Prolonged survival as a component of hereditary breast and nonpolyposis colon cancer

Henry T. Lynch; William Albano; James Recerbaren; Patrick M. Lynch; Jane F. Lynch; Robert Elston

doi:10.1016/0306-9877(81)90063-3

Prolonged survival as a component of hereditary breast and nonpolyposis colon cancer

Henry T. Lynch, William Albano, James Recerbaren, Patrick M. Lynch, Jane F. Lynch, Robert Elston

Department of Preventive Medicine

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Identification of prolonged survival in hereditary breast and colon cancer (exclusive of familial multiple adenomatous polyposis coli) have been shown to be statistically significant (P <.05) when compared to the American College of Surgeons Tumor Registry for these respective neoplasms. Our hypothesis is that the genotype in hereditary cancer determines both susceptibility and natural history, such that increased survival is a manifestation of the natural history.

Original language	English (US)
Pages (from-to)	1201-1209
Number of pages	9
Journal	Medical Hypotheses
Volume	7
Issue number	9
DOIs	https://doi.org/10.1016/0306-9877(81)90063-3
State	Published - Sep 1981

All Science Journal Classification (ASJC) codes

Medicine(all)

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title = "Prolonged survival as a component of hereditary breast and nonpolyposis colon cancer",

abstract = "Identification of prolonged survival in hereditary breast and colon cancer (exclusive of familial multiple adenomatous polyposis coli) have been shown to be statistically significant (P <.05) when compared to the American College of Surgeons Tumor Registry for these respective neoplasms. Our hypothesis is that the genotype in hereditary cancer determines both susceptibility and natural history, such that increased survival is a manifestation of the natural history.",

author = "Lynch, {Henry T.} and William Albano and James Recerbaren and Lynch, {Patrick M.} and Lynch, {Jane F.} and Robert Elston",

note = "Funding Information: * We gratefully acknowledge support from NCI, Grant No. CA 27831-01 and NCI, Grant No. CA 28198.",

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T1 - Prolonged survival as a component of hereditary breast and nonpolyposis colon cancer

AU - Lynch, Henry T.

AU - Albano, William

AU - Recerbaren, James

AU - Lynch, Patrick M.

AU - Lynch, Jane F.

AU - Elston, Robert

N1 - Funding Information: * We gratefully acknowledge support from NCI, Grant No. CA 27831-01 and NCI, Grant No. CA 28198.

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AB - Identification of prolonged survival in hereditary breast and colon cancer (exclusive of familial multiple adenomatous polyposis coli) have been shown to be statistically significant (P <.05) when compared to the American College of Surgeons Tumor Registry for these respective neoplasms. Our hypothesis is that the genotype in hereditary cancer determines both susceptibility and natural history, such that increased survival is a manifestation of the natural history.

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