Possible Immune Origin of Pemphigus

J. C. Roujeau; J. Revuz; J. C. Guillaume; R. Touraine; Robert G. Townley; Linda Ford

doi:10.1056/NEJM198211043071914

Possible Immune Origin of Pemphigus

J. C. Roujeau, J. Revuz, J. C. Guillaume, R. Touraine, Robert G. Townley, Linda Ford

Department of Medicine

Research output: Contribution to journal › Letter

7 Scopus citations

Abstract

To the Editor: The paper by Anhalt et al. (May 20 issue)¹ demonstrates that the passive transfer of IgG from patients with pemphigus induces the disease in neonatal mice and provides one more piece of evidence for a pathogenic role of pemphigus autoantibody. We agree with Provost² that “new studies should be designed to determine whether therapy should be aimed primarily at elimination of the pemphigus antibody.” With such a goal in mind we have been using large-volume plasma exchanges for three years in 11 patients with pemphigus. Among these 11 patients plasma exchanges were very useful in controlling.

Original language	English (US)
Number of pages	1
Journal	New England Journal of Medicine
Volume	307
Issue number	19
DOIs	https://doi.org/10.1056/NEJM198211043071914
State	Published - Nov 4 1982

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1056/NEJM198211043071914

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Roujeau, J. C., Revuz, J., Guillaume, J. C., Touraine, R., Townley, R. G., & Ford, L. (1982). Possible Immune Origin of Pemphigus. New England Journal of Medicine, 307(19). https://doi.org/10.1056/NEJM198211043071914

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T1 - Possible Immune Origin of Pemphigus

AU - Roujeau, J. C.

AU - Revuz, J.

AU - Guillaume, J. C.

AU - Touraine, R.

AU - Townley, Robert G.

AU - Ford, Linda

PY - 1982/11/4

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N2 - To the Editor: The paper by Anhalt et al. (May 20 issue)1 demonstrates that the passive transfer of IgG from patients with pemphigus induces the disease in neonatal mice and provides one more piece of evidence for a pathogenic role of pemphigus autoantibody. We agree with Provost2 that “new studies should be designed to determine whether therapy should be aimed primarily at elimination of the pemphigus antibody.” With such a goal in mind we have been using large-volume plasma exchanges for three years in 11 patients with pemphigus. Among these 11 patients plasma exchanges were very useful in controlling.

AB - To the Editor: The paper by Anhalt et al. (May 20 issue)1 demonstrates that the passive transfer of IgG from patients with pemphigus induces the disease in neonatal mice and provides one more piece of evidence for a pathogenic role of pemphigus autoantibody. We agree with Provost2 that “new studies should be designed to determine whether therapy should be aimed primarily at elimination of the pemphigus antibody.” With such a goal in mind we have been using large-volume plasma exchanges for three years in 11 patients with pemphigus. Among these 11 patients plasma exchanges were very useful in controlling.

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