Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p

Original languageEnglish
Pages (from-to)1055-1060
Number of pages6
JournalPharmacotherapy
Volume21
Issue number9 I
StatePublished - 2001

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Acute Coronary Syndrome
LDL Cholesterol
LDL Lipoproteins
Chest Pain
Inpatients
Outpatients
Cholesterol
Hypolipidemic Agents
Education
Tertiary Healthcare
Therapeutics
Tertiary Care Centers
Observational Studies
Coronary Disease
Prospective Studies
Lipids

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

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title = "Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome",
abstract = "Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p",
author = "Faulkner, {Michele A.} and Hilleman, {Daniel E.} and Destache, {Christopher J.} and Mooss, {Aryan N.}",
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T1 - Potential influence of timing of low-density lipoprotein cholesterol evaluation in patients with acute coronary syndrome

AU - Faulkner, Michele A.

AU - Hilleman, Daniel E.

AU - Destache, Christopher J.

AU - Mooss, Aryan N.

PY - 2001

Y1 - 2001

N2 - Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p

AB - Objective. To determine the significance of timing of low-density lipoprotein (LDL) cholesterol evaluation in patients with chest pain as it relates to subsequent National Cholesterol Education Program (NCEP) treatment decisions. Design. Prospective, observational study. Setting. A university-affiliated tertiary care hospital. Patients. Sixty-two patients with coronary heart disease who were not receiving lipid-lowering therapy and whose LDL levels were obtained 25-48 hours after onset of chest pain. Intervention. We evaluated laboratory test results of patients with chest pain admitted to the cardiac care unit to determine risk to patients when LDL levels obtained inappropriately are used to make decisions regarding antihyperlipidemic therapy. Measurements and Main Results. Inpatient and outpatient LDL levels were compared, and changes in NCEP treatment decisions analyzed. Differences between inpatient and outpatient LDL levels were significant (p

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