Prostate carcinoma and multiple primary malignancies

Study of a family and 109 consecutive prostate cancer patients

Henry T. Lynch, Arthur L. Larsen, Charles W. Magnuson, Anne J. Krush

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A family has been studied wherein 5 of 7 members of a sibship showed carcinoma (all histologically confirmed). Three of the brothers showed carcinoma of the prostate, with 2 of these having an additional separate primary malignancy—one with transitional cell carcinoma of the bladder and the other with bronchogenic carcinoma of the lung. These data were compared with 109 consecutive patients with histologically confirmed prostate carcinoma treated during a 10‐year‐period (1955‐1964). Twenty‐two of the 109 (20%) showed multiple primary malignancies, with 2 showing 5 separate primary malignant neoplasms. Attention is called to the high incidence of multiple malignant neoplasms occurring in association with prostate carcinoma in particular in this series of patients and possibly in patients of comparable age. Possible hereditary factors for this lesion are discussed.

Original languageEnglish
Pages (from-to)1891-1897
Number of pages7
JournalCancer
Volume19
Issue number12
DOIs
StatePublished - 1966
Externally publishedYes

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Prostate
Prostatic Neoplasms
Carcinoma
Neoplasms
Bronchogenic Carcinoma
Transitional Cell Carcinoma
Siblings
Urinary Bladder
Lung
Incidence

All Science Journal Classification (ASJC) codes

  • Cancer Research
  • Oncology

Cite this

Prostate carcinoma and multiple primary malignancies : Study of a family and 109 consecutive prostate cancer patients. / Lynch, Henry T.; Larsen, Arthur L.; Magnuson, Charles W.; Krush, Anne J.

In: Cancer, Vol. 19, No. 12, 1966, p. 1891-1897.

Research output: Contribution to journalArticle

Lynch, Henry T. ; Larsen, Arthur L. ; Magnuson, Charles W. ; Krush, Anne J. / Prostate carcinoma and multiple primary malignancies : Study of a family and 109 consecutive prostate cancer patients. In: Cancer. 1966 ; Vol. 19, No. 12. pp. 1891-1897.
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