Abstract
A prospective, population-based laboratory surveillance study was conducted to define the epidemiology of extended-spectrum β-lactamase-producing Escherichia coli infections in the Calgary Health Region during the years 2000-2002. The incidence was 5.5 cases per 100,000 population per year. The annualized incidence of 3.9 cases per 100,000 population for January through March was significantly lower than the incidence for the other quarters of the year (6.0 per 100,000 population; PCTX-M genes from the CTX-M-I subgroup and 87 (55%) from the CTX-M-III subgroup. Ciprofloxacin resistance was independently associated with CTX-M-β-lactamases (odds ratio, 14.2; 95% confidence interval, 3.69-54.84). Strains of E. coli with blaCTX-M genes commonly cause community-onset infections, and women and older patients are at highest risk.
| Original language | English |
|---|---|
| Pages (from-to) | 1736-1741 |
| Number of pages | 6 |
| Journal | Clinical Infectious Diseases |
| Volume | 38 |
| Issue number | 12 |
| DOIs | |
| State | Published - Jun 15 2004 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Immunology
Cite this
Population-based laboratory surveillance for Escherichia coli-producing extended-spectrum β-Lactamases : Importance of community isolates with blaCTX-M genes. / Pitout, Johann D D; Hanson, Nancy D.; Church, Deirdre L.; Laupland, Kevin B.
In: Clinical Infectious Diseases, Vol. 38, No. 12, 15.06.2004, p. 1736-1741.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Population-based laboratory surveillance for Escherichia coli-producing extended-spectrum β-Lactamases
T2 - Importance of community isolates with blaCTX-M genes
AU - Pitout, Johann D D
AU - Hanson, Nancy D.
AU - Church, Deirdre L.
AU - Laupland, Kevin B.
PY - 2004/6/15
Y1 - 2004/6/15
N2 - A prospective, population-based laboratory surveillance study was conducted to define the epidemiology of extended-spectrum β-lactamase-producing Escherichia coli infections in the Calgary Health Region during the years 2000-2002. The incidence was 5.5 cases per 100,000 population per year. The annualized incidence of 3.9 cases per 100,000 population for January through March was significantly lower than the incidence for the other quarters of the year (6.0 per 100,000 population; PCTX-M genes from the CTX-M-I subgroup and 87 (55%) from the CTX-M-III subgroup. Ciprofloxacin resistance was independently associated with CTX-M-β-lactamases (odds ratio, 14.2; 95% confidence interval, 3.69-54.84). Strains of E. coli with blaCTX-M genes commonly cause community-onset infections, and women and older patients are at highest risk.
AB - A prospective, population-based laboratory surveillance study was conducted to define the epidemiology of extended-spectrum β-lactamase-producing Escherichia coli infections in the Calgary Health Region during the years 2000-2002. The incidence was 5.5 cases per 100,000 population per year. The annualized incidence of 3.9 cases per 100,000 population for January through March was significantly lower than the incidence for the other quarters of the year (6.0 per 100,000 population; PCTX-M genes from the CTX-M-I subgroup and 87 (55%) from the CTX-M-III subgroup. Ciprofloxacin resistance was independently associated with CTX-M-β-lactamases (odds ratio, 14.2; 95% confidence interval, 3.69-54.84). Strains of E. coli with blaCTX-M genes commonly cause community-onset infections, and women and older patients are at highest risk.
UR - http://www.scopus.com/inward/record.url?scp=2942639503&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2942639503&partnerID=8YFLogxK
U2 - 10.1086/421094
DO - 10.1086/421094
M3 - Article
C2 - 15227620
AN - SCOPUS:2942639503
VL - 38
SP - 1736
EP - 1741
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - 12
ER -