Pulmonary mantle cell lymphoma: A rare manifestation of an uncommon condition

Zachary Depew, Robert Vassallo

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Herein we describe the case of a 64-year old man with a history of mantle cell lymphoma found to have evidence of pulmonary parenchymal involvement by recurrence of his lymphoma. While lung involvement is not necessarily uncommon with Non-Hodgkin's lymphomas as a group, it is very rare for mantle cell lymphoma to involve the lung parenchyma. In addition, the radiographic manifestation of his pulmonary lymphoma as a discrete FDGavid ground-glass lesion on chest imaging was also distinctly uncommon for pulmonary lymphoma which classically appears in one of three patterns: scattered ill-defined nodules, a bronchovascular/lymphangitic process, or pneumonic/alveolar consolidation effectively indistinguishable from bacterial pneumonia. Due to significant underlying lung disease our patient was not a candidate for high-dose conditioning and autologous stem cell transplantation. He was ultimately treated with rituximab and cladribine therapy and had early signs of clinical response at last correspondence.

Original languageEnglish
Pages (from-to)30-31
Number of pages2
JournalRare Tumors
Volume4
Issue number1
DOIs
StatePublished - 2012
Externally publishedYes

Fingerprint

Mantle-Cell Lymphoma
Lung
Lymphoma
Cladribine
Bacterial Pneumonia
Stem Cell Transplantation
Non-Hodgkin's Lymphoma
Lung Diseases
Glass
Thorax
Recurrence

All Science Journal Classification (ASJC) codes

  • Oncology
  • Histology

Cite this

Pulmonary mantle cell lymphoma : A rare manifestation of an uncommon condition. / Depew, Zachary; Vassallo, Robert.

In: Rare Tumors, Vol. 4, No. 1, 2012, p. 30-31.

Research output: Contribution to journalArticle

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