Prospective assessment of the use of enamel matrix proteins with minimally invasive surgery

Stephen K. Harrel, Thomas G. Wilson, Martha E. Nunn

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Background: Minimally invasive surgery (MIS) is a surgical technique using very small incisions, indicated for performing regenerative therapy in periodontal defects. Enamel matrix proteins (EMP) have been shown to enhance periodontal regeneration. This study was undertaken to determine the effect of using EMP in combination with an MIS approach. Methods: Patients from two private periodontal practices with chronic periodontitis who, following non-surgical therapy, had one or more sites with probing depths (PD) of ≥6 mm were included in the study. An MIS approach was utilized for surgical access. Following surgical debridement, EMP was placed into the bony defect. The surgical sites were reevaluated after at least 11 months. Results: Surgical treatment was performed at 160 sites in 16 patients. No significant differences were noted in the results between the two offices and the data were combined. Mean PD reduction (P = 0.002) and attachment level improvements (P = 0.012) were significantly greater than 3 mm with mean post-surgical PD of 3.17 mm and attachment levels of 4.05 mm, based on subject means. Mean change in recession following surgery was negligible (0.01 mm). All sites were considered to be clinically successful. Conclusion: The combination of MIS and EMP yields significant reductions in probing depths and improvements in attachment levels while producing little or no increase in recession.

Original languageEnglish
Pages (from-to)380-384
Number of pages5
JournalJournal of Periodontology
Volume76
Issue number3
DOIs
StatePublished - Mar 2005
Externally publishedYes

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Minimally Invasive Surgical Procedures
Chronic Periodontitis
Private Practice
Debridement
Regeneration
Therapeutics
enamel matrix proteins

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

Prospective assessment of the use of enamel matrix proteins with minimally invasive surgery. / Harrel, Stephen K.; Wilson, Thomas G.; Nunn, Martha E.

In: Journal of Periodontology, Vol. 76, No. 3, 03.2005, p. 380-384.

Research output: Contribution to journalArticle

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