Abstract
Histiocytoses are a heterogeneous group of disorders which are difficult to categorize because of overlapping clinical and microscopic features, and incompletely understood mechanisms of cellular origin and triggers of proliferation. Progressive nodular histiocytosis (PNH) is a rare non-Langerhans cell histiocytic (NLH) disorder. We present the case of a 34-year-old woman with PNH, who has involvement of the back, head and neck, face, and uniquely, extensive involvement of the posterior pharynx and larynx, which has shown progressive worsening and deformity over a 7-year course. Clinically it is best classified as PNH, although it microscopically closely resembles juvenile and adult xanthogranulomatosis. This study reinforces the concept that the NLH is a closely related group of disorders, possibly representing a spectrum of a single underlying process. Glavin FL, Chhatwall H, Karimi K. Progressive nodular histiocytosis: a case report with literature review, and discussion of differential diagnosis and classification.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1286-1292 |
| Number of pages | 7 |
| Journal | Journal of Cutaneous Pathology |
| Volume | 36 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2009 |
| Externally published | Yes |
Fingerprint
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Histology
- Dermatology
Cite this
Progressive nodular histiocytosis : A case report with literature review, and discussion of differential diagnosis and classification. / Glavin, F. L.; Chehal, Hardeep K.; Karimi, K.
In: Journal of Cutaneous Pathology, Vol. 36, No. 12, 01.12.2009, p. 1286-1292.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Progressive nodular histiocytosis
T2 - A case report with literature review, and discussion of differential diagnosis and classification
AU - Glavin, F. L.
AU - Chehal, Hardeep K.
AU - Karimi, K.
PY - 2009/12/1
Y1 - 2009/12/1
N2 - Histiocytoses are a heterogeneous group of disorders which are difficult to categorize because of overlapping clinical and microscopic features, and incompletely understood mechanisms of cellular origin and triggers of proliferation. Progressive nodular histiocytosis (PNH) is a rare non-Langerhans cell histiocytic (NLH) disorder. We present the case of a 34-year-old woman with PNH, who has involvement of the back, head and neck, face, and uniquely, extensive involvement of the posterior pharynx and larynx, which has shown progressive worsening and deformity over a 7-year course. Clinically it is best classified as PNH, although it microscopically closely resembles juvenile and adult xanthogranulomatosis. This study reinforces the concept that the NLH is a closely related group of disorders, possibly representing a spectrum of a single underlying process. Glavin FL, Chhatwall H, Karimi K. Progressive nodular histiocytosis: a case report with literature review, and discussion of differential diagnosis and classification.
AB - Histiocytoses are a heterogeneous group of disorders which are difficult to categorize because of overlapping clinical and microscopic features, and incompletely understood mechanisms of cellular origin and triggers of proliferation. Progressive nodular histiocytosis (PNH) is a rare non-Langerhans cell histiocytic (NLH) disorder. We present the case of a 34-year-old woman with PNH, who has involvement of the back, head and neck, face, and uniquely, extensive involvement of the posterior pharynx and larynx, which has shown progressive worsening and deformity over a 7-year course. Clinically it is best classified as PNH, although it microscopically closely resembles juvenile and adult xanthogranulomatosis. This study reinforces the concept that the NLH is a closely related group of disorders, possibly representing a spectrum of a single underlying process. Glavin FL, Chhatwall H, Karimi K. Progressive nodular histiocytosis: a case report with literature review, and discussion of differential diagnosis and classification.
UR - http://www.scopus.com/inward/record.url?scp=70350475541&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70350475541&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0560.2009.01454.x
DO - 10.1111/j.1600-0560.2009.01454.x
M3 - Article
VL - 36
SP - 1286
EP - 1292
JO - Journal of Cutaneous Pathology
JF - Journal of Cutaneous Pathology
SN - 0303-6987
IS - 12
ER -