Predictors of outcome in 101 patients requiring emergent thoracotomy for penetrating pulmonary injuries

Juan A. Asensio, O. A. Ogun, F. N. Mazzini, A. J. Perez-Alonso, L. M. Garcia-Núñez, P. Petrone

Research output: Contribution to journalArticle

Abstract

Background: Operative interventions are uncommonly required for penetrating pulmonary injuries. Similarly, because their incidence is low, few series appear sporadically in the literature. Objectives of this study are to identify predictors of outcome for patients requiring emergent thoracotomy for penetrating pulmonary injuries and evaluate the use of tissue sparing versus resective techniques for their management. Study design: This is a retrospective 169-month study of all patients with penetrating pulmonary injuries requiring thoracotomy. The main outcome measures are: physiologic parameters, AAST-OIS injury grade, surgical procedures and mortality. Statistical analysis includes univariate and stepwise logistic regression. Results: 101 patients required thoracotomy for penetrating pulmonary injuries. Mechanism of injury includes: gunshot wounds (GSW)—73 (72%), stab wounds (SW)—28 (33%). Mean systolic BP 97 ± 47, mean HR 92 ± 47, and mean admission pH 7.22 ± 0.17. Mean RTS 6.25 ± 2.7, mean ISS 36 ± 22. The mean estimated blood loss (EBL) was 5277 ± 4955 mls. Predictors of outcome are: admission pH (p = 0.0014), admission base deficit (p < 0.0001), packed red blood cells (PRBCs) transfused (p = 0.023), whole blood transfused (p < 0.01). A total of 143 procedures were required in 101 patients: tissue sparing 114 (80%) versus resective procedures 29 (20%). Only pneumonectomy (p = 0.024) predicted outcome. Overall survival 64/101–64%. American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) injury grades I–III versus IV–VI predicts survival (p < 0.001). Stepwise logistic regression identified AAST-OIS injury grades IV–VI (p = 0.007; OR 6.38 [95% CI 1.64–24.78]), intraoperative dysrhythmias (p = 0.003; OR 17.38 [95% CI 2.59–116.49]) and associated cardiac injuries (p = 0.02; OR 8.74 [95% CI 1.37–55.79]) as independent predictors of outcome. Conclusions: Predictors of outcome for penetrating pulmonary injuries requiring thoracotomy are identified and must be taken into account in their operative management. Tissue sparing techniques—stapled pulmonary tractotomy is once again validated, and it remains effective as the mainstay for their management; however, only pneumonectomy predicts outcome. AAST-OIS injury grades IV–VI predict outcome with higher injury grades requiring resective procedures.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalEuropean Journal of Trauma and Emergency Surgery
DOIs
StateAccepted/In press - Jun 1 2017

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Lung Injury
Thoracotomy
Wounds and Injuries
Pneumonectomy
Logistic Models
Stab Wounds
Gunshot Wounds
Survival
Intraoperative Complications
Erythrocytes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Emergency Medicine
  • Orthopedics and Sports Medicine
  • Critical Care and Intensive Care Medicine

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Predictors of outcome in 101 patients requiring emergent thoracotomy for penetrating pulmonary injuries. / Asensio, Juan A.; Ogun, O. A.; Mazzini, F. N.; Perez-Alonso, A. J.; Garcia-Núñez, L. M.; Petrone, P.

In: European Journal of Trauma and Emergency Surgery, 01.06.2017, p. 1-7.

Research output: Contribution to journalArticle

Asensio, Juan A. ; Ogun, O. A. ; Mazzini, F. N. ; Perez-Alonso, A. J. ; Garcia-Núñez, L. M. ; Petrone, P. / Predictors of outcome in 101 patients requiring emergent thoracotomy for penetrating pulmonary injuries. In: European Journal of Trauma and Emergency Surgery. 2017 ; pp. 1-7.
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abstract = "Background: Operative interventions are uncommonly required for penetrating pulmonary injuries. Similarly, because their incidence is low, few series appear sporadically in the literature. Objectives of this study are to identify predictors of outcome for patients requiring emergent thoracotomy for penetrating pulmonary injuries and evaluate the use of tissue sparing versus resective techniques for their management. Study design: This is a retrospective 169-month study of all patients with penetrating pulmonary injuries requiring thoracotomy. The main outcome measures are: physiologic parameters, AAST-OIS injury grade, surgical procedures and mortality. Statistical analysis includes univariate and stepwise logistic regression. Results: 101 patients required thoracotomy for penetrating pulmonary injuries. Mechanism of injury includes: gunshot wounds (GSW)—73 (72{\%}), stab wounds (SW)—28 (33{\%}). Mean systolic BP 97 ± 47, mean HR 92 ± 47, and mean admission pH 7.22 ± 0.17. Mean RTS 6.25 ± 2.7, mean ISS 36 ± 22. The mean estimated blood loss (EBL) was 5277 ± 4955 mls. Predictors of outcome are: admission pH (p = 0.0014), admission base deficit (p < 0.0001), packed red blood cells (PRBCs) transfused (p = 0.023), whole blood transfused (p < 0.01). A total of 143 procedures were required in 101 patients: tissue sparing 114 (80{\%}) versus resective procedures 29 (20{\%}). Only pneumonectomy (p = 0.024) predicted outcome. Overall survival 64/101–64{\%}. American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) injury grades I–III versus IV–VI predicts survival (p < 0.001). Stepwise logistic regression identified AAST-OIS injury grades IV–VI (p = 0.007; OR 6.38 [95{\%} CI 1.64–24.78]), intraoperative dysrhythmias (p = 0.003; OR 17.38 [95{\%} CI 2.59–116.49]) and associated cardiac injuries (p = 0.02; OR 8.74 [95{\%} CI 1.37–55.79]) as independent predictors of outcome. Conclusions: Predictors of outcome for penetrating pulmonary injuries requiring thoracotomy are identified and must be taken into account in their operative management. Tissue sparing techniques—stapled pulmonary tractotomy is once again validated, and it remains effective as the mainstay for their management; however, only pneumonectomy predicts outcome. AAST-OIS injury grades IV–VI predict outcome with higher injury grades requiring resective procedures.",
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AU - Mazzini, F. N.

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AU - Garcia-Núñez, L. M.

AU - Petrone, P.

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N2 - Background: Operative interventions are uncommonly required for penetrating pulmonary injuries. Similarly, because their incidence is low, few series appear sporadically in the literature. Objectives of this study are to identify predictors of outcome for patients requiring emergent thoracotomy for penetrating pulmonary injuries and evaluate the use of tissue sparing versus resective techniques for their management. Study design: This is a retrospective 169-month study of all patients with penetrating pulmonary injuries requiring thoracotomy. The main outcome measures are: physiologic parameters, AAST-OIS injury grade, surgical procedures and mortality. Statistical analysis includes univariate and stepwise logistic regression. Results: 101 patients required thoracotomy for penetrating pulmonary injuries. Mechanism of injury includes: gunshot wounds (GSW)—73 (72%), stab wounds (SW)—28 (33%). Mean systolic BP 97 ± 47, mean HR 92 ± 47, and mean admission pH 7.22 ± 0.17. Mean RTS 6.25 ± 2.7, mean ISS 36 ± 22. The mean estimated blood loss (EBL) was 5277 ± 4955 mls. Predictors of outcome are: admission pH (p = 0.0014), admission base deficit (p < 0.0001), packed red blood cells (PRBCs) transfused (p = 0.023), whole blood transfused (p < 0.01). A total of 143 procedures were required in 101 patients: tissue sparing 114 (80%) versus resective procedures 29 (20%). Only pneumonectomy (p = 0.024) predicted outcome. Overall survival 64/101–64%. American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) injury grades I–III versus IV–VI predicts survival (p < 0.001). Stepwise logistic regression identified AAST-OIS injury grades IV–VI (p = 0.007; OR 6.38 [95% CI 1.64–24.78]), intraoperative dysrhythmias (p = 0.003; OR 17.38 [95% CI 2.59–116.49]) and associated cardiac injuries (p = 0.02; OR 8.74 [95% CI 1.37–55.79]) as independent predictors of outcome. Conclusions: Predictors of outcome for penetrating pulmonary injuries requiring thoracotomy are identified and must be taken into account in their operative management. Tissue sparing techniques—stapled pulmonary tractotomy is once again validated, and it remains effective as the mainstay for their management; however, only pneumonectomy predicts outcome. AAST-OIS injury grades IV–VI predict outcome with higher injury grades requiring resective procedures.

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