Possible Immune Origin of Pemphigus

J. C. Roujeau, J. Revuz, J. C. Guillaume, R. Touraine, Robert G. Townley, Linda Ford

Research output: Contribution to journalLetter

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Abstract

To the Editor: The paper by Anhalt et al. (May 20 issue)1 demonstrates that the passive transfer of IgG from patients with pemphigus induces the disease in neonatal mice and provides one more piece of evidence for a pathogenic role of pemphigus autoantibody. We agree with Provost2 that “new studies should be designed to determine whether therapy should be aimed primarily at elimination of the pemphigus antibody.” With such a goal in mind we have been using large-volume plasma exchanges for three years in 11 patients with pemphigus. Among these 11 patients plasma exchanges were very useful in controlling.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Volume307
Issue number19
DOIs
StatePublished - Nov 4 1982

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Roujeau, J. C., Revuz, J., Guillaume, J. C., Touraine, R., Townley, R. G., & Ford, L. (1982). Possible Immune Origin of Pemphigus. New England Journal of Medicine, 307(19). https://doi.org/10.1056/NEJM198211043071914