Ploidy variation in fungi

Polyploidy, aneuploidy, and genome evolution

Robert T. Todd, Anja Forche, Anna Selmecki

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The ability of an organism to replicate and segregate its genome with high fidelity is vital to its survival and for the production of future generations. Errors in either of these steps (replication or segregation) can lead to a change in ploidy or chromosome number. While these drastic genome changes can be detrimental to the organism, resulting in decreased fitness, they can also provide increased fitness during periods of stress. A change in ploidy or chromosome number can fundamentally change how a cell senses and responds to its environment. Here, we discuss current ideas in fungal biology that illuminate how eukaryotic genome size variation can impact the organism at a cellular and evolutionary level. One of the most fascinating observations from the past 2 decades of research is that some fungi have evolved the ability to tolerate large genome size changes and generate vast genomic heterogeneity without undergoing canonical meiosis.

Original languageEnglish (US)
Article numberFUNK-0051-2016
JournalMicrobiology spectrum
Volume5
Issue number4
DOIs
StatePublished - Jul 1 2017

Fingerprint

Genome Size
polyploidy
Aptitude
Polyploidy
ploidy
Ploidies
Aneuploidy
Fungi
genome
Chromosomes
fungus
Genome
Social Responsibility
Meiosis
chromosome
fitness
Research
genomics
organism

All Science Journal Classification (ASJC) codes

  • Physiology
  • Ecology
  • Immunology and Microbiology(all)
  • Genetics
  • Cell Biology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Ploidy variation in fungi : Polyploidy, aneuploidy, and genome evolution. / Todd, Robert T.; Forche, Anja; Selmecki, Anna.

In: Microbiology spectrum, Vol. 5, No. 4, FUNK-0051-2016, 01.07.2017.

Research output: Contribution to journalArticle

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