
Enzymes
Sepsis

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp. / Hossain, Ashfaque; Ferraro, M. J.; Pino, R. M.; Dew, R. B.; Moland, E. S.; Lockhart, T. J.; Thomson, K. S.; Goering, Richard V.; Hanson, Nancy D.

In: Antimicrobial Agents and Chemotherapy, Vol. 48, No. 11, 11.2004, p. 4438-4440.

Research output: Contribution to journalArticle

Hossain, A, Ferraro, MJ, Pino, RM, Dew, RB, Moland, ES, Lockhart, TJ, Thomson, KS, Goering, RV & Hanson, ND 2004, 'Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.', Antimicrobial Agents and Chemotherapy, vol. 48, no. 11, pp. 4438-4440. https://doi.org/10.1128/AAC.48.11.4438-4440.2004
Hossain, Ashfaque ; Ferraro, M. J. ; Pino, R. M. ; Dew, R. B. ; Moland, E. S. ; Lockhart, T. J. ; Thomson, K. S. ; Goering, Richard V. ; Hanson, Nancy D. / Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp. In: Antimicrobial Agents and Chemotherapy. 2004 ; Vol. 48, No. 11. pp. 4438-4440.
@article{6886bbd8e15f4ccc915737546b155579,
title = "Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.",
abstract = "A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.",
author = "Ashfaque Hossain and Ferraro, {M. J.} and Pino, {R. M.} and Dew, {R. B.} and Moland, {E. S.} and Lockhart, {T. J.} and Thomson, {K. S.} and Goering, {Richard V.} and Hanson, {Nancy D.}",
year = "2004",
month = "11",
doi = "10.1128/AAC.48.11.4438-4440.2004",
language = "English",
volume = "48",
pages = "4438--4440",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "11",

}

TY - JOUR

T1 - Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

AU - Hossain, Ashfaque

AU - Ferraro, M. J.

AU - Pino, R. M.

AU - Dew, R. B.

AU - Moland, E. S.

AU - Lockhart, T. J.

AU - Thomson, K. S.

AU - Goering, Richard V.

AU - Hanson, Nancy D.

PY - 2004/11

Y1 - 2004/11

N2 - A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

AB - A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

UR - http://www.scopus.com/inward/record.url?scp=7244250110&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=7244250110&partnerID=8YFLogxK

U2 - 10.1128/AAC.48.11.4438-4440.2004

DO - 10.1128/AAC.48.11.4438-4440.2004

M3 - Article

C2 - 15504876

AN - SCOPUS:7244250110

VL - 48

SP - 4438

EP - 4440

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 11

ER -