Protein-pacing caloric-restriction enhances body composition similarly in obese men and women during weight loss and sustains efficacy during long-term weight maintenance

Paul J. Arciero, Rohan Edmonds, Feng He, Emery Ward, Eric Gumpricht, Alex Mohr, Michael J. Ormsbee, Arne Astrup

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Short-Term protein-pacing (P; ~6 meals/day, >30% protein/day) and caloric restriction (CR, ~25% energy deficit) improves total (TBF), abdominal (ABF) and visceral (VAT) fat loss, energy expenditure, and biomarkers compared to heart healthy (HH) recommendations (3 meals/day, 15% protein/day) in obese adults. Less is known whether obese men and women respond similarly to P-CR during weight loss (WL) and whether a modified P-CR (mP-CR) is more efficacious than a HH diet during long-term (52 week) weight maintenance (WM). The purposes of this study were to evaluate the efficacy of: (1) P-CR on TBF, ABF, resting metabolic rate (RMR), and biomarkers between obese men and women during WL (weeks 0-12); and (2) mP-CR compared to a HH diet during WM (weeks 13-64). During WL, men (n = 21) and women (n = 19) were assessed for TBF, ABF, VAT, RMR, and biomarkers at weeks 0 (pre) and 12 (post). Men and women had similar reductions (p < 0.01) in weight (10%), TBF (19%), ABF (25%), VAT (33%), glucose (7%-12%), insulin (40%), leptin (>50%) and increase in % lean body mass (9%). RMR (kcals/kg bodyweight) was unchanged and respiratory quotient decreased 9%. Twenty-four subjects (mP-CR, n = 10; HH, n = 14) completed WM. mP-CR regained significantly less body weight (6%), TBF (12%), and ABF (17%) compared to HH (p < 0.05). Our results demonstrate P-CR enhances weight loss, body composition and biomarkers, and maintains these changes for 52-weeks compared to a traditional HH diet.

Original languageEnglish (US)
Article number476
JournalNutrients
Volume8
Issue number8
DOIs
StatePublished - Aug 1 2016
Externally publishedYes

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Caloric Restriction
weight control
Body Composition
body composition
Weight Loss
weight loss
heart
Maintenance
Weights and Measures
Basal Metabolism
resting metabolic rate
healthy diet
biomarkers
Biomarkers
Proteins
proteins
Meals
visceral fat
respiratory quotient
body weight

All Science Journal Classification (ASJC) codes

  • Food Science
  • Nutrition and Dietetics

Cite this

Protein-pacing caloric-restriction enhances body composition similarly in obese men and women during weight loss and sustains efficacy during long-term weight maintenance. / Arciero, Paul J.; Edmonds, Rohan; He, Feng; Ward, Emery; Gumpricht, Eric; Mohr, Alex; Ormsbee, Michael J.; Astrup, Arne.

In: Nutrients, Vol. 8, No. 8, 476, 01.08.2016.

Research output: Contribution to journalArticle

Arciero, Paul J. ; Edmonds, Rohan ; He, Feng ; Ward, Emery ; Gumpricht, Eric ; Mohr, Alex ; Ormsbee, Michael J. ; Astrup, Arne. / Protein-pacing caloric-restriction enhances body composition similarly in obese men and women during weight loss and sustains efficacy during long-term weight maintenance. In: Nutrients. 2016 ; Vol. 8, No. 8.
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