Abstract
Infection with HIV, which is the cause of AIDS, is a major public-health concern throughout the world, especially in developing countries. Once a person is infected with HIV, he or she remains infected for life, even with treatment. Despite the success of standard regimens, antiretroviral therapy is complicated by potential drug-drug interactions, patient nonadherence, and adverse effects. Therefore, developing a safe, effective vaccine that prevents HIV infection is the best strategy for containing the epidemic. Despite progress in vaccine development, there is still no effective vaccine for preventing HIV. Because HIV is highly diverse, it integrates into the host genome and develops ways to evade the immune system. Many roadblocks persist in the field of HIV vaccine development.
| Original language | English |
|---|---|
| Pages | 46-50 |
| Number of pages | 5 |
| Volume | 40 |
| No | 10 |
| Specialist publication | U.S. Pharmacist |
| State | Published - Oct 16 2015 |
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All Science Journal Classification (ASJC) codes
- Pharmaceutical Science
- Pharmacology
- Pharmacy
Cite this
Preventive HIV vaccines : Progress and challenges. / Bossou, Ayoko R.; Castillo, Shana; O’Brien, Karen K.; Opere, Catherine A.; Destache, Christopher J.
In: U.S. Pharmacist, Vol. 40, No. 10, 16.10.2015, p. 46-50.Research output: Contribution to specialist publication › Article
}
TY - GEN
T1 - Preventive HIV vaccines
T2 - Progress and challenges
AU - Bossou, Ayoko R.
AU - Castillo, Shana
AU - O’Brien, Karen K.
AU - Opere, Catherine A.
AU - Destache, Christopher J.
PY - 2015/10/16
Y1 - 2015/10/16
N2 - Infection with HIV, which is the cause of AIDS, is a major public-health concern throughout the world, especially in developing countries. Once a person is infected with HIV, he or she remains infected for life, even with treatment. Despite the success of standard regimens, antiretroviral therapy is complicated by potential drug-drug interactions, patient nonadherence, and adverse effects. Therefore, developing a safe, effective vaccine that prevents HIV infection is the best strategy for containing the epidemic. Despite progress in vaccine development, there is still no effective vaccine for preventing HIV. Because HIV is highly diverse, it integrates into the host genome and develops ways to evade the immune system. Many roadblocks persist in the field of HIV vaccine development.
AB - Infection with HIV, which is the cause of AIDS, is a major public-health concern throughout the world, especially in developing countries. Once a person is infected with HIV, he or she remains infected for life, even with treatment. Despite the success of standard regimens, antiretroviral therapy is complicated by potential drug-drug interactions, patient nonadherence, and adverse effects. Therefore, developing a safe, effective vaccine that prevents HIV infection is the best strategy for containing the epidemic. Despite progress in vaccine development, there is still no effective vaccine for preventing HIV. Because HIV is highly diverse, it integrates into the host genome and develops ways to evade the immune system. Many roadblocks persist in the field of HIV vaccine development.
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M3 - Article
AN - SCOPUS:84944474836
VL - 40
SP - 46
EP - 50
JO - U.S. Pharmacist
JF - U.S. Pharmacist
SN - 0148-4818
ER -