TY - JOUR
T1 - Primary Langerhans cell histiocytosis of the vulva
T2 - Report of a case and brief review of the literature
AU - Pan, Zenggang
AU - Sharma, Sanjeev
AU - Sharma, Poonam
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Primary Langerhans cell histiocytosis (LCH) of the vulva is rare. Fifteen cases of primary cutaneous vulvar LCH have been reported in English literature. We report an additional case of LCH confined to the vulva. In this article, we describe the clinical presentation, histopathology and immunohistochemistry findings of vulvar LCH that are helpful to both gynecologists and pathologists in the diagnosis of this entity. We briefly discuss the pathogenesis of LCH. The debate whether LCH is a reactive or neoplastic entity is still ongoing.
AB - Primary Langerhans cell histiocytosis (LCH) of the vulva is rare. Fifteen cases of primary cutaneous vulvar LCH have been reported in English literature. We report an additional case of LCH confined to the vulva. In this article, we describe the clinical presentation, histopathology and immunohistochemistry findings of vulvar LCH that are helpful to both gynecologists and pathologists in the diagnosis of this entity. We briefly discuss the pathogenesis of LCH. The debate whether LCH is a reactive or neoplastic entity is still ongoing.
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U2 - 10.4103/0377-4929.44968
DO - 10.4103/0377-4929.44968
M3 - Article
C2 - 19136785
AN - SCOPUS:58849097134
VL - 52
SP - 65
EP - 68
JO - Indian Journal of Pathology and Microbiology
JF - Indian Journal of Pathology and Microbiology
SN - 0377-4929
IS - 1
ER -