Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo

Rhonda Bentley-Lewis, David Aguilar, Matthew C. Riddle, Brian Claggett, Rafael Diaz, Kenneth Dickstein, Hertzel C. Gerstein, Peter Johnston, Lars V. Køber, Francesca Lawson, Eldrin F. Lewis, Aldo P. Maggioni, John J V McMurray, Lin Ping, Jeffrey L. Probstfield, Scott D. Solomon, Jean Claude Tardif, Yujun Wu, Marc A. Pfeffer, Ebrahim Barkoudah & 807 others Abdel Brahimi, David Charytan, Peter Finn, Aiden Flynn, L. Howard Hartley, Galen Henderson, Jacob Joseph, Kayode Odutayo, Vinutha Rajesh, Ali Vazir, Larry Weinrauch, Stefano Del Prato, John Petrie, Allen Kaplan, Phil Lieberman, Bruce L. Zuraw, Eileen O'Reilly, Keyur Patel, Peter Allen, Aldo Scarpa, Mark Schattner, Christopher Granger, Jean Rouleau, David DeMets, Nishi Chaturvedi, Denis Raccah, Diego Aizenberg, Carlos Alvarez, Andres Alvarisqueta, Claudia Baccaro, Ines Bartolacci, Anselmo Bordonava, Miguel Bustamante Labarta, Alberto Caccavo, Pedro Calella, Maria Cantero, Renzo Codutti, Victor Commendatore, Osvaldo Costamagna, Jose Cuello, Alberto Fernandez, Ruben Garcia Duran, Oscar Gomez Vilamajo, Silvia Gorban De Lapertosa, Diego Grinfeld, Sonia Hermida, Mariana Lagrutta, Ricardo Leon De La Fuente, Alberto Licheri, Hector Luciardi, Ignacio Mackinnon, Laura Maffei, Javier Marino, Oscar Montaña, Leonardo Novaretto, Silvia Orio, Andres Orlandini, Alejandra Oviedo, Federico Pérez Manghi, Cristian Patocchi, Hugo Ramos, Florencia Rolandi, Raquel Saa Zarandon, Silvia Salome Saavedra, Lilia Schiavi, Pablo Schygiel, Marcelo Trivi, Maria Ulla, Pedro Urdiales, Julio Vallejos, Marisa Vico, Florencia Waisman, John Amerena, Vincent Paul, Kunwarjit Sangla, William Van Gaal, Bu Yeap, Peter Fasching, Thomas Pieber, Larisa Danilova, Natalya Mitkovskaya, Svetlana Sudzhaeva, Chantal Mathieu, Anne Catherine Pouleur, Roberto Vieira Botelho, Maria Jose Cerqueira, Antonio Chacra, Fabio Dos Santos, Gilson Feitosa, Adriana Forti, Milton Golbert, Alfredo Halpern, Miguel Hissa, Hugo Lisboa, Joao Moraes, Max Nery, Alexandre Quadros, Roberto Raduan, Gilmar Reis, Fernando Ribeiro Filho, Guilherme Rollin, Paulo Rossi, Elizabete Santos, Jose Sgarbi, Juliana Souza, Maria Regina Souza, Alexy Delchev, Valentin Ivanov, Neli Klyuchkova, Michael Kyoleyan, Georgi Levterov, Mariya Lucheva, Dimitar Raev, Rositsa Shumkova, Mariya Tokmakova, Maria Tzekova, Viktor Yordanov, Gordon Bailey, Olivier Bertrand, Rakesh Bhargava, Jeffrey Burton, Jean Campeau, Richard Dumas, Pierre Filteau, Gurcharan Syan, Rajinder Syan, George Tsoukas, James Wayne Warnica, Silvia Acuña, Guillermo Araneda, Lia Bunster, Leonardo Cobos, Ramón Corbalán, Gaston Dussaillant, German Eggers, Fernando Florenzano, Gonzalo Godoy, Laura Andrea Huidobro, Rodolfo Lahsen, Fernando Lanas, Gladys Larenas, Leopoldo Manriquez, Marcelo Medina, Juan Carlos Palma, Luis Perez, Sergio Potthoff, Carlos Raffo, Eliana Reyes, Victor Saavedra, Patricio Sanhueza, Pablo Sepulveda, Carmen Lia Solis, Nestor Soto, Claudia Torres, Bernhard Westerberg, Mario Yañez, Li Chen, Yugang Dong, Jianling Du, Xiaohui Guo, Ping Han, Taohong Hu, Bin Jiang, Yuannan Ke, Zhanquan Li, Juming Lu, Changsheng Ma, Yongde Peng, Yongquan Shi, Guohai Su, Baopeng Tang, Biao Xu, Jiefu Yang, Jinkui Yang, Yanmin Yang, Jose Luis Accini, Juan Manuel Arteaga, Rodrigo Botero, Gilberto Castillo, Julian Coronel, Carlos Cure, Henry Garcia, Luis Garcia, Claudia Gomez, Eric Hernandez Triana, Hector Hernandez, Monica Lopez, Patricio Lopez, Fernando Manzur, Dora Molina, Jaime Rodriguez, Gregorio Sanchez Vallejo, Hernan Yupanqui, Jens Bronnum-Schou, Peter Kaiser Nielsen, Henrik Nielsen, Henning Rønne, Soeren Rasmussen, Jørgen Rungby, Knud Skagen, Kristian Korsgaard Thomsen, Christian Torp-Pedersen, Yan Duarte-Vera, Ricardo Marmol Alvear, Carlos Peñaherrera-Patiño, Samir Assaad, Salah Shelbaya, Anu Ambos, Ulle Jakovlev, Maire Lubi, Kaja Märtsin, Svea Rosenthal, Hella Vides, Juha Alanko, Pirkko Korsoff, Anna Mari Koski, Jorma Lahtela, Lassi Nelimarkka, Jaakko Tuomilehto, Bertrand Cariou, Bogdan Catargi, Roxane Ducloux, Samy Hadjadj, Veronique Kerlan, Jean Marc Malecot, Catherine Petit, Michel Rodier, Vakhtang Chumburidze, Salome Glonti, Zaza Lominadze, Fridon Todua, Christel Contzen, Cornelia Marck, Hermann Fischer, Andreas Hagenow, Agnes Himpel-Bönninghoff, Lars Kihm, Holger Killat, Klaus Kleinertz, Christine Kosch, Kristin Kreutzmann, Mariola Lappo, Bernardo Mertes, Richard Piechatzek, Martin Prohaska, Andrea Rinke, Detlev Schellenberg, Nicole Toursarkissian, Juan Arango, Ronaldo Gonzalez, Arnoldo Granados, Milton Herrera, Pablo Montenegro, Ricardo Munoz, Edgar Rodriguez, Erick Turcios, Renato Villalobos, Fernando Wyss, Sanjay Hatterjee, Manoj Chopda, Vijay Chopra, Neeta Deshpande, R. Dutta, Sudhanshu Dwivedi, Pramod Gandhi, Sandeep Kumar Gupta, Jugal Bihari Gupta, Sunil Gupta, Narendra Hiregouder, Sujeet Jha, Abhijeet Joshi, Noor Khan, Mukund Kumbla, Mohan Magdum, Keshava Murthy, Mukhya Prabhu, Rakesh Sahay, Selvamani Sethuraman, Navneet Shah, Paramesh Shamanna, K. Singh Singh, Paminder Singh, Arun Somasekharan, Lakshminarayanappa Sreenivasamurthy, Pravin Supe, Faiad Adawi, Shaul Atar, Ohad Cohen, Shai Efrati, Eddy Karnieli, Eliezer Klainman, Oscar Minuchin, Ofri Mosenzon, Naftali Stern, Yoav Turgeman, Julio Wainstein, Gianluca Aimaretti, Cesare Berra, Anna Vittoria Ciardullo, Agostino Consoli, Domenico Cucinotta, Sandra Di Marco, Carlo Giorda, Carla Giordano, Edoardo Mannucci, Emanuela Orsi, Piermarco Piatti, Antonio Pontiroli, Paola Ponzani, Paolo Pozzilli, Angela Rivellese, Hiroshi Akahori, Yutaka Eki, Kenshi Fujii, Yoshiki Hata, Hideo Himeno, Atsushi Hirayama, Ichiro Kishimoto, Youichi Kobayashi, Hiroaki Miyaoka, Tetsuji Niiya, Yutaro Nishi, Akira Nozaki, Tatsuya Nunohiro, Tomiyoshi Saito, Yasuhiro Satoh, Akihiko Takahashi, Junichiro Takahashi, Hiroyuki Takase, Shinichi Takase, Yusuke Tsuboko, Mitsuru Tsujimoto, Motoyoshi Tsujino, Masahiro Tsuzuki, Shuichi Watanabe, Takahisa Yamada, Wook Jin Chung, Sejoong Rim, Hakchul Jang, Ung Kim, Choon Hee Chung, Sung Hee Shin, Kyehun Kim, Jaetaek Kim, Seungwoon Rha, Nae Hee Lee, Chong Jin Kim, Kyong Soo Park, Ildze Amolina, Kristine Ducena, Renate Helda, Ilze Konrade, Valdis Pirags, Iveta Sime, Jelena Sokolova, Vaida Kakariekiene, Roma Kavaliauskiene, Zaneta Petrulioniene, Gintare Sakalyte, Audrone Urboniene, Rima Zarankiene, Marittza Uribe, Pedro Garcia-Hernandez, Jose Garza, Abraham Vazquez-Garcia, Jose Gerardo Gonzalez, Miguel Escalante, Alejandro Zavala, Edmundo Bayram, Jesus Hernandez-Muñuzuri, Ramos, Gabriel Arturo Lopez, Jesus Lujan, Martin Garcia-Soria, Raul Velasco-Sanchez, Ignacio Rodriguez, Silvia Jimenez, Cielmar Galeana, Eduardo Reyes, Susano Lara, Armando Garcia-Castillo, Maria Guadalupe Castro, Raul Aguilar-Orozco, Enrique Lopez Rosas, Maricela Vidrio, Guillermo Llamas, Carlos Alejandro Stobschinski De Alba, Jaime Carranza-Madrigal, Francisco Cardosa-Torres, Jan Hein Cornel, Paulus Dekkers, J. Frederiks, Wrm Hermans, Dirk Lok, Joan Meeder, Peter Nierop, John Cooper, Knut Tore Lappegård, Bjørn Gunnar Nedrebø, Eholo Castro, Baldomero Gonzalez Castillo, Elis Gonzalez, Ruben Nieto Ortega, Miguel Andrade, Jorge Calderon, Carlos Chavez, Roger Martin Correa Flores, Julio Farfan, Libia Lu, Edith Luque, Helard Manrique, Walter Mogrovejo, Marcos Pariona-Javier, Miguel Pinto, Yudy Roldan, Carlos Zubiate, Antonio Dans, Maria Honolina Gomez, Araceli Panelo, Nannette Rey, Dennis Jose Sulit, Rosa Allyn Sy, Miriam Timonera, Janusz Bednarski, Renata Bijata-Bronisz, Leszek Bryniarski, Benita Busz-Papiez, Eugenia Czajkowska-Kaczmarek, Anna Drzewiecka, Elzbieta Dulak, Maria Gorska, Maciej Hamankiewicz, Krzysztof Janik, Krzysztof Kincel, Marek Konieczny, Andrzej Lubinski, Magdalena Olszanecka-Glinianowicz, Piotr Ponikowski, Grazyna Pulka, Jerzy Rekosz, Dariusz Skudlarski, Katarzyna Szymkowiak, Przemyslaw Wilczewski, Nuno Bragança, João Duarte, Pedro Monteiro, Elisabete Rodrigues, Margarida Vinhas, Pop Moldovan Adina, Rodica Ioana Avram, Adriana Cif, Gabriela Creteanu, Dinu Dragomir, Ioana Emilia Ferariu, Adrian Corneliu Iancu, Octavian Istratoaie, Gabriel Ivanica, Radu Lichiardopol, Constantin Militaru, Bogdan Minescu, Adriana Onaca, Ella Pintilei, Cristian Podoleanu, Lavinia Pop, Bogdan Popa, Aurelian Emil Ranetti, Doina Rosu, Adrian Tase, Dan Nicolae Tesloianu, Dragos Vinereanu, Fail Ageev, Nadir Akhmedzhanov, Olga Barbarash, Vladimir Barbarich, Yury Belousov, Svetlana Berns, Igor Bokarev, Olga Bolshakova, Mikhail Boyarkin, Galina Chumakova, Platonov Dmitry, Sergey Fitilev, Albert Galyavich, Maria Glezer, Luidmila Ivanova, Victor Kalashnikov, Marina Kalashnikova, Yuri Karpov, Larisa Khaisheva, Yuri Khalimov, Zhanna Kobalava, Elena Kosmachova, Victor Kostenko, Natalya Koziolova, Elena Kulibaba, Victor Lesnov, Igor Libov, Nadezhda Lyamina, Valentin Markov, Valentin Moiseev, Olga Molchanova, Valentin Oleynikov, Olga Orlikova, Alexey Panov, Vladimir Rafalskiy, Tatiana Rodionova, Vasily Samitin, Vladimir Schokotov, Nataliya Shilkina, Zaur Shogenov, Sergey Shustov, Yuri Shvarts, Konstantin Sobolev, Raisa Stryuk, Ludmila Suplotova, Inna Viktorova, Alexander Vishnevsky, Natalia Vorokhobina, Vladimir Yakusevich, Sergey Yakushin, Vladimir Zadionchenko, Alsu Zalevskaya, Grigory Zalevsky, Anna Zateyshchikova, Marina Andjelic Jelic, Radivoj Kocic, Snezana Komnenovic, Katarina Lalic, Nebojsa Lalic, Dragan Micic, Petar Otasevic, Milica Pesic, Petar Seferovic, Goran Stankovic, Susan Arnold, Lesley Burgess, Kathleen Coetzee, Saleem Dawood, Eluned Delport, I. Ebrahim, Graham Ellis, Siddique Ismail, Dudley Kelbe, Visvakuren Naidoo, Mpiko Ntsekhe, Peter John Sebastian, Mirna Siebert, Louis Van Zyl, Tjaart Venter, Elena Lonso, Isabel Antorrena, Vicent Bodi, Marta Botella, Javier De La Fuente, Elias Delgado, Santiago Duran Garcia, Jose Elorza, Fidel Enciso, Sonia Gaztambide, Francisco Marin, Victoria Martin, Didac Mauricio, Alfonso Soto, Manuel Vida, Gunnar Boberg, Gun Jörneskog, Johan Jendle, Ulrik Mathiesen, Karl Axel Svensson, Ingemar Torstensson, Peter Vasko, Tiziano Moccetti, Chern En Chiang, Yu Wei Chiu, Tsuei Yuan Huang, Chieh Hsiang Lu, Dee Pei, Kou Gi Shyu, Kwo Chang Ueng, Tzung Dau Wang, Mohamed Abid, Nejib Ben Abdallah, Habib Haouala, Hedia Slimane, Borni Zidi, Neslihan Bascil Tutuncu, Ahmet Camsari, Tuncay Delibasi, Nevin Dinccag, Hakan Kultursay, Ali Oto, Mahmut Sahin, Fusun Saygili, Zerrin Yigit, Cafer Zorkun, Oleksandr Karpenko, Vadym Korpachev, Olena Koval, Vitaliy Maslyanko, Mykhaylo Perepelytsya, Tetyana Pertseva, Olena Petrosyan, Leonid Rudenko, Oleg Sychov, Volodymyr Synenko, Vira Tseluyko, Larisa Zhuravleva, Wael Al Mahmeed, Ghaida Mohamad Kaddaha, Robert Andrews, Stephen Bain, Ambar Basu, Deepak Bhatnagar, Alex Bickerton, Duncan Browne, Martin Gibson, Peter Hammond, Fahmy Hanna, Basil Issa, Alan Jaap, Franklin Joseph, Edward Jude, Chris Kelly, Atir Khan, Rayaz Malik, Babu Mukhopadhyay, M. O'Kane, Gerry Rayman, Anthony Robinson, Desmond Rooney, Chris Sainsbury, Ponnusamy Saravanan, Jayadave Shakher, Baldev Singh, Jeremy Turner, Donald Whitelaw, John Wilding, Philip Wiles, Babafemi Adenuga, Zia Ahmad, Olakunle Akinboboye, Laura Akright, Paul Alappat, Mohamad Alawad, Teresa Alfonso, Ramin Alimard, Opada Alzohaili, Mehrdad Ariani, Chander Arora, Nasrin Azad, Samir Azzam, Sabrina Benjamin, Bradley Block, Eliza Borzadek, Warren Breisblatt, Tamis Bright, Leroy Byrd, Choyen Chiou, Ronald Chochinov, Tom Christensen, Elena Christofides, Robert Cohen, Gamil Dawood, Jose De Souza, Michael Dempsey, Donald Eagerton, Cara East, Charles Elder, Ronald Fernando, Leon Fogelfeld, Jean Foucauld, William French, Mary Frohnauer, Mary Gaffney, Subroto Gangopadhyay, Harinder Gogia, Aidar Gosmanov, Craig Greenberg, Frank Greenway, Edward Hanna, Joe Hargrove, Anthony Harris, Bill Harris, Terence Hart, David Herrington, Mitzie Hewitt, David Howard, Kenneth Izuora, Preetham Jetty, Anoop Kapoor, Joseph F. Kasper, Shaun Kelehan, Richard Kelly, Dean Kereiakes, Ajit Khaira, Misal Khan, Salman Khan, Elie Korban, Mikhail Kosiborod, Jacques Laguerre, James Larocque, Kashif Latif, Frank Lester, Philip Levin, Steven Levine, Charles Li, Charles Lovell, Steven Lupovitch, Ivy Joan Madu, Vahid Mahabadi, Asif Mahmood, Stavros Maragos, Cary Mariash, Paul Martin, James Mathew, John Mathew, Michael May, Ronald Mayfield, Anthony McCall, Clayton Mcdaniel, Frank Mcgrew, Marcus Mckenzie, Ivan Mefford, Arvind Mehta, Ghiath Mikdadi, Magdy Mikhail, Travis Monchamp, Charles Moore, Michael Moran, Nidal Morrar, Jonathan Mosley, Mim Mulford, John Murray, Samer Nakhle, Mani Nallasivan, Alberto Odio, Charles Oh, Sarah Olelewe, Bryce Palchick, Yogesh Paliwal, Vasilios Papademetriou, Naresh Parikh, Sudhirkumar Patel, Lawrence Phillips, Thomas Pitts, Francisco Prieto, Rachel Puttnam, Arshed Quyyumi, Preet Randhawa, Marc Rendell, Francis Rhie, James Roberts, Jerome Robinson, Michael Robinson, John Rubino, Eugene Ryan, Steven Saathoff, Isaac Sachmechi, Ali Saifi, Abraham Salacata, Robyn Sanders, Jodi Sanson, Virginia Savin, Alex Schabauer, John Schmedtje, Alan Schwartz, Cranford Scott, Munni Selagamsetty, Michael Shannon, Sylvia Shaw, Dinesh Singal, Robert Sjoberg, Kenneth Smith, Carl Sofley, Anthony Sonn, Suzanne Sorof, Eugene Soroka, C. W. Spellman, Jeffrey Steinhoff, Damodhar Suresh, Mohammad Tahir, Robert Tanenberg, Hemant Thawani, Stephen Thomson, James Thrasher, David Trachtenbarg, Michael Trotta, Weiming Tuan, Marcel Twahirwa, Guillermo Umpierrez, Brij Vaid, Carl Vance, Thomas Wang, Alberta Warner, Henry Watson, Sandra Weber, Brian Webster, Kathleen Weindorff, Michelle Welch, James Welker, Anthony White, Lindsey White, Marcus Williams, Wen Chih Wu, Alan Wynne, Mark Yocono, Kevin Yuen

Research output: Contribution to journalArticle

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Abstract

Background: Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients with T2DM and acute coronary syndrome (ACS) have a particularly high risk of CV events. The glucagonlike peptide 1 receptor agonist, lixisenatide, improves glycemia, but its effects on CV events have not been thoroughly evaluated. Methods: ELIXA (www.clinicaltrials.gov no. NCT01147250) is a randomized, double-blind, placebo-controlled, parallelgroup, multicenter study of lixisenatide in patients with T2DM and a recent ACS event. The primary aim is to evaluate the effects of lixisenatide on CV morbidity and mortality in a population at high CV risk. The primary efficacy end point is a composite of time to CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. Data are systematically collected for safety outcomes, including hypoglycemia, pancreatitis, and malignancy. Results: Enrollment began in July 2010 and ended in August 2013; 6,068 patients from 49 countries were randomized. Of these, 69% are men and 75% are white; at baseline, the mean ± SD age was 60.3 ± 9.7 years, body mass index was 30.2 ± 5.7 kg/m2, and duration of T2DM was 9.3±8.2 years. The qualifying ACS wasamyocardial infarctionin83% and unstableangina in 17%. The study will continue until the positive adjudication of the protocol-specified number of primary CV events. Conclusion: ELIXA will be the first trial to report the safety and efficacy of a glucagon-like peptide 1 receptor agonist in people with T2DM and high CV event risk.

Original languageEnglish
Pages (from-to)631-638.e7
JournalAmerican Heart Journal
Volume169
Issue number5
DOIs
StatePublished - May 1 2015
Externally publishedYes

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Acute Coronary Syndrome
Type 2 Diabetes Mellitus
Placebos
Morbidity
Safety
Peptide Receptors
Mortality
Unstable Angina
Hypoglycemia
Pancreatitis
Multicenter Studies
Hospitalization
Body Mass Index
Cardiovascular Diseases
Stroke
Myocardial Infarction
ZP10A peptide
Population
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Cardiology and Cardiovascular Medicine

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Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo. / Bentley-Lewis, Rhonda; Aguilar, David; Riddle, Matthew C.; Claggett, Brian; Diaz, Rafael; Dickstein, Kenneth; Gerstein, Hertzel C.; Johnston, Peter; Køber, Lars V.; Lawson, Francesca; Lewis, Eldrin F.; Maggioni, Aldo P.; McMurray, John J V; Ping, Lin; Probstfield, Jeffrey L.; Solomon, Scott D.; Tardif, Jean Claude; Wu, Yujun; Pfeffer, Marc A.; Barkoudah, Ebrahim; Brahimi, Abdel; Charytan, David; Finn, Peter; Flynn, Aiden; Hartley, L. Howard; Henderson, Galen; Joseph, Jacob; Odutayo, Kayode; Rajesh, Vinutha; Vazir, Ali; Weinrauch, Larry; Del Prato, Stefano; Petrie, John; Kaplan, Allen; Lieberman, Phil; Zuraw, Bruce L.; O'Reilly, Eileen; Patel, Keyur; Allen, Peter; Scarpa, Aldo; Schattner, Mark; Granger, Christopher; Rouleau, Jean; DeMets, David; Chaturvedi, Nishi; Raccah, Denis; Aizenberg, Diego; Alvarez, Carlos; Alvarisqueta, Andres; Baccaro, Claudia; Bartolacci, Ines; Bordonava, Anselmo; Bustamante Labarta, Miguel; Caccavo, Alberto; Calella, Pedro; Cantero, Maria; Codutti, Renzo; Commendatore, Victor; Costamagna, Osvaldo; Cuello, Jose; Fernandez, Alberto; Garcia Duran, Ruben; Gomez Vilamajo, Oscar; Gorban De Lapertosa, Silvia; Grinfeld, Diego; Hermida, Sonia; Lagrutta, Mariana; Leon De La Fuente, Ricardo; Licheri, Alberto; Luciardi, Hector; Mackinnon, Ignacio; Maffei, Laura; Marino, Javier; Montaña, Oscar; Novaretto, Leonardo; Orio, Silvia; Orlandini, Andres; Oviedo, Alejandra; Pérez Manghi, Federico; Patocchi, Cristian; Ramos, Hugo; Rolandi, Florencia; Saa Zarandon, Raquel; Saavedra, Silvia Salome; Schiavi, Lilia; Schygiel, Pablo; Trivi, Marcelo; Ulla, Maria; Urdiales, Pedro; Vallejos, Julio; Vico, Marisa; Waisman, Florencia; Amerena, John; Paul, Vincent; Sangla, Kunwarjit; Van Gaal, William; Yeap, Bu; Fasching, Peter; Pieber, Thomas; Danilova, Larisa; Mitkovskaya, Natalya; Sudzhaeva, Svetlana; Mathieu, Chantal; Pouleur, Anne Catherine; Botelho, Roberto Vieira; Cerqueira, Maria Jose; Chacra, Antonio; Dos Santos, Fabio; Feitosa, Gilson; Forti, Adriana; Golbert, Milton; Halpern, Alfredo; Hissa, Miguel; Lisboa, Hugo; Moraes, Joao; Nery, Max; Quadros, Alexandre; Raduan, Roberto; Reis, Gilmar; Ribeiro Filho, Fernando; Rollin, Guilherme; Rossi, Paulo; Santos, Elizabete; Sgarbi, Jose; Souza, Juliana; Souza, Maria Regina; Delchev, Alexy; Ivanov, Valentin; Klyuchkova, Neli; Kyoleyan, Michael; Levterov, Georgi; Lucheva, Mariya; Raev, Dimitar; Shumkova, Rositsa; Tokmakova, Mariya; Tzekova, Maria; Yordanov, Viktor; Bailey, Gordon; Bertrand, Olivier; Bhargava, Rakesh; Burton, Jeffrey; Campeau, Jean; Dumas, Richard; Filteau, Pierre; Syan, Gurcharan; Syan, Rajinder; Tsoukas, George; Warnica, James Wayne; Acuña, Silvia; Araneda, Guillermo; Bunster, Lia; Cobos, Leonardo; Corbalán, Ramón; Dussaillant, Gaston; Eggers, German; Florenzano, Fernando; Godoy, Gonzalo; Huidobro, Laura Andrea; Lahsen, Rodolfo; Lanas, Fernando; Larenas, Gladys; Manriquez, Leopoldo; Medina, Marcelo; Palma, Juan Carlos; Perez, Luis; Potthoff, Sergio; Raffo, Carlos; Reyes, Eliana; Saavedra, Victor; Sanhueza, Patricio; Sepulveda, Pablo; Solis, Carmen Lia; Soto, Nestor; Torres, Claudia; Westerberg, Bernhard; Yañez, Mario; Chen, Li; Dong, Yugang; Du, Jianling; Guo, Xiaohui; Han, Ping; Hu, Taohong; Jiang, Bin; Ke, Yuannan; Li, Zhanquan; Lu, Juming; Ma, Changsheng; Peng, Yongde; Shi, Yongquan; Su, Guohai; Tang, Baopeng; Xu, Biao; Yang, Jiefu; Yang, Jinkui; Yang, Yanmin; Accini, Jose Luis; Arteaga, Juan Manuel; Botero, Rodrigo; Castillo, Gilberto; Coronel, Julian; Cure, Carlos; Garcia, Henry; Garcia, Luis; Gomez, Claudia; Hernandez Triana, Eric; Hernandez, Hector; Lopez, Monica; Lopez, Patricio; Manzur, Fernando; Molina, Dora; Rodriguez, Jaime; Sanchez Vallejo, Gregorio; Yupanqui, Hernan; Bronnum-Schou, Jens; Kaiser Nielsen, Peter; Nielsen, Henrik; Rønne, Henning; Rasmussen, Soeren; Rungby, Jørgen; Skagen, Knud; Thomsen, Kristian Korsgaard; Torp-Pedersen, Christian; Duarte-Vera, Yan; Marmol Alvear, Ricardo; Peñaherrera-Patiño, Carlos; Assaad, Samir; Shelbaya, Salah; Ambos, Anu; Jakovlev, Ulle; Lubi, Maire; Märtsin, Kaja; Rosenthal, Svea; Vides, Hella; Alanko, Juha; Korsoff, Pirkko; Koski, Anna Mari; Lahtela, Jorma; Nelimarkka, Lassi; Tuomilehto, Jaakko; Cariou, Bertrand; Catargi, Bogdan; Ducloux, Roxane; Hadjadj, Samy; Kerlan, Veronique; Malecot, Jean Marc; Petit, Catherine; Rodier, Michel; Chumburidze, Vakhtang; Glonti, Salome; Lominadze, Zaza; Todua, Fridon; Contzen, Christel; Marck, Cornelia; Fischer, Hermann; Hagenow, Andreas; Himpel-Bönninghoff, Agnes; Kihm, Lars; Killat, Holger; Kleinertz, Klaus; Kosch, Christine; Kreutzmann, Kristin; Lappo, Mariola; Mertes, Bernardo; Piechatzek, Richard; Prohaska, Martin; Rinke, Andrea; Schellenberg, Detlev; Toursarkissian, Nicole; Arango, Juan; Gonzalez, Ronaldo; Granados, Arnoldo; Herrera, Milton; Montenegro, Pablo; Munoz, Ricardo; Rodriguez, Edgar; Turcios, Erick; Villalobos, Renato; Wyss, Fernando; Hatterjee, Sanjay; Chopda, Manoj; Chopra, Vijay; Deshpande, Neeta; Dutta, R.; Dwivedi, Sudhanshu; Gandhi, Pramod; Gupta, Sandeep Kumar; Gupta, Jugal Bihari; Gupta, Sunil; Hiregouder, Narendra; Jha, Sujeet; Joshi, Abhijeet; Khan, Noor; Kumbla, Mukund; Magdum, Mohan; Murthy, Keshava; Prabhu, Mukhya; Sahay, Rakesh; Sethuraman, Selvamani; Shah, Navneet; Shamanna, Paramesh; Singh, K. Singh; Singh, Paminder; Somasekharan, Arun; Sreenivasamurthy, Lakshminarayanappa; Supe, Pravin; Adawi, Faiad; Atar, Shaul; Cohen, Ohad; Efrati, Shai; Karnieli, Eddy; Klainman, Eliezer; Minuchin, Oscar; Mosenzon, Ofri; Stern, Naftali; Turgeman, Yoav; Wainstein, Julio; Aimaretti, Gianluca; Berra, Cesare; Ciardullo, Anna Vittoria; Consoli, Agostino; Cucinotta, Domenico; Di Marco, Sandra; Giorda, Carlo; Giordano, Carla; Mannucci, Edoardo; Orsi, Emanuela; Piatti, Piermarco; Pontiroli, Antonio; Ponzani, Paola; Pozzilli, Paolo; Rivellese, Angela; Akahori, Hiroshi; Eki, Yutaka; Fujii, Kenshi; Hata, Yoshiki; Himeno, Hideo; Hirayama, Atsushi; Kishimoto, Ichiro; Kobayashi, Youichi; Miyaoka, Hiroaki; Niiya, Tetsuji; Nishi, Yutaro; Nozaki, Akira; Nunohiro, Tatsuya; Saito, Tomiyoshi; Satoh, Yasuhiro; Takahashi, Akihiko; Takahashi, Junichiro; Takase, Hiroyuki; Takase, Shinichi; Tsuboko, Yusuke; Tsujimoto, Mitsuru; Tsujino, Motoyoshi; Tsuzuki, Masahiro; Watanabe, Shuichi; Yamada, Takahisa; Chung, Wook Jin; Rim, Sejoong; Jang, Hakchul; Kim, Ung; Chung, Choon Hee; Shin, Sung Hee; Kim, Kyehun; Kim, Jaetaek; Rha, Seungwoon; Lee, Nae Hee; Kim, Chong Jin; Park, Kyong Soo; Amolina, Ildze; Ducena, Kristine; Helda, Renate; Konrade, Ilze; Pirags, Valdis; Sime, Iveta; Sokolova, Jelena; Kakariekiene, Vaida; Kavaliauskiene, Roma; Petrulioniene, Zaneta; Sakalyte, Gintare; Urboniene, Audrone; Zarankiene, Rima; Uribe, Marittza; Garcia-Hernandez, Pedro; Garza, Jose; Vazquez-Garcia, Abraham; Gonzalez, Jose Gerardo; Escalante, Miguel; Zavala, Alejandro; Bayram, Edmundo; Hernandez-Muñuzuri, Jesus; Ramos; Lopez, Gabriel Arturo; Lujan, Jesus; Garcia-Soria, Martin; Velasco-Sanchez, Raul; Rodriguez, Ignacio; Jimenez, Silvia; Galeana, Cielmar; Reyes, Eduardo; Lara, Susano; Garcia-Castillo, Armando; Castro, Maria Guadalupe; Aguilar-Orozco, Raul; Lopez Rosas, Enrique; Vidrio, Maricela; Llamas, Guillermo; Stobschinski De Alba, Carlos Alejandro; Carranza-Madrigal, Jaime; Cardosa-Torres, Francisco; Cornel, Jan Hein; Dekkers, Paulus; Frederiks, J.; Hermans, Wrm; Lok, Dirk; Meeder, Joan; Nierop, Peter; Cooper, John; Lappegård, Knut Tore; Nedrebø, Bjørn Gunnar; Castro, Eholo; Gonzalez Castillo, Baldomero; Gonzalez, Elis; Nieto Ortega, Ruben; Andrade, Miguel; Calderon, Jorge; Chavez, Carlos; Correa Flores, Roger Martin; Farfan, Julio; Lu, Libia; Luque, Edith; Manrique, Helard; Mogrovejo, Walter; Pariona-Javier, Marcos; Pinto, Miguel; Roldan, Yudy; Zubiate, Carlos; Dans, Antonio; Gomez, Maria Honolina; Panelo, Araceli; Rey, Nannette; Sulit, Dennis Jose; Sy, Rosa Allyn; Timonera, Miriam; Bednarski, Janusz; Bijata-Bronisz, Renata; Bryniarski, Leszek; Busz-Papiez, Benita; Czajkowska-Kaczmarek, Eugenia; Drzewiecka, Anna; Dulak, Elzbieta; Gorska, Maria; Hamankiewicz, Maciej; Janik, Krzysztof; Kincel, Krzysztof; Konieczny, Marek; Lubinski, Andrzej; Olszanecka-Glinianowicz, Magdalena; Ponikowski, Piotr; Pulka, Grazyna; Rekosz, Jerzy; Skudlarski, Dariusz; Szymkowiak, Katarzyna; Wilczewski, Przemyslaw; Bragança, Nuno; Duarte, João; Monteiro, Pedro; Rodrigues, Elisabete; Vinhas, Margarida; Adina, Pop Moldovan; Avram, Rodica Ioana; Cif, Adriana; Creteanu, Gabriela; Dragomir, Dinu; Ferariu, Ioana Emilia; Iancu, Adrian Corneliu; Istratoaie, Octavian; Ivanica, Gabriel; Lichiardopol, Radu; Militaru, Constantin; Minescu, Bogdan; Onaca, Adriana; Pintilei, Ella; Podoleanu, Cristian; Pop, Lavinia; Popa, Bogdan; Ranetti, Aurelian Emil; Rosu, Doina; Tase, Adrian; Tesloianu, Dan Nicolae; Vinereanu, Dragos; Ageev, Fail; Akhmedzhanov, Nadir; Barbarash, Olga; Barbarich, Vladimir; Belousov, Yury; Berns, Svetlana; Bokarev, Igor; Bolshakova, Olga; Boyarkin, Mikhail; Chumakova, Galina; Dmitry, Platonov; Fitilev, Sergey; Galyavich, Albert; Glezer, Maria; Ivanova, Luidmila; Kalashnikov, Victor; Kalashnikova, Marina; Karpov, Yuri; Khaisheva, Larisa; Khalimov, Yuri; Kobalava, Zhanna; Kosmachova, Elena; Kostenko, Victor; Koziolova, Natalya; Kulibaba, Elena; Lesnov, Victor; Libov, Igor; Lyamina, Nadezhda; Markov, Valentin; Moiseev, Valentin; Molchanova, Olga; Oleynikov, Valentin; Orlikova, Olga; Panov, Alexey; Rafalskiy, Vladimir; Rodionova, Tatiana; Samitin, Vasily; Schokotov, Vladimir; Shilkina, Nataliya; Shogenov, Zaur; Shustov, Sergey; Shvarts, Yuri; Sobolev, Konstantin; Stryuk, Raisa; Suplotova, Ludmila; Viktorova, Inna; Vishnevsky, Alexander; Vorokhobina, Natalia; Yakusevich, Vladimir; Yakushin, Sergey; Zadionchenko, Vladimir; Zalevskaya, Alsu; Zalevsky, Grigory; Zateyshchikova, Anna; Andjelic Jelic, Marina; Kocic, Radivoj; Komnenovic, Snezana; Lalic, Katarina; Lalic, Nebojsa; Micic, Dragan; Otasevic, Petar; Pesic, Milica; Seferovic, Petar; Stankovic, Goran; Arnold, Susan; Burgess, Lesley; Coetzee, Kathleen; Dawood, Saleem; Delport, Eluned; Ebrahim, I.; Ellis, Graham; Ismail, Siddique; Kelbe, Dudley; Naidoo, Visvakuren; Ntsekhe, Mpiko; Sebastian, Peter John; Siebert, Mirna; Van Zyl, Louis; Venter, Tjaart; Lonso, Elena; Antorrena, Isabel; Bodi, Vicent; Botella, Marta; De La Fuente, Javier; Delgado, Elias; Duran Garcia, Santiago; Elorza, Jose; Enciso, Fidel; Gaztambide, Sonia; Marin, Francisco; Martin, Victoria; Mauricio, Didac; Soto, Alfonso; Vida, Manuel; Boberg, Gunnar; Jörneskog, Gun; Jendle, Johan; Mathiesen, Ulrik; Svensson, Karl Axel; Torstensson, Ingemar; Vasko, Peter; Moccetti, Tiziano; Chiang, Chern En; Chiu, Yu Wei; Huang, Tsuei Yuan; Lu, Chieh Hsiang; Pei, Dee; Shyu, Kou Gi; Ueng, Kwo Chang; Wang, Tzung Dau; Abid, Mohamed; Ben Abdallah, Nejib; Haouala, Habib; Slimane, Hedia; Zidi, Borni; Bascil Tutuncu, Neslihan; Camsari, Ahmet; Delibasi, Tuncay; Dinccag, Nevin; Kultursay, Hakan; Oto, Ali; Sahin, Mahmut; Saygili, Fusun; Yigit, Zerrin; Zorkun, Cafer; Karpenko, Oleksandr; Korpachev, Vadym; Koval, Olena; Maslyanko, Vitaliy; Perepelytsya, Mykhaylo; Pertseva, Tetyana; Petrosyan, Olena; Rudenko, Leonid; Sychov, Oleg; Synenko, Volodymyr; Tseluyko, Vira; Zhuravleva, Larisa; Al Mahmeed, Wael; Kaddaha, Ghaida Mohamad; Andrews, Robert; Bain, Stephen; Basu, Ambar; Bhatnagar, Deepak; Bickerton, Alex; Browne, Duncan; Gibson, Martin; Hammond, Peter; Hanna, Fahmy; Issa, Basil; Jaap, Alan; Joseph, Franklin; Jude, Edward; Kelly, Chris; Khan, Atir; Malik, Rayaz; Mukhopadhyay, Babu; O'Kane, M.; Rayman, Gerry; Robinson, Anthony; Rooney, Desmond; Sainsbury, Chris; Saravanan, Ponnusamy; Shakher, Jayadave; Singh, Baldev; Turner, Jeremy; Whitelaw, Donald; Wilding, John; Wiles, Philip; Adenuga, Babafemi; Ahmad, Zia; Akinboboye, Olakunle; Akright, Laura; Alappat, Paul; Alawad, Mohamad; Alfonso, Teresa; Alimard, Ramin; Alzohaili, Opada; Ariani, Mehrdad; Arora, Chander; Azad, Nasrin; Azzam, Samir; Benjamin, Sabrina; Block, Bradley; Borzadek, Eliza; Breisblatt, Warren; Bright, Tamis; Byrd, Leroy; Chiou, Choyen; Chochinov, Ronald; Christensen, Tom; Christofides, Elena; Cohen, Robert; Dawood, Gamil; De Souza, Jose; Dempsey, Michael; Eagerton, Donald; East, Cara; Elder, Charles; Fernando, Ronald; Fogelfeld, Leon; Foucauld, Jean; French, William; Frohnauer, Mary; Gaffney, Mary; Gangopadhyay, Subroto; Gogia, Harinder; Gosmanov, Aidar; Greenberg, Craig; Greenway, Frank; Hanna, Edward; Hargrove, Joe; Harris, Anthony; Harris, Bill; Hart, Terence; Herrington, David; Hewitt, Mitzie; Howard, David; Izuora, Kenneth; Jetty, Preetham; Kapoor, Anoop; Kasper, Joseph F.; Kelehan, Shaun; Kelly, Richard; Kereiakes, Dean; Khaira, Ajit; Khan, Misal; Khan, Salman; Korban, Elie; Kosiborod, Mikhail; Laguerre, Jacques; Larocque, James; Latif, Kashif; Lester, Frank; Levin, Philip; Levine, Steven; Li, Charles; Lovell, Charles; Lupovitch, Steven; Madu, Ivy Joan; Mahabadi, Vahid; Mahmood, Asif; Maragos, Stavros; Mariash, Cary; Martin, Paul; Mathew, James; Mathew, John; May, Michael; Mayfield, Ronald; McCall, Anthony; Mcdaniel, Clayton; Mcgrew, Frank; Mckenzie, Marcus; Mefford, Ivan; Mehta, Arvind; Mikdadi, Ghiath; Mikhail, Magdy; Monchamp, Travis; Moore, Charles; Moran, Michael; Morrar, Nidal; Mosley, Jonathan; Mulford, Mim; Murray, John; Nakhle, Samer; Nallasivan, Mani; Odio, Alberto; Oh, Charles; Olelewe, Sarah; Palchick, Bryce; Paliwal, Yogesh; Papademetriou, Vasilios; Parikh, Naresh; Patel, Sudhirkumar; Phillips, Lawrence; Pitts, Thomas; Prieto, Francisco; Puttnam, Rachel; Quyyumi, Arshed; Randhawa, Preet; Rendell, Marc; Rhie, Francis; Roberts, James; Robinson, Jerome; Robinson, Michael; Rubino, John; Ryan, Eugene; Saathoff, Steven; Sachmechi, Isaac; Saifi, Ali; Salacata, Abraham; Sanders, Robyn; Sanson, Jodi; Savin, Virginia; Schabauer, Alex; Schmedtje, John; Schwartz, Alan; Scott, Cranford; Selagamsetty, Munni; Shannon, Michael; Shaw, Sylvia; Singal, Dinesh; Sjoberg, Robert; Smith, Kenneth; Sofley, Carl; Sonn, Anthony; Sorof, Suzanne; Soroka, Eugene; Spellman, C. W.; Steinhoff, Jeffrey; Suresh, Damodhar; Tahir, Mohammad; Tanenberg, Robert; Thawani, Hemant; Thomson, Stephen; Thrasher, James; Trachtenbarg, David; Trotta, Michael; Tuan, Weiming; Twahirwa, Marcel; Umpierrez, Guillermo; Vaid, Brij; Vance, Carl; Wang, Thomas; Warner, Alberta; Watson, Henry; Weber, Sandra; Webster, Brian; Weindorff, Kathleen; Welch, Michelle; Welker, James; White, Anthony; White, Lindsey; Williams, Marcus; Wu, Wen Chih; Wynne, Alan; Yocono, Mark; Yuen, Kevin.

In: American Heart Journal, Vol. 169, No. 5, 01.05.2015, p. 631-638.e7.

Research output: Contribution to journalArticle

Bentley-Lewis, R, Aguilar, D, Riddle, MC, Claggett, B, Diaz, R, Dickstein, K, Gerstein, HC, Johnston, P, Køber, LV, Lawson, F, Lewis, EF, Maggioni, AP, McMurray, JJV, Ping, L, Probstfield, JL, Solomon, SD, Tardif, JC, Wu, Y, Pfeffer, MA, Barkoudah, E, Brahimi, A, Charytan, D, Finn, P, Flynn, A, Hartley, LH, Henderson, G, Joseph, J, Odutayo, K, Rajesh, V, Vazir, A, Weinrauch, L, Del Prato, S, Petrie, J, Kaplan, A, Lieberman, P, Zuraw, BL, O'Reilly, E, Patel, K, Allen, P, Scarpa, A, Schattner, M, Granger, C, Rouleau, J, DeMets, D, Chaturvedi, N, Raccah, D, Aizenberg, D, Alvarez, C, Alvarisqueta, A, Baccaro, C, Bartolacci, I, Bordonava, A, Bustamante Labarta, M, Caccavo, A, Calella, P, Cantero, M, Codutti, R, Commendatore, V, Costamagna, O, Cuello, J, Fernandez, A, Garcia Duran, R, Gomez Vilamajo, O, Gorban De Lapertosa, S, Grinfeld, D, Hermida, S, Lagrutta, M, Leon De La Fuente, R, Licheri, A, Luciardi, H, Mackinnon, I, Maffei, L, Marino, J, Montaña, O, Novaretto, L, Orio, S, Orlandini, A, Oviedo, A, Pérez Manghi, F, Patocchi, C, Ramos, H, Rolandi, F, Saa Zarandon, R, Saavedra, SS, Schiavi, L, Schygiel, P, Trivi, M, Ulla, M, Urdiales, P, Vallejos, J, Vico, M, Waisman, F, Amerena, J, Paul, V, Sangla, K, Van Gaal, W, Yeap, B, Fasching, P, Pieber, T, Danilova, L, Mitkovskaya, N, Sudzhaeva, S, Mathieu, C, Pouleur, AC, Botelho, RV, Cerqueira, MJ, Chacra, A, Dos Santos, F, Feitosa, G, Forti, A, Golbert, M, Halpern, A, Hissa, M, Lisboa, H, Moraes, J, Nery, M, Quadros, A, Raduan, R, Reis, G, Ribeiro Filho, F, Rollin, G, Rossi, P, Santos, E, Sgarbi, J, Souza, J, Souza, MR, Delchev, A, Ivanov, V, Klyuchkova, N, Kyoleyan, M, Levterov, G, Lucheva, M, Raev, D, Shumkova, R, Tokmakova, M, Tzekova, M, Yordanov, V, Bailey, G, Bertrand, O, Bhargava, R, Burton, J, Campeau, J, Dumas, R, Filteau, P, Syan, G, Syan, R, Tsoukas, G, Warnica, JW, Acuña, S, Araneda, G, Bunster, L, Cobos, L, Corbalán, R, Dussaillant, G, Eggers, G, Florenzano, F, Godoy, G, Huidobro, LA, Lahsen, R, Lanas, F, Larenas, G, Manriquez, L, Medina, M, Palma, JC, Perez, L, Potthoff, S, Raffo, C, Reyes, E, Saavedra, V, Sanhueza, P, Sepulveda, P, Solis, CL, Soto, N, Torres, C, Westerberg, B, Yañez, M, Chen, L, Dong, Y, Du, J, Guo, X, Han, P, Hu, T, Jiang, B, Ke, Y, Li, Z, Lu, J, Ma, C, Peng, Y, Shi, Y, Su, G, Tang, B, Xu, B, Yang, J, Yang, J, Yang, Y, Accini, JL, Arteaga, JM, Botero, R, Castillo, G, Coronel, J, Cure, C, Garcia, H, Garcia, L, Gomez, C, Hernandez Triana, E, Hernandez, H, Lopez, M, Lopez, P, Manzur, F, Molina, D, Rodriguez, J, Sanchez Vallejo, G, Yupanqui, H, Bronnum-Schou, J, Kaiser Nielsen, P, Nielsen, H, Rønne, H, Rasmussen, S, Rungby, J, Skagen, K, Thomsen, KK, Torp-Pedersen, C, Duarte-Vera, Y, Marmol Alvear, R, Peñaherrera-Patiño, C, Assaad, S, Shelbaya, S, Ambos, A, Jakovlev, U, Lubi, M, Märtsin, K, Rosenthal, S, Vides, H, Alanko, J, Korsoff, P, Koski, AM, Lahtela, J, Nelimarkka, L, Tuomilehto, J, Cariou, B, Catargi, B, Ducloux, R, Hadjadj, S, Kerlan, V, Malecot, JM, Petit, C, Rodier, M, Chumburidze, V, Glonti, S, Lominadze, Z, Todua, F, Contzen, C, Marck, C, Fischer, H, Hagenow, A, Himpel-Bönninghoff, A, Kihm, L, Killat, H, Kleinertz, K, Kosch, C, Kreutzmann, K, Lappo, M, Mertes, B, Piechatzek, R, Prohaska, M, Rinke, A, Schellenberg, D, Toursarkissian, N, Arango, J, Gonzalez, R, Granados, A, Herrera, M, Montenegro, P, Munoz, R, Rodriguez, E, Turcios, E, Villalobos, R, Wyss, F, Hatterjee, S, Chopda, M, Chopra, V, Deshpande, N, Dutta, R, Dwivedi, S, Gandhi, P, Gupta, SK, Gupta, JB, Gupta, S, Hiregouder, N, Jha, S, Joshi, A, Khan, N, Kumbla, M, Magdum, M, Murthy, K, Prabhu, M, Sahay, R, Sethuraman, S, Shah, N, Shamanna, P, Singh, KS, Singh, P, Somasekharan, A, Sreenivasamurthy, L, Supe, P, Adawi, F, Atar, S, Cohen, O, Efrati, S, Karnieli, E, Klainman, E, Minuchin, O, Mosenzon, O, Stern, N, Turgeman, Y, Wainstein, J, Aimaretti, G, Berra, C, Ciardullo, AV, Consoli, A, Cucinotta, D, Di Marco, S, Giorda, C, Giordano, C, Mannucci, E, Orsi, E, Piatti, P, Pontiroli, A, Ponzani, P, Pozzilli, P, Rivellese, A, Akahori, H, Eki, Y, Fujii, K, Hata, Y, Himeno, H, Hirayama, A, Kishimoto, I, Kobayashi, Y, Miyaoka, H, Niiya, T, Nishi, Y, Nozaki, A, Nunohiro, T, Saito, T, Satoh, Y, Takahashi, A, Takahashi, J, Takase, H, Takase, S, Tsuboko, Y, Tsujimoto, M, Tsujino, M, Tsuzuki, M, Watanabe, S, Yamada, T, Chung, WJ, Rim, S, Jang, H, Kim, U, Chung, CH, Shin, SH, Kim, K, Kim, J, Rha, S, Lee, NH, Kim, CJ, Park, KS, Amolina, I, Ducena, K, Helda, R, Konrade, I, Pirags, V, Sime, I, Sokolova, J, Kakariekiene, V, Kavaliauskiene, R, Petrulioniene, Z, Sakalyte, G, Urboniene, A, Zarankiene, R, Uribe, M, Garcia-Hernandez, P, Garza, J, Vazquez-Garcia, A, Gonzalez, JG, Escalante, M, Zavala, A, Bayram, E, Hernandez-Muñuzuri, J, Ramos, Lopez, GA, Lujan, J, Garcia-Soria, M, Velasco-Sanchez, R, Rodriguez, I, Jimenez, S, Galeana, C, Reyes, E, Lara, S, Garcia-Castillo, A, Castro, MG, Aguilar-Orozco, R, Lopez Rosas, E, Vidrio, M, Llamas, G, Stobschinski De Alba, CA, Carranza-Madrigal, J, Cardosa-Torres, F, Cornel, JH, Dekkers, P, Frederiks, J, Hermans, W, Lok, D, Meeder, J, Nierop, P, Cooper, J, Lappegård, KT, Nedrebø, BG, Castro, E, Gonzalez Castillo, B, Gonzalez, E, Nieto Ortega, R, Andrade, M, Calderon, J, Chavez, C, Correa Flores, RM, Farfan, J, Lu, L, Luque, E, Manrique, H, Mogrovejo, W, Pariona-Javier, M, Pinto, M, Roldan, Y, Zubiate, C, Dans, A, Gomez, MH, Panelo, A, Rey, N, Sulit, DJ, Sy, RA, Timonera, M, Bednarski, J, Bijata-Bronisz, R, Bryniarski, L, Busz-Papiez, B, Czajkowska-Kaczmarek, E, Drzewiecka, A, Dulak, E, Gorska, M, Hamankiewicz, M, Janik, K, Kincel, K, Konieczny, M, Lubinski, A, Olszanecka-Glinianowicz, M, Ponikowski, P, Pulka, G, Rekosz, J, Skudlarski, D, Szymkowiak, K, Wilczewski, P, Bragança, N, Duarte, J, Monteiro, P, Rodrigues, E, Vinhas, M, Adina, PM, Avram, RI, Cif, A, Creteanu, G, Dragomir, D, Ferariu, IE, Iancu, AC, Istratoaie, O, Ivanica, G, Lichiardopol, R, Militaru, C, Minescu, B, Onaca, A, Pintilei, E, Podoleanu, C, Pop, L, Popa, B, Ranetti, AE, Rosu, D, Tase, A, Tesloianu, DN, Vinereanu, D, Ageev, F, Akhmedzhanov, N, Barbarash, O, Barbarich, V, Belousov, Y, Berns, S, Bokarev, I, Bolshakova, O, Boyarkin, M, Chumakova, G, Dmitry, P, Fitilev, S, Galyavich, A, Glezer, M, Ivanova, L, Kalashnikov, V, Kalashnikova, M, Karpov, Y, Khaisheva, L, Khalimov, Y, Kobalava, Z, Kosmachova, E, Kostenko, V, Koziolova, N, Kulibaba, E, Lesnov, V, Libov, I, Lyamina, N, Markov, V, Moiseev, V, Molchanova, O, Oleynikov, V, Orlikova, O, Panov, A, Rafalskiy, V, Rodionova, T, Samitin, V, Schokotov, V, Shilkina, N, Shogenov, Z, Shustov, S, Shvarts, Y, Sobolev, K, Stryuk, R, Suplotova, L, Viktorova, I, Vishnevsky, A, Vorokhobina, N, Yakusevich, V, Yakushin, S, Zadionchenko, V, Zalevskaya, A, Zalevsky, G, Zateyshchikova, A, Andjelic Jelic, M, Kocic, R, Komnenovic, S, Lalic, K, Lalic, N, Micic, D, Otasevic, P, Pesic, M, Seferovic, P, Stankovic, G, Arnold, S, Burgess, L, Coetzee, K, Dawood, S, Delport, E, Ebrahim, I, Ellis, G, Ismail, S, Kelbe, D, Naidoo, V, Ntsekhe, M, Sebastian, PJ, Siebert, M, Van Zyl, L, Venter, T, Lonso, E, Antorrena, I, Bodi, V, Botella, M, De La Fuente, J, Delgado, E, Duran Garcia, S, Elorza, J, Enciso, F, Gaztambide, S, Marin, F, Martin, V, Mauricio, D, Soto, A, Vida, M, Boberg, G, Jörneskog, G, Jendle, J, Mathiesen, U, Svensson, KA, Torstensson, I, Vasko, P, Moccetti, T, Chiang, CE, Chiu, YW, Huang, TY, Lu, CH, Pei, D, Shyu, KG, Ueng, KC, Wang, TD, Abid, M, Ben Abdallah, N, Haouala, H, Slimane, H, Zidi, B, Bascil Tutuncu, N, Camsari, A, Delibasi, T, Dinccag, N, Kultursay, H, Oto, A, Sahin, M, Saygili, F, Yigit, Z, Zorkun, C, Karpenko, O, Korpachev, V, Koval, O, Maslyanko, V, Perepelytsya, M, Pertseva, T, Petrosyan, O, Rudenko, L, Sychov, O, Synenko, V, Tseluyko, V, Zhuravleva, L, Al Mahmeed, W, Kaddaha, GM, Andrews, R, Bain, S, Basu, A, Bhatnagar, D, Bickerton, A, Browne, D, Gibson, M, Hammond, P, Hanna, F, Issa, B, Jaap, A, Joseph, F, Jude, E, Kelly, C, Khan, A, Malik, R, Mukhopadhyay, B, O'Kane, M, Rayman, G, Robinson, A, Rooney, D, Sainsbury, C, Saravanan, P, Shakher, J, Singh, B, Turner, J, Whitelaw, D, Wilding, J, Wiles, P, Adenuga, B, Ahmad, Z, Akinboboye, O, Akright, L, Alappat, P, Alawad, M, Alfonso, T, Alimard, R, Alzohaili, O, Ariani, M, Arora, C, Azad, N, Azzam, S, Benjamin, S, Block, B, Borzadek, E, Breisblatt, W, Bright, T, Byrd, L, Chiou, C, Chochinov, R, Christensen, T, Christofides, E, Cohen, R, Dawood, G, De Souza, J, Dempsey, M, Eagerton, D, East, C, Elder, C, Fernando, R, Fogelfeld, L, Foucauld, J, French, W, Frohnauer, M, Gaffney, M, Gangopadhyay, S, Gogia, H, Gosmanov, A, Greenberg, C, Greenway, F, Hanna, E, Hargrove, J, Harris, A, Harris, B, Hart, T, Herrington, D, Hewitt, M, Howard, D, Izuora, K, Jetty, P, Kapoor, A, Kasper, JF, Kelehan, S, Kelly, R, Kereiakes, D, Khaira, A, Khan, M, Khan, S, Korban, E, Kosiborod, M, Laguerre, J, Larocque, J, Latif, K, Lester, F, Levin, P, Levine, S, Li, C, Lovell, C, Lupovitch, S, Madu, IJ, Mahabadi, V, Mahmood, A, Maragos, S, Mariash, C, Martin, P, Mathew, J, Mathew, J, May, M, Mayfield, R, McCall, A, Mcdaniel, C, Mcgrew, F, Mckenzie, M, Mefford, I, Mehta, A, Mikdadi, G, Mikhail, M, Monchamp, T, Moore, C, Moran, M, Morrar, N, Mosley, J, Mulford, M, Murray, J, Nakhle, S, Nallasivan, M, Odio, A, Oh, C, Olelewe, S, Palchick, B, Paliwal, Y, Papademetriou, V, Parikh, N, Patel, S, Phillips, L, Pitts, T, Prieto, F, Puttnam, R, Quyyumi, A, Randhawa, P, Rendell, M, Rhie, F, Roberts, J, Robinson, J, Robinson, M, Rubino, J, Ryan, E, Saathoff, S, Sachmechi, I, Saifi, A, Salacata, A, Sanders, R, Sanson, J, Savin, V, Schabauer, A, Schmedtje, J, Schwartz, A, Scott, C, Selagamsetty, M, Shannon, M, Shaw, S, Singal, D, Sjoberg, R, Smith, K, Sofley, C, Sonn, A, Sorof, S, Soroka, E, Spellman, CW, Steinhoff, J, Suresh, D, Tahir, M, Tanenberg, R, Thawani, H, Thomson, S, Thrasher, J, Trachtenbarg, D, Trotta, M, Tuan, W, Twahirwa, M, Umpierrez, G, Vaid, B, Vance, C, Wang, T, Warner, A, Watson, H, Weber, S, Webster, B, Weindorff, K, Welch, M, Welker, J, White, A, White, L, Williams, M, Wu, WC, Wynne, A, Yocono, M & Yuen, K 2015, 'Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo', American Heart Journal, vol. 169, no. 5, pp. 631-638.e7. https://doi.org/10.1016/j.ahj.2015.02.002
Bentley-Lewis, Rhonda ; Aguilar, David ; Riddle, Matthew C. ; Claggett, Brian ; Diaz, Rafael ; Dickstein, Kenneth ; Gerstein, Hertzel C. ; Johnston, Peter ; Køber, Lars V. ; Lawson, Francesca ; Lewis, Eldrin F. ; Maggioni, Aldo P. ; McMurray, John J V ; Ping, Lin ; Probstfield, Jeffrey L. ; Solomon, Scott D. ; Tardif, Jean Claude ; Wu, Yujun ; Pfeffer, Marc A. ; Barkoudah, Ebrahim ; Brahimi, Abdel ; Charytan, David ; Finn, Peter ; Flynn, Aiden ; Hartley, L. Howard ; Henderson, Galen ; Joseph, Jacob ; Odutayo, Kayode ; Rajesh, Vinutha ; Vazir, Ali ; Weinrauch, Larry ; Del Prato, Stefano ; Petrie, John ; Kaplan, Allen ; Lieberman, Phil ; Zuraw, Bruce L. ; O'Reilly, Eileen ; Patel, Keyur ; Allen, Peter ; Scarpa, Aldo ; Schattner, Mark ; Granger, Christopher ; Rouleau, Jean ; DeMets, David ; Chaturvedi, Nishi ; Raccah, Denis ; Aizenberg, Diego ; Alvarez, Carlos ; Alvarisqueta, Andres ; Baccaro, Claudia ; Bartolacci, Ines ; Bordonava, Anselmo ; Bustamante Labarta, Miguel ; Caccavo, Alberto ; Calella, Pedro ; Cantero, Maria ; Codutti, Renzo ; Commendatore, Victor ; Costamagna, Osvaldo ; Cuello, Jose ; Fernandez, Alberto ; Garcia Duran, Ruben ; Gomez Vilamajo, Oscar ; Gorban De Lapertosa, Silvia ; Grinfeld, Diego ; Hermida, Sonia ; Lagrutta, Mariana ; Leon De La Fuente, Ricardo ; Licheri, Alberto ; Luciardi, Hector ; Mackinnon, Ignacio ; Maffei, Laura ; Marino, Javier ; Montaña, Oscar ; Novaretto, Leonardo ; Orio, Silvia ; Orlandini, Andres ; Oviedo, Alejandra ; Pérez Manghi, Federico ; Patocchi, Cristian ; Ramos, Hugo ; Rolandi, Florencia ; Saa Zarandon, Raquel ; Saavedra, Silvia Salome ; Schiavi, Lilia ; Schygiel, Pablo ; Trivi, Marcelo ; Ulla, Maria ; Urdiales, Pedro ; Vallejos, Julio ; Vico, Marisa ; Waisman, Florencia ; Amerena, John ; Paul, Vincent ; Sangla, Kunwarjit ; Van Gaal, William ; Yeap, Bu ; Fasching, Peter ; Pieber, Thomas ; Danilova, Larisa ; Mitkovskaya, Natalya ; Sudzhaeva, Svetlana ; Mathieu, Chantal ; Pouleur, Anne Catherine ; Botelho, Roberto Vieira ; Cerqueira, Maria Jose ; Chacra, Antonio ; Dos Santos, Fabio ; Feitosa, Gilson ; Forti, Adriana ; Golbert, Milton ; Halpern, Alfredo ; Hissa, Miguel ; Lisboa, Hugo ; Moraes, Joao ; Nery, Max ; Quadros, Alexandre ; Raduan, Roberto ; Reis, Gilmar ; Ribeiro Filho, Fernando ; Rollin, Guilherme ; Rossi, Paulo ; Santos, Elizabete ; Sgarbi, Jose ; Souza, Juliana ; Souza, Maria Regina ; Delchev, Alexy ; Ivanov, Valentin ; Klyuchkova, Neli ; Kyoleyan, Michael ; Levterov, Georgi ; Lucheva, Mariya ; Raev, Dimitar ; Shumkova, Rositsa ; Tokmakova, Mariya ; Tzekova, Maria ; Yordanov, Viktor ; Bailey, Gordon ; Bertrand, Olivier ; Bhargava, Rakesh ; Burton, Jeffrey ; Campeau, Jean ; Dumas, Richard ; Filteau, Pierre ; Syan, Gurcharan ; Syan, Rajinder ; Tsoukas, George ; Warnica, James Wayne ; Acuña, Silvia ; Araneda, Guillermo ; Bunster, Lia ; Cobos, Leonardo ; Corbalán, Ramón ; Dussaillant, Gaston ; Eggers, German ; Florenzano, Fernando ; Godoy, Gonzalo ; Huidobro, Laura Andrea ; Lahsen, Rodolfo ; Lanas, Fernando ; Larenas, Gladys ; Manriquez, Leopoldo ; Medina, Marcelo ; Palma, Juan Carlos ; Perez, Luis ; Potthoff, Sergio ; Raffo, Carlos ; Reyes, Eliana ; Saavedra, Victor ; Sanhueza, Patricio ; Sepulveda, Pablo ; Solis, Carmen Lia ; Soto, Nestor ; Torres, Claudia ; Westerberg, Bernhard ; Yañez, Mario ; Chen, Li ; Dong, Yugang ; Du, Jianling ; Guo, Xiaohui ; Han, Ping ; Hu, Taohong ; Jiang, Bin ; Ke, Yuannan ; Li, Zhanquan ; Lu, Juming ; Ma, Changsheng ; Peng, Yongde ; Shi, Yongquan ; Su, Guohai ; Tang, Baopeng ; Xu, Biao ; Yang, Jiefu ; Yang, Jinkui ; Yang, Yanmin ; Accini, Jose Luis ; Arteaga, Juan Manuel ; Botero, Rodrigo ; Castillo, Gilberto ; Coronel, Julian ; Cure, Carlos ; Garcia, Henry ; Garcia, Luis ; Gomez, Claudia ; Hernandez Triana, Eric ; Hernandez, Hector ; Lopez, Monica ; Lopez, Patricio ; Manzur, Fernando ; Molina, Dora ; Rodriguez, Jaime ; Sanchez Vallejo, Gregorio ; Yupanqui, Hernan ; Bronnum-Schou, Jens ; Kaiser Nielsen, Peter ; Nielsen, Henrik ; Rønne, Henning ; Rasmussen, Soeren ; Rungby, Jørgen ; Skagen, Knud ; Thomsen, Kristian Korsgaard ; Torp-Pedersen, Christian ; Duarte-Vera, Yan ; Marmol Alvear, Ricardo ; Peñaherrera-Patiño, Carlos ; Assaad, Samir ; Shelbaya, Salah ; Ambos, Anu ; Jakovlev, Ulle ; Lubi, Maire ; Märtsin, Kaja ; Rosenthal, Svea ; Vides, Hella ; Alanko, Juha ; Korsoff, Pirkko ; Koski, Anna Mari ; Lahtela, Jorma ; Nelimarkka, Lassi ; Tuomilehto, Jaakko ; Cariou, Bertrand ; Catargi, Bogdan ; Ducloux, Roxane ; Hadjadj, Samy ; Kerlan, Veronique ; Malecot, Jean Marc ; Petit, Catherine ; Rodier, Michel ; Chumburidze, Vakhtang ; Glonti, Salome ; Lominadze, Zaza ; Todua, Fridon ; Contzen, Christel ; Marck, Cornelia ; Fischer, Hermann ; Hagenow, Andreas ; Himpel-Bönninghoff, Agnes ; Kihm, Lars ; Killat, Holger ; Kleinertz, Klaus ; Kosch, Christine ; Kreutzmann, Kristin ; Lappo, Mariola ; Mertes, Bernardo ; Piechatzek, Richard ; Prohaska, Martin ; Rinke, Andrea ; Schellenberg, Detlev ; Toursarkissian, Nicole ; Arango, Juan ; Gonzalez, Ronaldo ; Granados, Arnoldo ; Herrera, Milton ; Montenegro, Pablo ; Munoz, Ricardo ; Rodriguez, Edgar ; Turcios, Erick ; Villalobos, Renato ; Wyss, Fernando ; Hatterjee, Sanjay ; Chopda, Manoj ; Chopra, Vijay ; Deshpande, Neeta ; Dutta, R. ; Dwivedi, Sudhanshu ; Gandhi, Pramod ; Gupta, Sandeep Kumar ; Gupta, Jugal Bihari ; Gupta, Sunil ; Hiregouder, Narendra ; Jha, Sujeet ; Joshi, Abhijeet ; Khan, Noor ; Kumbla, Mukund ; Magdum, Mohan ; Murthy, Keshava ; Prabhu, Mukhya ; Sahay, Rakesh ; Sethuraman, Selvamani ; Shah, Navneet ; Shamanna, Paramesh ; Singh, K. Singh ; Singh, Paminder ; Somasekharan, Arun ; Sreenivasamurthy, Lakshminarayanappa ; Supe, Pravin ; Adawi, Faiad ; Atar, Shaul ; Cohen, Ohad ; Efrati, Shai ; Karnieli, Eddy ; Klainman, Eliezer ; Minuchin, Oscar ; Mosenzon, Ofri ; Stern, Naftali ; Turgeman, Yoav ; Wainstein, Julio ; Aimaretti, Gianluca ; Berra, Cesare ; Ciardullo, Anna Vittoria ; Consoli, Agostino ; Cucinotta, Domenico ; Di Marco, Sandra ; Giorda, Carlo ; Giordano, Carla ; Mannucci, Edoardo ; Orsi, Emanuela ; Piatti, Piermarco ; Pontiroli, Antonio ; Ponzani, Paola ; Pozzilli, Paolo ; Rivellese, Angela ; Akahori, Hiroshi ; Eki, Yutaka ; Fujii, Kenshi ; Hata, Yoshiki ; Himeno, Hideo ; Hirayama, Atsushi ; Kishimoto, Ichiro ; Kobayashi, Youichi ; Miyaoka, Hiroaki ; Niiya, Tetsuji ; Nishi, Yutaro ; Nozaki, Akira ; Nunohiro, Tatsuya ; Saito, Tomiyoshi ; Satoh, Yasuhiro ; Takahashi, Akihiko ; Takahashi, Junichiro ; Takase, Hiroyuki ; Takase, Shinichi ; Tsuboko, Yusuke ; Tsujimoto, Mitsuru ; Tsujino, Motoyoshi ; Tsuzuki, Masahiro ; Watanabe, Shuichi ; Yamada, Takahisa ; Chung, Wook Jin ; Rim, Sejoong ; Jang, Hakchul ; Kim, Ung ; Chung, Choon Hee ; Shin, Sung Hee ; Kim, Kyehun ; Kim, Jaetaek ; Rha, Seungwoon ; Lee, Nae Hee ; Kim, Chong Jin ; Park, Kyong Soo ; Amolina, Ildze ; Ducena, Kristine ; Helda, Renate ; Konrade, Ilze ; Pirags, Valdis ; Sime, Iveta ; Sokolova, Jelena ; Kakariekiene, Vaida ; Kavaliauskiene, Roma ; Petrulioniene, Zaneta ; Sakalyte, Gintare ; Urboniene, Audrone ; Zarankiene, Rima ; Uribe, Marittza ; Garcia-Hernandez, Pedro ; Garza, Jose ; Vazquez-Garcia, Abraham ; Gonzalez, Jose Gerardo ; Escalante, Miguel ; Zavala, Alejandro ; Bayram, Edmundo ; Hernandez-Muñuzuri, Jesus ; Ramos ; Lopez, Gabriel Arturo ; Lujan, Jesus ; Garcia-Soria, Martin ; Velasco-Sanchez, Raul ; Rodriguez, Ignacio ; Jimenez, Silvia ; Galeana, Cielmar ; Reyes, Eduardo ; Lara, Susano ; Garcia-Castillo, Armando ; Castro, Maria Guadalupe ; Aguilar-Orozco, Raul ; Lopez Rosas, Enrique ; Vidrio, Maricela ; Llamas, Guillermo ; Stobschinski De Alba, Carlos Alejandro ; Carranza-Madrigal, Jaime ; Cardosa-Torres, Francisco ; Cornel, Jan Hein ; Dekkers, Paulus ; Frederiks, J. ; Hermans, Wrm ; Lok, Dirk ; Meeder, Joan ; Nierop, Peter ; Cooper, John ; Lappegård, Knut Tore ; Nedrebø, Bjørn Gunnar ; Castro, Eholo ; Gonzalez Castillo, Baldomero ; Gonzalez, Elis ; Nieto Ortega, Ruben ; Andrade, Miguel ; Calderon, Jorge ; Chavez, Carlos ; Correa Flores, Roger Martin ; Farfan, Julio ; Lu, Libia ; Luque, Edith ; Manrique, Helard ; Mogrovejo, Walter ; Pariona-Javier, Marcos ; Pinto, Miguel ; Roldan, Yudy ; Zubiate, Carlos ; Dans, Antonio ; Gomez, Maria Honolina ; Panelo, Araceli ; Rey, Nannette ; Sulit, Dennis Jose ; Sy, Rosa Allyn ; Timonera, Miriam ; Bednarski, Janusz ; Bijata-Bronisz, Renata ; Bryniarski, Leszek ; Busz-Papiez, Benita ; Czajkowska-Kaczmarek, Eugenia ; Drzewiecka, Anna ; Dulak, Elzbieta ; Gorska, Maria ; Hamankiewicz, Maciej ; Janik, Krzysztof ; Kincel, Krzysztof ; Konieczny, Marek ; Lubinski, Andrzej ; Olszanecka-Glinianowicz, Magdalena ; Ponikowski, Piotr ; Pulka, Grazyna ; Rekosz, Jerzy ; Skudlarski, Dariusz ; Szymkowiak, Katarzyna ; Wilczewski, Przemyslaw ; Bragança, Nuno ; Duarte, João ; Monteiro, Pedro ; Rodrigues, Elisabete ; Vinhas, Margarida ; Adina, Pop Moldovan ; Avram, Rodica Ioana ; Cif, Adriana ; Creteanu, Gabriela ; Dragomir, Dinu ; Ferariu, Ioana Emilia ; Iancu, Adrian Corneliu ; Istratoaie, Octavian ; Ivanica, Gabriel ; Lichiardopol, Radu ; Militaru, Constantin ; Minescu, Bogdan ; Onaca, Adriana ; Pintilei, Ella ; Podoleanu, Cristian ; Pop, Lavinia ; Popa, Bogdan ; Ranetti, Aurelian Emil ; Rosu, Doina ; Tase, Adrian ; Tesloianu, Dan Nicolae ; Vinereanu, Dragos ; Ageev, Fail ; Akhmedzhanov, Nadir ; Barbarash, Olga ; Barbarich, Vladimir ; Belousov, Yury ; Berns, Svetlana ; Bokarev, Igor ; Bolshakova, Olga ; Boyarkin, Mikhail ; Chumakova, Galina ; Dmitry, Platonov ; Fitilev, Sergey ; Galyavich, Albert ; Glezer, Maria ; Ivanova, Luidmila ; Kalashnikov, Victor ; Kalashnikova, Marina ; Karpov, Yuri ; Khaisheva, Larisa ; Khalimov, Yuri ; Kobalava, Zhanna ; Kosmachova, Elena ; Kostenko, Victor ; Koziolova, Natalya ; Kulibaba, Elena ; Lesnov, Victor ; Libov, Igor ; Lyamina, Nadezhda ; Markov, Valentin ; Moiseev, Valentin ; Molchanova, Olga ; Oleynikov, Valentin ; Orlikova, Olga ; Panov, Alexey ; Rafalskiy, Vladimir ; Rodionova, Tatiana ; Samitin, Vasily ; Schokotov, Vladimir ; Shilkina, Nataliya ; Shogenov, Zaur ; Shustov, Sergey ; Shvarts, Yuri ; Sobolev, Konstantin ; Stryuk, Raisa ; Suplotova, Ludmila ; Viktorova, Inna ; Vishnevsky, Alexander ; Vorokhobina, Natalia ; Yakusevich, Vladimir ; Yakushin, Sergey ; Zadionchenko, Vladimir ; Zalevskaya, Alsu ; Zalevsky, Grigory ; Zateyshchikova, Anna ; Andjelic Jelic, Marina ; Kocic, Radivoj ; Komnenovic, Snezana ; Lalic, Katarina ; Lalic, Nebojsa ; Micic, Dragan ; Otasevic, Petar ; Pesic, Milica ; Seferovic, Petar ; Stankovic, Goran ; Arnold, Susan ; Burgess, Lesley ; Coetzee, Kathleen ; Dawood, Saleem ; Delport, Eluned ; Ebrahim, I. ; Ellis, Graham ; Ismail, Siddique ; Kelbe, Dudley ; Naidoo, Visvakuren ; Ntsekhe, Mpiko ; Sebastian, Peter John ; Siebert, Mirna ; Van Zyl, Louis ; Venter, Tjaart ; Lonso, Elena ; Antorrena, Isabel ; Bodi, Vicent ; Botella, Marta ; De La Fuente, Javier ; Delgado, Elias ; Duran Garcia, Santiago ; Elorza, Jose ; Enciso, Fidel ; Gaztambide, Sonia ; Marin, Francisco ; Martin, Victoria ; Mauricio, Didac ; Soto, Alfonso ; Vida, Manuel ; Boberg, Gunnar ; Jörneskog, Gun ; Jendle, Johan ; Mathiesen, Ulrik ; Svensson, Karl Axel ; Torstensson, Ingemar ; Vasko, Peter ; Moccetti, Tiziano ; Chiang, Chern En ; Chiu, Yu Wei ; Huang, Tsuei Yuan ; Lu, Chieh Hsiang ; Pei, Dee ; Shyu, Kou Gi ; Ueng, Kwo Chang ; Wang, Tzung Dau ; Abid, Mohamed ; Ben Abdallah, Nejib ; Haouala, Habib ; Slimane, Hedia ; Zidi, Borni ; Bascil Tutuncu, Neslihan ; Camsari, Ahmet ; Delibasi, Tuncay ; Dinccag, Nevin ; Kultursay, Hakan ; Oto, Ali ; Sahin, Mahmut ; Saygili, Fusun ; Yigit, Zerrin ; Zorkun, Cafer ; Karpenko, Oleksandr ; Korpachev, Vadym ; Koval, Olena ; Maslyanko, Vitaliy ; Perepelytsya, Mykhaylo ; Pertseva, Tetyana ; Petrosyan, Olena ; Rudenko, Leonid ; Sychov, Oleg ; Synenko, Volodymyr ; Tseluyko, Vira ; Zhuravleva, Larisa ; Al Mahmeed, Wael ; Kaddaha, Ghaida Mohamad ; Andrews, Robert ; Bain, Stephen ; Basu, Ambar ; Bhatnagar, Deepak ; Bickerton, Alex ; Browne, Duncan ; Gibson, Martin ; Hammond, Peter ; Hanna, Fahmy ; Issa, Basil ; Jaap, Alan ; Joseph, Franklin ; Jude, Edward ; Kelly, Chris ; Khan, Atir ; Malik, Rayaz ; Mukhopadhyay, Babu ; O'Kane, M. ; Rayman, Gerry ; Robinson, Anthony ; Rooney, Desmond ; Sainsbury, Chris ; Saravanan, Ponnusamy ; Shakher, Jayadave ; Singh, Baldev ; Turner, Jeremy ; Whitelaw, Donald ; Wilding, John ; Wiles, Philip ; Adenuga, Babafemi ; Ahmad, Zia ; Akinboboye, Olakunle ; Akright, Laura ; Alappat, Paul ; Alawad, Mohamad ; Alfonso, Teresa ; Alimard, Ramin ; Alzohaili, Opada ; Ariani, Mehrdad ; Arora, Chander ; Azad, Nasrin ; Azzam, Samir ; Benjamin, Sabrina ; Block, Bradley ; Borzadek, Eliza ; Breisblatt, Warren ; Bright, Tamis ; Byrd, Leroy ; Chiou, Choyen ; Chochinov, Ronald ; Christensen, Tom ; Christofides, Elena ; Cohen, Robert ; Dawood, Gamil ; De Souza, Jose ; Dempsey, Michael ; Eagerton, Donald ; East, Cara ; Elder, Charles ; Fernando, Ronald ; Fogelfeld, Leon ; Foucauld, Jean ; French, William ; Frohnauer, Mary ; Gaffney, Mary ; Gangopadhyay, Subroto ; Gogia, Harinder ; Gosmanov, Aidar ; Greenberg, Craig ; Greenway, Frank ; Hanna, Edward ; Hargrove, Joe ; Harris, Anthony ; Harris, Bill ; Hart, Terence ; Herrington, David ; Hewitt, Mitzie ; Howard, David ; Izuora, Kenneth ; Jetty, Preetham ; Kapoor, Anoop ; Kasper, Joseph F. ; Kelehan, Shaun ; Kelly, Richard ; Kereiakes, Dean ; Khaira, Ajit ; Khan, Misal ; Khan, Salman ; Korban, Elie ; Kosiborod, Mikhail ; Laguerre, Jacques ; Larocque, James ; Latif, Kashif ; Lester, Frank ; Levin, Philip ; Levine, Steven ; Li, Charles ; Lovell, Charles ; Lupovitch, Steven ; Madu, Ivy Joan ; Mahabadi, Vahid ; Mahmood, Asif ; Maragos, Stavros ; Mariash, Cary ; Martin, Paul ; Mathew, James ; Mathew, John ; May, Michael ; Mayfield, Ronald ; McCall, Anthony ; Mcdaniel, Clayton ; Mcgrew, Frank ; Mckenzie, Marcus ; Mefford, Ivan ; Mehta, Arvind ; Mikdadi, Ghiath ; Mikhail, Magdy ; Monchamp, Travis ; Moore, Charles ; Moran, Michael ; Morrar, Nidal ; Mosley, Jonathan ; Mulford, Mim ; Murray, John ; Nakhle, Samer ; Nallasivan, Mani ; Odio, Alberto ; Oh, Charles ; Olelewe, Sarah ; Palchick, Bryce ; Paliwal, Yogesh ; Papademetriou, Vasilios ; Parikh, Naresh ; Patel, Sudhirkumar ; Phillips, Lawrence ; Pitts, Thomas ; Prieto, Francisco ; Puttnam, Rachel ; Quyyumi, Arshed ; Randhawa, Preet ; Rendell, Marc ; Rhie, Francis ; Roberts, James ; Robinson, Jerome ; Robinson, Michael ; Rubino, John ; Ryan, Eugene ; Saathoff, Steven ; Sachmechi, Isaac ; Saifi, Ali ; Salacata, Abraham ; Sanders, Robyn ; Sanson, Jodi ; Savin, Virginia ; Schabauer, Alex ; Schmedtje, John ; Schwartz, Alan ; Scott, Cranford ; Selagamsetty, Munni ; Shannon, Michael ; Shaw, Sylvia ; Singal, Dinesh ; Sjoberg, Robert ; Smith, Kenneth ; Sofley, Carl ; Sonn, Anthony ; Sorof, Suzanne ; Soroka, Eugene ; Spellman, C. W. ; Steinhoff, Jeffrey ; Suresh, Damodhar ; Tahir, Mohammad ; Tanenberg, Robert ; Thawani, Hemant ; Thomson, Stephen ; Thrasher, James ; Trachtenbarg, David ; Trotta, Michael ; Tuan, Weiming ; Twahirwa, Marcel ; Umpierrez, Guillermo ; Vaid, Brij ; Vance, Carl ; Wang, Thomas ; Warner, Alberta ; Watson, Henry ; Weber, Sandra ; Webster, Brian ; Weindorff, Kathleen ; Welch, Michelle ; Welker, James ; White, Anthony ; White, Lindsey ; Williams, Marcus ; Wu, Wen Chih ; Wynne, Alan ; Yocono, Mark ; Yuen, Kevin. / Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo. In: American Heart Journal. 2015 ; Vol. 169, No. 5. pp. 631-638.e7.
@article{465239789d6e450d837e263c8181d3c7,
title = "Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo",
abstract = "Background: Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients with T2DM and acute coronary syndrome (ACS) have a particularly high risk of CV events. The glucagonlike peptide 1 receptor agonist, lixisenatide, improves glycemia, but its effects on CV events have not been thoroughly evaluated. Methods: ELIXA (www.clinicaltrials.gov no. NCT01147250) is a randomized, double-blind, placebo-controlled, parallelgroup, multicenter study of lixisenatide in patients with T2DM and a recent ACS event. The primary aim is to evaluate the effects of lixisenatide on CV morbidity and mortality in a population at high CV risk. The primary efficacy end point is a composite of time to CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. Data are systematically collected for safety outcomes, including hypoglycemia, pancreatitis, and malignancy. Results: Enrollment began in July 2010 and ended in August 2013; 6,068 patients from 49 countries were randomized. Of these, 69{\%} are men and 75{\%} are white; at baseline, the mean ± SD age was 60.3 ± 9.7 years, body mass index was 30.2 ± 5.7 kg/m2, and duration of T2DM was 9.3±8.2 years. The qualifying ACS wasamyocardial infarctionin83{\%} and unstableangina in 17{\%}. The study will continue until the positive adjudication of the protocol-specified number of primary CV events. Conclusion: ELIXA will be the first trial to report the safety and efficacy of a glucagon-like peptide 1 receptor agonist in people with T2DM and high CV event risk.",
author = "Rhonda Bentley-Lewis and David Aguilar and Riddle, {Matthew C.} and Brian Claggett and Rafael Diaz and Kenneth Dickstein and Gerstein, {Hertzel C.} and Peter Johnston and K{\o}ber, {Lars V.} and Francesca Lawson and Lewis, {Eldrin F.} and Maggioni, {Aldo P.} and McMurray, {John J V} and Lin Ping and Probstfield, {Jeffrey L.} and Solomon, {Scott D.} and Tardif, {Jean Claude} and Yujun Wu and Pfeffer, {Marc A.} and Ebrahim Barkoudah and Abdel Brahimi and David Charytan and Peter Finn and Aiden Flynn and Hartley, {L. Howard} and Galen Henderson and Jacob Joseph and Kayode Odutayo and Vinutha Rajesh and Ali Vazir and Larry Weinrauch and {Del Prato}, Stefano and John Petrie and Allen Kaplan and Phil Lieberman and Zuraw, {Bruce L.} and Eileen O'Reilly and Keyur Patel and Peter Allen and Aldo Scarpa and Mark Schattner and Christopher Granger and Jean Rouleau and David DeMets and Nishi Chaturvedi and Denis Raccah and Diego Aizenberg and Carlos Alvarez and Andres Alvarisqueta and Claudia Baccaro and Ines Bartolacci and Anselmo Bordonava and {Bustamante Labarta}, Miguel and Alberto Caccavo and Pedro Calella and Maria Cantero and Renzo Codutti and Victor Commendatore and Osvaldo Costamagna and Jose Cuello and Alberto Fernandez and {Garcia Duran}, Ruben and {Gomez Vilamajo}, Oscar and {Gorban De Lapertosa}, Silvia and Diego Grinfeld and Sonia Hermida and Mariana Lagrutta and {Leon De La Fuente}, Ricardo and Alberto Licheri and Hector Luciardi and Ignacio Mackinnon and Laura Maffei and Javier Marino and Oscar Monta{\~n}a and Leonardo Novaretto and Silvia Orio and Andres Orlandini and Alejandra Oviedo and {P{\'e}rez Manghi}, Federico and Cristian Patocchi and Hugo Ramos and Florencia Rolandi and {Saa Zarandon}, Raquel and Saavedra, {Silvia Salome} and Lilia Schiavi and Pablo Schygiel and Marcelo Trivi and Maria Ulla and Pedro Urdiales and Julio Vallejos and Marisa Vico and Florencia Waisman and John Amerena and Vincent Paul and Kunwarjit Sangla and {Van Gaal}, William and Bu Yeap and Peter Fasching and Thomas Pieber and Larisa Danilova and Natalya Mitkovskaya and Svetlana Sudzhaeva and Chantal Mathieu and Pouleur, {Anne Catherine} and Botelho, {Roberto Vieira} and Cerqueira, {Maria Jose} and Antonio Chacra and {Dos Santos}, Fabio and Gilson Feitosa and Adriana Forti and Milton Golbert and Alfredo Halpern and Miguel Hissa and Hugo Lisboa and Joao Moraes and Max Nery and Alexandre Quadros and Roberto Raduan and Gilmar Reis and {Ribeiro Filho}, Fernando and Guilherme Rollin and Paulo Rossi and Elizabete Santos and Jose Sgarbi and Juliana Souza and Souza, {Maria Regina} and Alexy Delchev and Valentin Ivanov and Neli Klyuchkova and Michael Kyoleyan and Georgi Levterov and Mariya Lucheva and Dimitar Raev and Rositsa Shumkova and Mariya Tokmakova and Maria Tzekova and Viktor Yordanov and Gordon Bailey and Olivier Bertrand and Rakesh Bhargava and Jeffrey Burton and Jean Campeau and Richard Dumas and Pierre Filteau and Gurcharan Syan and Rajinder Syan and George Tsoukas and Warnica, {James Wayne} and Silvia Acu{\~n}a and Guillermo Araneda and Lia Bunster and Leonardo Cobos and Ram{\'o}n Corbal{\'a}n and Gaston Dussaillant and German Eggers and Fernando Florenzano and Gonzalo Godoy and Huidobro, {Laura Andrea} and Rodolfo Lahsen and Fernando Lanas and Gladys Larenas and Leopoldo Manriquez and Marcelo Medina and Palma, {Juan Carlos} and Luis Perez and Sergio Potthoff and Carlos Raffo and Eliana Reyes and Victor Saavedra and Patricio Sanhueza and Pablo Sepulveda and Solis, {Carmen Lia} and Nestor Soto and Claudia Torres and Bernhard Westerberg and Mario Ya{\~n}ez and Li Chen and Yugang Dong and Jianling Du and Xiaohui Guo and Ping Han and Taohong Hu and Bin Jiang and Yuannan Ke and Zhanquan Li and Juming Lu and Changsheng Ma and Yongde Peng and Yongquan Shi and Guohai Su and Baopeng Tang and Biao Xu and Jiefu Yang and Jinkui Yang and Yanmin Yang and Accini, {Jose Luis} and Arteaga, {Juan Manuel} and Rodrigo Botero and Gilberto Castillo and Julian Coronel and Carlos Cure and Henry Garcia and Luis Garcia and Claudia Gomez and {Hernandez Triana}, Eric and Hector Hernandez and Monica Lopez and Patricio Lopez and Fernando Manzur and Dora Molina and Jaime Rodriguez and {Sanchez Vallejo}, Gregorio and Hernan Yupanqui and Jens Bronnum-Schou and {Kaiser Nielsen}, Peter and Henrik Nielsen and Henning R{\o}nne and Soeren Rasmussen and J{\o}rgen Rungby and Knud Skagen and Thomsen, {Kristian Korsgaard} and Christian Torp-Pedersen and Yan Duarte-Vera and {Marmol Alvear}, Ricardo and Carlos Pe{\~n}aherrera-Pati{\~n}o and Samir Assaad and Salah Shelbaya and Anu Ambos and Ulle Jakovlev and Maire Lubi and Kaja M{\"a}rtsin and Svea Rosenthal and Hella Vides and Juha Alanko and Pirkko Korsoff and Koski, {Anna Mari} and Jorma Lahtela and Lassi Nelimarkka and Jaakko Tuomilehto and Bertrand Cariou and Bogdan Catargi and Roxane Ducloux and Samy Hadjadj and Veronique Kerlan and Malecot, {Jean Marc} and Catherine Petit and Michel Rodier and Vakhtang Chumburidze and Salome Glonti and Zaza Lominadze and Fridon Todua and Christel Contzen and Cornelia Marck and Hermann Fischer and Andreas Hagenow and Agnes Himpel-B{\"o}nninghoff and Lars Kihm and Holger Killat and Klaus Kleinertz and Christine Kosch and Kristin Kreutzmann and Mariola Lappo and Bernardo Mertes and Richard Piechatzek and Martin Prohaska and Andrea Rinke and Detlev Schellenberg and Nicole Toursarkissian and Juan Arango and Ronaldo Gonzalez and Arnoldo Granados and Milton Herrera and Pablo Montenegro and Ricardo Munoz and Edgar Rodriguez and Erick Turcios and Renato Villalobos and Fernando Wyss and Sanjay Hatterjee and Manoj Chopda and Vijay Chopra and Neeta Deshpande and R. Dutta and Sudhanshu Dwivedi and Pramod Gandhi and Gupta, {Sandeep Kumar} and Gupta, {Jugal Bihari} and Sunil Gupta and Narendra Hiregouder and Sujeet Jha and Abhijeet Joshi and Noor Khan and Mukund Kumbla and Mohan Magdum and Keshava Murthy and Mukhya Prabhu and Rakesh Sahay and Selvamani Sethuraman and Navneet Shah and Paramesh Shamanna and Singh, {K. Singh} and Paminder Singh and Arun Somasekharan and Lakshminarayanappa Sreenivasamurthy and Pravin Supe and Faiad Adawi and Shaul Atar and Ohad Cohen and Shai Efrati and Eddy Karnieli and Eliezer Klainman and Oscar Minuchin and Ofri Mosenzon and Naftali Stern and Yoav Turgeman and Julio Wainstein and Gianluca Aimaretti and Cesare Berra and Ciardullo, {Anna Vittoria} and Agostino Consoli and Domenico Cucinotta and {Di Marco}, Sandra and Carlo Giorda and Carla Giordano and Edoardo Mannucci and Emanuela Orsi and Piermarco Piatti and Antonio Pontiroli and Paola Ponzani and Paolo Pozzilli and Angela Rivellese and Hiroshi Akahori and Yutaka Eki and Kenshi Fujii and Yoshiki Hata and Hideo Himeno and Atsushi Hirayama and Ichiro Kishimoto and Youichi Kobayashi and Hiroaki Miyaoka and Tetsuji Niiya and Yutaro Nishi and Akira Nozaki and Tatsuya Nunohiro and Tomiyoshi Saito and Yasuhiro Satoh and Akihiko Takahashi and Junichiro Takahashi and Hiroyuki Takase and Shinichi Takase and Yusuke Tsuboko and Mitsuru Tsujimoto and Motoyoshi Tsujino and Masahiro Tsuzuki and Shuichi Watanabe and Takahisa Yamada and Chung, {Wook Jin} and Sejoong Rim and Hakchul Jang and Ung Kim and Chung, {Choon Hee} and Shin, {Sung Hee} and Kyehun Kim and Jaetaek Kim and Seungwoon Rha and Lee, {Nae Hee} and Kim, {Chong Jin} and Park, {Kyong Soo} and Ildze Amolina and Kristine Ducena and Renate Helda and Ilze Konrade and Valdis Pirags and Iveta Sime and Jelena Sokolova and Vaida Kakariekiene and Roma Kavaliauskiene and Zaneta Petrulioniene and Gintare Sakalyte and Audrone Urboniene and Rima Zarankiene and Marittza Uribe and Pedro Garcia-Hernandez and Jose Garza and Abraham Vazquez-Garcia and Gonzalez, {Jose Gerardo} and Miguel Escalante and Alejandro Zavala and Edmundo Bayram and Jesus Hernandez-Mu{\~n}uzuri and Ramos and Lopez, {Gabriel Arturo} and Jesus Lujan and Martin Garcia-Soria and Raul Velasco-Sanchez and Ignacio Rodriguez and Silvia Jimenez and Cielmar Galeana and Eduardo Reyes and Susano Lara and Armando Garcia-Castillo and Castro, {Maria Guadalupe} and Raul Aguilar-Orozco and {Lopez Rosas}, Enrique and Maricela Vidrio and Guillermo Llamas and {Stobschinski De Alba}, {Carlos Alejandro} and Jaime Carranza-Madrigal and Francisco Cardosa-Torres and Cornel, {Jan Hein} and Paulus Dekkers and J. Frederiks and Wrm Hermans and Dirk Lok and Joan Meeder and Peter Nierop and John Cooper and Lappeg{\aa}rd, {Knut Tore} and Nedreb{\o}, {Bj{\o}rn Gunnar} and Eholo Castro and {Gonzalez Castillo}, Baldomero and Elis Gonzalez and {Nieto Ortega}, Ruben and Miguel Andrade and Jorge Calderon and Carlos Chavez and {Correa Flores}, {Roger Martin} and Julio Farfan and Libia Lu and Edith Luque and Helard Manrique and Walter Mogrovejo and Marcos Pariona-Javier and Miguel Pinto and Yudy Roldan and Carlos Zubiate and Antonio Dans and Gomez, {Maria Honolina} and Araceli Panelo and Nannette Rey and Sulit, {Dennis Jose} and Sy, {Rosa Allyn} and Miriam Timonera and Janusz Bednarski and Renata Bijata-Bronisz and Leszek Bryniarski and Benita Busz-Papiez and Eugenia Czajkowska-Kaczmarek and Anna Drzewiecka and Elzbieta Dulak and Maria Gorska and Maciej Hamankiewicz and Krzysztof Janik and Krzysztof Kincel and Marek Konieczny and Andrzej Lubinski and Magdalena Olszanecka-Glinianowicz and Piotr Ponikowski and Grazyna Pulka and Jerzy Rekosz and Dariusz Skudlarski and Katarzyna Szymkowiak and Przemyslaw Wilczewski and Nuno Bragan{\cc}a and Jo{\~a}o Duarte and Pedro Monteiro and Elisabete Rodrigues and Margarida Vinhas and Adina, {Pop Moldovan} and Avram, {Rodica Ioana} and Adriana Cif and Gabriela Creteanu and Dinu Dragomir and Ferariu, {Ioana Emilia} and Iancu, {Adrian Corneliu} and Octavian Istratoaie and Gabriel Ivanica and Radu Lichiardopol and Constantin Militaru and Bogdan Minescu and Adriana Onaca and Ella Pintilei and Cristian Podoleanu and Lavinia Pop and Bogdan Popa and Ranetti, {Aurelian Emil} and Doina Rosu and Adrian Tase and Tesloianu, {Dan Nicolae} and Dragos Vinereanu and Fail Ageev and Nadir Akhmedzhanov and Olga Barbarash and Vladimir Barbarich and Yury Belousov and Svetlana Berns and Igor Bokarev and Olga Bolshakova and Mikhail Boyarkin and Galina Chumakova and Platonov Dmitry and Sergey Fitilev and Albert Galyavich and Maria Glezer and Luidmila Ivanova and Victor Kalashnikov and Marina Kalashnikova and Yuri Karpov and Larisa Khaisheva and Yuri Khalimov and Zhanna Kobalava and Elena Kosmachova and Victor Kostenko and Natalya Koziolova and Elena Kulibaba and Victor Lesnov and Igor Libov and Nadezhda Lyamina and Valentin Markov and Valentin Moiseev and Olga Molchanova and Valentin Oleynikov and Olga Orlikova and Alexey Panov and Vladimir Rafalskiy and Tatiana Rodionova and Vasily Samitin and Vladimir Schokotov and Nataliya Shilkina and Zaur Shogenov and Sergey Shustov and Yuri Shvarts and Konstantin Sobolev and Raisa Stryuk and Ludmila Suplotova and Inna Viktorova and Alexander Vishnevsky and Natalia Vorokhobina and Vladimir Yakusevich and Sergey Yakushin and Vladimir Zadionchenko and Alsu Zalevskaya and Grigory Zalevsky and Anna Zateyshchikova and {Andjelic Jelic}, Marina and Radivoj Kocic and Snezana Komnenovic and Katarina Lalic and Nebojsa Lalic and Dragan Micic and Petar Otasevic and Milica Pesic and Petar Seferovic and Goran Stankovic and Susan Arnold and Lesley Burgess and Kathleen Coetzee and Saleem Dawood and Eluned Delport and I. Ebrahim and Graham Ellis and Siddique Ismail and Dudley Kelbe and Visvakuren Naidoo and Mpiko Ntsekhe and Sebastian, {Peter John} and Mirna Siebert and {Van Zyl}, Louis and Tjaart Venter and Elena Lonso and Isabel Antorrena and Vicent Bodi and Marta Botella and {De La Fuente}, Javier and Elias Delgado and {Duran Garcia}, Santiago and Jose Elorza and Fidel Enciso and Sonia Gaztambide and Francisco Marin and Victoria Martin and Didac Mauricio and Alfonso Soto and Manuel Vida and Gunnar Boberg and Gun J{\"o}rneskog and Johan Jendle and Ulrik Mathiesen and Svensson, {Karl Axel} and Ingemar Torstensson and Peter Vasko and Tiziano Moccetti and Chiang, {Chern En} and Chiu, {Yu Wei} and Huang, {Tsuei Yuan} and Lu, {Chieh Hsiang} and Dee Pei and Shyu, {Kou Gi} and Ueng, {Kwo Chang} and Wang, {Tzung Dau} and Mohamed Abid and {Ben Abdallah}, Nejib and Habib Haouala and Hedia Slimane and Borni Zidi and {Bascil Tutuncu}, Neslihan and Ahmet Camsari and Tuncay Delibasi and Nevin Dinccag and Hakan Kultursay and Ali Oto and Mahmut Sahin and Fusun Saygili and Zerrin Yigit and Cafer Zorkun and Oleksandr Karpenko and Vadym Korpachev and Olena Koval and Vitaliy Maslyanko and Mykhaylo Perepelytsya and Tetyana Pertseva and Olena Petrosyan and Leonid Rudenko and Oleg Sychov and Volodymyr Synenko and Vira Tseluyko and Larisa Zhuravleva and {Al Mahmeed}, Wael and Kaddaha, {Ghaida Mohamad} and Robert Andrews and Stephen Bain and Ambar Basu and Deepak Bhatnagar and Alex Bickerton and Duncan Browne and Martin Gibson and Peter Hammond and Fahmy Hanna and Basil Issa and Alan Jaap and Franklin Joseph and Edward Jude and Chris Kelly and Atir Khan and Rayaz Malik and Babu Mukhopadhyay and M. O'Kane and Gerry Rayman and Anthony Robinson and Desmond Rooney and Chris Sainsbury and Ponnusamy Saravanan and Jayadave Shakher and Baldev Singh and Jeremy Turner and Donald Whitelaw and John Wilding and Philip Wiles and Babafemi Adenuga and Zia Ahmad and Olakunle Akinboboye and Laura Akright and Paul Alappat and Mohamad Alawad and Teresa Alfonso and Ramin Alimard and Opada Alzohaili and Mehrdad Ariani and Chander Arora and Nasrin Azad and Samir Azzam and Sabrina Benjamin and Bradley Block and Eliza Borzadek and Warren Breisblatt and Tamis Bright and Leroy Byrd and Choyen Chiou and Ronald Chochinov and Tom Christensen and Elena Christofides and Robert Cohen and Gamil Dawood and {De Souza}, Jose and Michael Dempsey and Donald Eagerton and Cara East and Charles Elder and Ronald Fernando and Leon Fogelfeld and Jean Foucauld and William French and Mary Frohnauer and Mary Gaffney and Subroto Gangopadhyay and Harinder Gogia and Aidar Gosmanov and Craig Greenberg and Frank Greenway and Edward Hanna and Joe Hargrove and Anthony Harris and Bill Harris and Terence Hart and David Herrington and Mitzie Hewitt and David Howard and Kenneth Izuora and Preetham Jetty and Anoop Kapoor and Kasper, {Joseph F.} and Shaun Kelehan and Richard Kelly and Dean Kereiakes and Ajit Khaira and Misal Khan and Salman Khan and Elie Korban and Mikhail Kosiborod and Jacques Laguerre and James Larocque and Kashif Latif and Frank Lester and Philip Levin and Steven Levine and Charles Li and Charles Lovell and Steven Lupovitch and Madu, {Ivy Joan} and Vahid Mahabadi and Asif Mahmood and Stavros Maragos and Cary Mariash and Paul Martin and James Mathew and John Mathew and Michael May and Ronald Mayfield and Anthony McCall and Clayton Mcdaniel and Frank Mcgrew and Marcus Mckenzie and Ivan Mefford and Arvind Mehta and Ghiath Mikdadi and Magdy Mikhail and Travis Monchamp and Charles Moore and Michael Moran and Nidal Morrar and Jonathan Mosley and Mim Mulford and John Murray and Samer Nakhle and Mani Nallasivan and Alberto Odio and Charles Oh and Sarah Olelewe and Bryce Palchick and Yogesh Paliwal and Vasilios Papademetriou and Naresh Parikh and Sudhirkumar Patel and Lawrence Phillips and Thomas Pitts and Francisco Prieto and Rachel Puttnam and Arshed Quyyumi and Preet Randhawa and Marc Rendell and Francis Rhie and James Roberts and Jerome Robinson and Michael Robinson and John Rubino and Eugene Ryan and Steven Saathoff and Isaac Sachmechi and Ali Saifi and Abraham Salacata and Robyn Sanders and Jodi Sanson and Virginia Savin and Alex Schabauer and John Schmedtje and Alan Schwartz and Cranford Scott and Munni Selagamsetty and Michael Shannon and Sylvia Shaw and Dinesh Singal and Robert Sjoberg and Kenneth Smith and Carl Sofley and Anthony Sonn and Suzanne Sorof and Eugene Soroka and Spellman, {C. W.} and Jeffrey Steinhoff and Damodhar Suresh and Mohammad Tahir and Robert Tanenberg and Hemant Thawani and Stephen Thomson and James Thrasher and David Trachtenbarg and Michael Trotta and Weiming Tuan and Marcel Twahirwa and Guillermo Umpierrez and Brij Vaid and Carl Vance and Thomas Wang and Alberta Warner and Henry Watson and Sandra Weber and Brian Webster and Kathleen Weindorff and Michelle Welch and James Welker and Anthony White and Lindsey White and Marcus Williams and Wu, {Wen Chih} and Alan Wynne and Mark Yocono and Kevin Yuen",
year = "2015",
month = "5",
day = "1",
doi = "10.1016/j.ahj.2015.02.002",
language = "English",
volume = "169",
pages = "631--638.e7",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo

AU - Bentley-Lewis, Rhonda

AU - Aguilar, David

AU - Riddle, Matthew C.

AU - Claggett, Brian

AU - Diaz, Rafael

AU - Dickstein, Kenneth

AU - Gerstein, Hertzel C.

AU - Johnston, Peter

AU - Køber, Lars V.

AU - Lawson, Francesca

AU - Lewis, Eldrin F.

AU - Maggioni, Aldo P.

AU - McMurray, John J V

AU - Ping, Lin

AU - Probstfield, Jeffrey L.

AU - Solomon, Scott D.

AU - Tardif, Jean Claude

AU - Wu, Yujun

AU - Pfeffer, Marc A.

AU - Barkoudah, Ebrahim

AU - Brahimi, Abdel

AU - Charytan, David

AU - Finn, Peter

AU - Flynn, Aiden

AU - Hartley, L. Howard

AU - Henderson, Galen

AU - Joseph, Jacob

AU - Odutayo, Kayode

AU - Rajesh, Vinutha

AU - Vazir, Ali

AU - Weinrauch, Larry

AU - Del Prato, Stefano

AU - Petrie, John

AU - Kaplan, Allen

AU - Lieberman, Phil

AU - Zuraw, Bruce L.

AU - O'Reilly, Eileen

AU - Patel, Keyur

AU - Allen, Peter

AU - Scarpa, Aldo

AU - Schattner, Mark

AU - Granger, Christopher

AU - Rouleau, Jean

AU - DeMets, David

AU - Chaturvedi, Nishi

AU - Raccah, Denis

AU - Aizenberg, Diego

AU - Alvarez, Carlos

AU - Alvarisqueta, Andres

AU - Baccaro, Claudia

AU - Bartolacci, Ines

AU - Bordonava, Anselmo

AU - Bustamante Labarta, Miguel

AU - Caccavo, Alberto

AU - Calella, Pedro

AU - Cantero, Maria

AU - Codutti, Renzo

AU - Commendatore, Victor

AU - Costamagna, Osvaldo

AU - Cuello, Jose

AU - Fernandez, Alberto

AU - Garcia Duran, Ruben

AU - Gomez Vilamajo, Oscar

AU - Gorban De Lapertosa, Silvia

AU - Grinfeld, Diego

AU - Hermida, Sonia

AU - Lagrutta, Mariana

AU - Leon De La Fuente, Ricardo

AU - Licheri, Alberto

AU - Luciardi, Hector

AU - Mackinnon, Ignacio

AU - Maffei, Laura

AU - Marino, Javier

AU - Montaña, Oscar

AU - Novaretto, Leonardo

AU - Orio, Silvia

AU - Orlandini, Andres

AU - Oviedo, Alejandra

AU - Pérez Manghi, Federico

AU - Patocchi, Cristian

AU - Ramos, Hugo

AU - Rolandi, Florencia

AU - Saa Zarandon, Raquel

AU - Saavedra, Silvia Salome

AU - Schiavi, Lilia

AU - Schygiel, Pablo

AU - Trivi, Marcelo

AU - Ulla, Maria

AU - Urdiales, Pedro

AU - Vallejos, Julio

AU - Vico, Marisa

AU - Waisman, Florencia

AU - Amerena, John

AU - Paul, Vincent

AU - Sangla, Kunwarjit

AU - Van Gaal, William

AU - Yeap, Bu

AU - Fasching, Peter

AU - Pieber, Thomas

AU - Danilova, Larisa

AU - Mitkovskaya, Natalya

AU - Sudzhaeva, Svetlana

AU - Mathieu, Chantal

AU - Pouleur, Anne Catherine

AU - Botelho, Roberto Vieira

AU - Cerqueira, Maria Jose

AU - Chacra, Antonio

AU - Dos Santos, Fabio

AU - Feitosa, Gilson

AU - Forti, Adriana

AU - Golbert, Milton

AU - Halpern, Alfredo

AU - Hissa, Miguel

AU - Lisboa, Hugo

AU - Moraes, Joao

AU - Nery, Max

AU - Quadros, Alexandre

AU - Raduan, Roberto

AU - Reis, Gilmar

AU - Ribeiro Filho, Fernando

AU - Rollin, Guilherme

AU - Rossi, Paulo

AU - Santos, Elizabete

AU - Sgarbi, Jose

AU - Souza, Juliana

AU - Souza, Maria Regina

AU - Delchev, Alexy

AU - Ivanov, Valentin

AU - Klyuchkova, Neli

AU - Kyoleyan, Michael

AU - Levterov, Georgi

AU - Lucheva, Mariya

AU - Raev, Dimitar

AU - Shumkova, Rositsa

AU - Tokmakova, Mariya

AU - Tzekova, Maria

AU - Yordanov, Viktor

AU - Bailey, Gordon

AU - Bertrand, Olivier

AU - Bhargava, Rakesh

AU - Burton, Jeffrey

AU - Campeau, Jean

AU - Dumas, Richard

AU - Filteau, Pierre

AU - Syan, Gurcharan

AU - Syan, Rajinder

AU - Tsoukas, George

AU - Warnica, James Wayne

AU - Acuña, Silvia

AU - Araneda, Guillermo

AU - Bunster, Lia

AU - Cobos, Leonardo

AU - Corbalán, Ramón

AU - Dussaillant, Gaston

AU - Eggers, German

AU - Florenzano, Fernando

AU - Godoy, Gonzalo

AU - Huidobro, Laura Andrea

AU - Lahsen, Rodolfo

AU - Lanas, Fernando

AU - Larenas, Gladys

AU - Manriquez, Leopoldo

AU - Medina, Marcelo

AU - Palma, Juan Carlos

AU - Perez, Luis

AU - Potthoff, Sergio

AU - Raffo, Carlos

AU - Reyes, Eliana

AU - Saavedra, Victor

AU - Sanhueza, Patricio

AU - Sepulveda, Pablo

AU - Solis, Carmen Lia

AU - Soto, Nestor

AU - Torres, Claudia

AU - Westerberg, Bernhard

AU - Yañez, Mario

AU - Chen, Li

AU - Dong, Yugang

AU - Du, Jianling

AU - Guo, Xiaohui

AU - Han, Ping

AU - Hu, Taohong

AU - Jiang, Bin

AU - Ke, Yuannan

AU - Li, Zhanquan

AU - Lu, Juming

AU - Ma, Changsheng

AU - Peng, Yongde

AU - Shi, Yongquan

AU - Su, Guohai

AU - Tang, Baopeng

AU - Xu, Biao

AU - Yang, Jiefu

AU - Yang, Jinkui

AU - Yang, Yanmin

AU - Accini, Jose Luis

AU - Arteaga, Juan Manuel

AU - Botero, Rodrigo

AU - Castillo, Gilberto

AU - Coronel, Julian

AU - Cure, Carlos

AU - Garcia, Henry

AU - Garcia, Luis

AU - Gomez, Claudia

AU - Hernandez Triana, Eric

AU - Hernandez, Hector

AU - Lopez, Monica

AU - Lopez, Patricio

AU - Manzur, Fernando

AU - Molina, Dora

AU - Rodriguez, Jaime

AU - Sanchez Vallejo, Gregorio

AU - Yupanqui, Hernan

AU - Bronnum-Schou, Jens

AU - Kaiser Nielsen, Peter

AU - Nielsen, Henrik

AU - Rønne, Henning

AU - Rasmussen, Soeren

AU - Rungby, Jørgen

AU - Skagen, Knud

AU - Thomsen, Kristian Korsgaard

AU - Torp-Pedersen, Christian

AU - Duarte-Vera, Yan

AU - Marmol Alvear, Ricardo

AU - Peñaherrera-Patiño, Carlos

AU - Assaad, Samir

AU - Shelbaya, Salah

AU - Ambos, Anu

AU - Jakovlev, Ulle

AU - Lubi, Maire

AU - Märtsin, Kaja

AU - Rosenthal, Svea

AU - Vides, Hella

AU - Alanko, Juha

AU - Korsoff, Pirkko

AU - Koski, Anna Mari

AU - Lahtela, Jorma

AU - Nelimarkka, Lassi

AU - Tuomilehto, Jaakko

AU - Cariou, Bertrand

AU - Catargi, Bogdan

AU - Ducloux, Roxane

AU - Hadjadj, Samy

AU - Kerlan, Veronique

AU - Malecot, Jean Marc

AU - Petit, Catherine

AU - Rodier, Michel

AU - Chumburidze, Vakhtang

AU - Glonti, Salome

AU - Lominadze, Zaza

AU - Todua, Fridon

AU - Contzen, Christel

AU - Marck, Cornelia

AU - Fischer, Hermann

AU - Hagenow, Andreas

AU - Himpel-Bönninghoff, Agnes

AU - Kihm, Lars

AU - Killat, Holger

AU - Kleinertz, Klaus

AU - Kosch, Christine

AU - Kreutzmann, Kristin

AU - Lappo, Mariola

AU - Mertes, Bernardo

AU - Piechatzek, Richard

AU - Prohaska, Martin

AU - Rinke, Andrea

AU - Schellenberg, Detlev

AU - Toursarkissian, Nicole

AU - Arango, Juan

AU - Gonzalez, Ronaldo

AU - Granados, Arnoldo

AU - Herrera, Milton

AU - Montenegro, Pablo

AU - Munoz, Ricardo

AU - Rodriguez, Edgar

AU - Turcios, Erick

AU - Villalobos, Renato

AU - Wyss, Fernando

AU - Hatterjee, Sanjay

AU - Chopda, Manoj

AU - Chopra, Vijay

AU - Deshpande, Neeta

AU - Dutta, R.

AU - Dwivedi, Sudhanshu

AU - Gandhi, Pramod

AU - Gupta, Sandeep Kumar

AU - Gupta, Jugal Bihari

AU - Gupta, Sunil

AU - Hiregouder, Narendra

AU - Jha, Sujeet

AU - Joshi, Abhijeet

AU - Khan, Noor

AU - Kumbla, Mukund

AU - Magdum, Mohan

AU - Murthy, Keshava

AU - Prabhu, Mukhya

AU - Sahay, Rakesh

AU - Sethuraman, Selvamani

AU - Shah, Navneet

AU - Shamanna, Paramesh

AU - Singh, K. Singh

AU - Singh, Paminder

AU - Somasekharan, Arun

AU - Sreenivasamurthy, Lakshminarayanappa

AU - Supe, Pravin

AU - Adawi, Faiad

AU - Atar, Shaul

AU - Cohen, Ohad

AU - Efrati, Shai

AU - Karnieli, Eddy

AU - Klainman, Eliezer

AU - Minuchin, Oscar

AU - Mosenzon, Ofri

AU - Stern, Naftali

AU - Turgeman, Yoav

AU - Wainstein, Julio

AU - Aimaretti, Gianluca

AU - Berra, Cesare

AU - Ciardullo, Anna Vittoria

AU - Consoli, Agostino

AU - Cucinotta, Domenico

AU - Di Marco, Sandra

AU - Giorda, Carlo

AU - Giordano, Carla

AU - Mannucci, Edoardo

AU - Orsi, Emanuela

AU - Piatti, Piermarco

AU - Pontiroli, Antonio

AU - Ponzani, Paola

AU - Pozzilli, Paolo

AU - Rivellese, Angela

AU - Akahori, Hiroshi

AU - Eki, Yutaka

AU - Fujii, Kenshi

AU - Hata, Yoshiki

AU - Himeno, Hideo

AU - Hirayama, Atsushi

AU - Kishimoto, Ichiro

AU - Kobayashi, Youichi

AU - Miyaoka, Hiroaki

AU - Niiya, Tetsuji

AU - Nishi, Yutaro

AU - Nozaki, Akira

AU - Nunohiro, Tatsuya

AU - Saito, Tomiyoshi

AU - Satoh, Yasuhiro

AU - Takahashi, Akihiko

AU - Takahashi, Junichiro

AU - Takase, Hiroyuki

AU - Takase, Shinichi

AU - Tsuboko, Yusuke

AU - Tsujimoto, Mitsuru

AU - Tsujino, Motoyoshi

AU - Tsuzuki, Masahiro

AU - Watanabe, Shuichi

AU - Yamada, Takahisa

AU - Chung, Wook Jin

AU - Rim, Sejoong

AU - Jang, Hakchul

AU - Kim, Ung

AU - Chung, Choon Hee

AU - Shin, Sung Hee

AU - Kim, Kyehun

AU - Kim, Jaetaek

AU - Rha, Seungwoon

AU - Lee, Nae Hee

AU - Kim, Chong Jin

AU - Park, Kyong Soo

AU - Amolina, Ildze

AU - Ducena, Kristine

AU - Helda, Renate

AU - Konrade, Ilze

AU - Pirags, Valdis

AU - Sime, Iveta

AU - Sokolova, Jelena

AU - Kakariekiene, Vaida

AU - Kavaliauskiene, Roma

AU - Petrulioniene, Zaneta

AU - Sakalyte, Gintare

AU - Urboniene, Audrone

AU - Zarankiene, Rima

AU - Uribe, Marittza

AU - Garcia-Hernandez, Pedro

AU - Garza, Jose

AU - Vazquez-Garcia, Abraham

AU - Gonzalez, Jose Gerardo

AU - Escalante, Miguel

AU - Zavala, Alejandro

AU - Bayram, Edmundo

AU - Hernandez-Muñuzuri, Jesus

AU - Ramos,

AU - Lopez, Gabriel Arturo

AU - Lujan, Jesus

AU - Garcia-Soria, Martin

AU - Velasco-Sanchez, Raul

AU - Rodriguez, Ignacio

AU - Jimenez, Silvia

AU - Galeana, Cielmar

AU - Reyes, Eduardo

AU - Lara, Susano

AU - Garcia-Castillo, Armando

AU - Castro, Maria Guadalupe

AU - Aguilar-Orozco, Raul

AU - Lopez Rosas, Enrique

AU - Vidrio, Maricela

AU - Llamas, Guillermo

AU - Stobschinski De Alba, Carlos Alejandro

AU - Carranza-Madrigal, Jaime

AU - Cardosa-Torres, Francisco

AU - Cornel, Jan Hein

AU - Dekkers, Paulus

AU - Frederiks, J.

AU - Hermans, Wrm

AU - Lok, Dirk

AU - Meeder, Joan

AU - Nierop, Peter

AU - Cooper, John

AU - Lappegård, Knut Tore

AU - Nedrebø, Bjørn Gunnar

AU - Castro, Eholo

AU - Gonzalez Castillo, Baldomero

AU - Gonzalez, Elis

AU - Nieto Ortega, Ruben

AU - Andrade, Miguel

AU - Calderon, Jorge

AU - Chavez, Carlos

AU - Correa Flores, Roger Martin

AU - Farfan, Julio

AU - Lu, Libia

AU - Luque, Edith

AU - Manrique, Helard

AU - Mogrovejo, Walter

AU - Pariona-Javier, Marcos

AU - Pinto, Miguel

AU - Roldan, Yudy

AU - Zubiate, Carlos

AU - Dans, Antonio

AU - Gomez, Maria Honolina

AU - Panelo, Araceli

AU - Rey, Nannette

AU - Sulit, Dennis Jose

AU - Sy, Rosa Allyn

AU - Timonera, Miriam

AU - Bednarski, Janusz

AU - Bijata-Bronisz, Renata

AU - Bryniarski, Leszek

AU - Busz-Papiez, Benita

AU - Czajkowska-Kaczmarek, Eugenia

AU - Drzewiecka, Anna

AU - Dulak, Elzbieta

AU - Gorska, Maria

AU - Hamankiewicz, Maciej

AU - Janik, Krzysztof

AU - Kincel, Krzysztof

AU - Konieczny, Marek

AU - Lubinski, Andrzej

AU - Olszanecka-Glinianowicz, Magdalena

AU - Ponikowski, Piotr

AU - Pulka, Grazyna

AU - Rekosz, Jerzy

AU - Skudlarski, Dariusz

AU - Szymkowiak, Katarzyna

AU - Wilczewski, Przemyslaw

AU - Bragança, Nuno

AU - Duarte, João

AU - Monteiro, Pedro

AU - Rodrigues, Elisabete

AU - Vinhas, Margarida

AU - Adina, Pop Moldovan

AU - Avram, Rodica Ioana

AU - Cif, Adriana

AU - Creteanu, Gabriela

AU - Dragomir, Dinu

AU - Ferariu, Ioana Emilia

AU - Iancu, Adrian Corneliu

AU - Istratoaie, Octavian

AU - Ivanica, Gabriel

AU - Lichiardopol, Radu

AU - Militaru, Constantin

AU - Minescu, Bogdan

AU - Onaca, Adriana

AU - Pintilei, Ella

AU - Podoleanu, Cristian

AU - Pop, Lavinia

AU - Popa, Bogdan

AU - Ranetti, Aurelian Emil

AU - Rosu, Doina

AU - Tase, Adrian

AU - Tesloianu, Dan Nicolae

AU - Vinereanu, Dragos

AU - Ageev, Fail

AU - Akhmedzhanov, Nadir

AU - Barbarash, Olga

AU - Barbarich, Vladimir

AU - Belousov, Yury

AU - Berns, Svetlana

AU - Bokarev, Igor

AU - Bolshakova, Olga

AU - Boyarkin, Mikhail

AU - Chumakova, Galina

AU - Dmitry, Platonov

AU - Fitilev, Sergey

AU - Galyavich, Albert

AU - Glezer, Maria

AU - Ivanova, Luidmila

AU - Kalashnikov, Victor

AU - Kalashnikova, Marina

AU - Karpov, Yuri

AU - Khaisheva, Larisa

AU - Khalimov, Yuri

AU - Kobalava, Zhanna

AU - Kosmachova, Elena

AU - Kostenko, Victor

AU - Koziolova, Natalya

AU - Kulibaba, Elena

AU - Lesnov, Victor

AU - Libov, Igor

AU - Lyamina, Nadezhda

AU - Markov, Valentin

AU - Moiseev, Valentin

AU - Molchanova, Olga

AU - Oleynikov, Valentin

AU - Orlikova, Olga

AU - Panov, Alexey

AU - Rafalskiy, Vladimir

AU - Rodionova, Tatiana

AU - Samitin, Vasily

AU - Schokotov, Vladimir

AU - Shilkina, Nataliya

AU - Shogenov, Zaur

AU - Shustov, Sergey

AU - Shvarts, Yuri

AU - Sobolev, Konstantin

AU - Stryuk, Raisa

AU - Suplotova, Ludmila

AU - Viktorova, Inna

AU - Vishnevsky, Alexander

AU - Vorokhobina, Natalia

AU - Yakusevich, Vladimir

AU - Yakushin, Sergey

AU - Zadionchenko, Vladimir

AU - Zalevskaya, Alsu

AU - Zalevsky, Grigory

AU - Zateyshchikova, Anna

AU - Andjelic Jelic, Marina

AU - Kocic, Radivoj

AU - Komnenovic, Snezana

AU - Lalic, Katarina

AU - Lalic, Nebojsa

AU - Micic, Dragan

AU - Otasevic, Petar

AU - Pesic, Milica

AU - Seferovic, Petar

AU - Stankovic, Goran

AU - Arnold, Susan

AU - Burgess, Lesley

AU - Coetzee, Kathleen

AU - Dawood, Saleem

AU - Delport, Eluned

AU - Ebrahim, I.

AU - Ellis, Graham

AU - Ismail, Siddique

AU - Kelbe, Dudley

AU - Naidoo, Visvakuren

AU - Ntsekhe, Mpiko

AU - Sebastian, Peter John

AU - Siebert, Mirna

AU - Van Zyl, Louis

AU - Venter, Tjaart

AU - Lonso, Elena

AU - Antorrena, Isabel

AU - Bodi, Vicent

AU - Botella, Marta

AU - De La Fuente, Javier

AU - Delgado, Elias

AU - Duran Garcia, Santiago

AU - Elorza, Jose

AU - Enciso, Fidel

AU - Gaztambide, Sonia

AU - Marin, Francisco

AU - Martin, Victoria

AU - Mauricio, Didac

AU - Soto, Alfonso

AU - Vida, Manuel

AU - Boberg, Gunnar

AU - Jörneskog, Gun

AU - Jendle, Johan

AU - Mathiesen, Ulrik

AU - Svensson, Karl Axel

AU - Torstensson, Ingemar

AU - Vasko, Peter

AU - Moccetti, Tiziano

AU - Chiang, Chern En

AU - Chiu, Yu Wei

AU - Huang, Tsuei Yuan

AU - Lu, Chieh Hsiang

AU - Pei, Dee

AU - Shyu, Kou Gi

AU - Ueng, Kwo Chang

AU - Wang, Tzung Dau

AU - Abid, Mohamed

AU - Ben Abdallah, Nejib

AU - Haouala, Habib

AU - Slimane, Hedia

AU - Zidi, Borni

AU - Bascil Tutuncu, Neslihan

AU - Camsari, Ahmet

AU - Delibasi, Tuncay

AU - Dinccag, Nevin

AU - Kultursay, Hakan

AU - Oto, Ali

AU - Sahin, Mahmut

AU - Saygili, Fusun

AU - Yigit, Zerrin

AU - Zorkun, Cafer

AU - Karpenko, Oleksandr

AU - Korpachev, Vadym

AU - Koval, Olena

AU - Maslyanko, Vitaliy

AU - Perepelytsya, Mykhaylo

AU - Pertseva, Tetyana

AU - Petrosyan, Olena

AU - Rudenko, Leonid

AU - Sychov, Oleg

AU - Synenko, Volodymyr

AU - Tseluyko, Vira

AU - Zhuravleva, Larisa

AU - Al Mahmeed, Wael

AU - Kaddaha, Ghaida Mohamad

AU - Andrews, Robert

AU - Bain, Stephen

AU - Basu, Ambar

AU - Bhatnagar, Deepak

AU - Bickerton, Alex

AU - Browne, Duncan

AU - Gibson, Martin

AU - Hammond, Peter

AU - Hanna, Fahmy

AU - Issa, Basil

AU - Jaap, Alan

AU - Joseph, Franklin

AU - Jude, Edward

AU - Kelly, Chris

AU - Khan, Atir

AU - Malik, Rayaz

AU - Mukhopadhyay, Babu

AU - O'Kane, M.

AU - Rayman, Gerry

AU - Robinson, Anthony

AU - Rooney, Desmond

AU - Sainsbury, Chris

AU - Saravanan, Ponnusamy

AU - Shakher, Jayadave

AU - Singh, Baldev

AU - Turner, Jeremy

AU - Whitelaw, Donald

AU - Wilding, John

AU - Wiles, Philip

AU - Adenuga, Babafemi

AU - Ahmad, Zia

AU - Akinboboye, Olakunle

AU - Akright, Laura

AU - Alappat, Paul

AU - Alawad, Mohamad

AU - Alfonso, Teresa

AU - Alimard, Ramin

AU - Alzohaili, Opada

AU - Ariani, Mehrdad

AU - Arora, Chander

AU - Azad, Nasrin

AU - Azzam, Samir

AU - Benjamin, Sabrina

AU - Block, Bradley

AU - Borzadek, Eliza

AU - Breisblatt, Warren

AU - Bright, Tamis

AU - Byrd, Leroy

AU - Chiou, Choyen

AU - Chochinov, Ronald

AU - Christensen, Tom

AU - Christofides, Elena

AU - Cohen, Robert

AU - Dawood, Gamil

AU - De Souza, Jose

AU - Dempsey, Michael

AU - Eagerton, Donald

AU - East, Cara

AU - Elder, Charles

AU - Fernando, Ronald

AU - Fogelfeld, Leon

AU - Foucauld, Jean

AU - French, William

AU - Frohnauer, Mary

AU - Gaffney, Mary

AU - Gangopadhyay, Subroto

AU - Gogia, Harinder

AU - Gosmanov, Aidar

AU - Greenberg, Craig

AU - Greenway, Frank

AU - Hanna, Edward

AU - Hargrove, Joe

AU - Harris, Anthony

AU - Harris, Bill

AU - Hart, Terence

AU - Herrington, David

AU - Hewitt, Mitzie

AU - Howard, David

AU - Izuora, Kenneth

AU - Jetty, Preetham

AU - Kapoor, Anoop

AU - Kasper, Joseph F.

AU - Kelehan, Shaun

AU - Kelly, Richard

AU - Kereiakes, Dean

AU - Khaira, Ajit

AU - Khan, Misal

AU - Khan, Salman

AU - Korban, Elie

AU - Kosiborod, Mikhail

AU - Laguerre, Jacques

AU - Larocque, James

AU - Latif, Kashif

AU - Lester, Frank

AU - Levin, Philip

AU - Levine, Steven

AU - Li, Charles

AU - Lovell, Charles

AU - Lupovitch, Steven

AU - Madu, Ivy Joan

AU - Mahabadi, Vahid

AU - Mahmood, Asif

AU - Maragos, Stavros

AU - Mariash, Cary

AU - Martin, Paul

AU - Mathew, James

AU - Mathew, John

AU - May, Michael

AU - Mayfield, Ronald

AU - McCall, Anthony

AU - Mcdaniel, Clayton

AU - Mcgrew, Frank

AU - Mckenzie, Marcus

AU - Mefford, Ivan

AU - Mehta, Arvind

AU - Mikdadi, Ghiath

AU - Mikhail, Magdy

AU - Monchamp, Travis

AU - Moore, Charles

AU - Moran, Michael

AU - Morrar, Nidal

AU - Mosley, Jonathan

AU - Mulford, Mim

AU - Murray, John

AU - Nakhle, Samer

AU - Nallasivan, Mani

AU - Odio, Alberto

AU - Oh, Charles

AU - Olelewe, Sarah

AU - Palchick, Bryce

AU - Paliwal, Yogesh

AU - Papademetriou, Vasilios

AU - Parikh, Naresh

AU - Patel, Sudhirkumar

AU - Phillips, Lawrence

AU - Pitts, Thomas

AU - Prieto, Francisco

AU - Puttnam, Rachel

AU - Quyyumi, Arshed

AU - Randhawa, Preet

AU - Rendell, Marc

AU - Rhie, Francis

AU - Roberts, James

AU - Robinson, Jerome

AU - Robinson, Michael

AU - Rubino, John

AU - Ryan, Eugene

AU - Saathoff, Steven

AU - Sachmechi, Isaac

AU - Saifi, Ali

AU - Salacata, Abraham

AU - Sanders, Robyn

AU - Sanson, Jodi

AU - Savin, Virginia

AU - Schabauer, Alex

AU - Schmedtje, John

AU - Schwartz, Alan

AU - Scott, Cranford

AU - Selagamsetty, Munni

AU - Shannon, Michael

AU - Shaw, Sylvia

AU - Singal, Dinesh

AU - Sjoberg, Robert

AU - Smith, Kenneth

AU - Sofley, Carl

AU - Sonn, Anthony

AU - Sorof, Suzanne

AU - Soroka, Eugene

AU - Spellman, C. W.

AU - Steinhoff, Jeffrey

AU - Suresh, Damodhar

AU - Tahir, Mohammad

AU - Tanenberg, Robert

AU - Thawani, Hemant

AU - Thomson, Stephen

AU - Thrasher, James

AU - Trachtenbarg, David

AU - Trotta, Michael

AU - Tuan, Weiming

AU - Twahirwa, Marcel

AU - Umpierrez, Guillermo

AU - Vaid, Brij

AU - Vance, Carl

AU - Wang, Thomas

AU - Warner, Alberta

AU - Watson, Henry

AU - Weber, Sandra

AU - Webster, Brian

AU - Weindorff, Kathleen

AU - Welch, Michelle

AU - Welker, James

AU - White, Anthony

AU - White, Lindsey

AU - Williams, Marcus

AU - Wu, Wen Chih

AU - Wynne, Alan

AU - Yocono, Mark

AU - Yuen, Kevin

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Background: Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients with T2DM and acute coronary syndrome (ACS) have a particularly high risk of CV events. The glucagonlike peptide 1 receptor agonist, lixisenatide, improves glycemia, but its effects on CV events have not been thoroughly evaluated. Methods: ELIXA (www.clinicaltrials.gov no. NCT01147250) is a randomized, double-blind, placebo-controlled, parallelgroup, multicenter study of lixisenatide in patients with T2DM and a recent ACS event. The primary aim is to evaluate the effects of lixisenatide on CV morbidity and mortality in a population at high CV risk. The primary efficacy end point is a composite of time to CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. Data are systematically collected for safety outcomes, including hypoglycemia, pancreatitis, and malignancy. Results: Enrollment began in July 2010 and ended in August 2013; 6,068 patients from 49 countries were randomized. Of these, 69% are men and 75% are white; at baseline, the mean ± SD age was 60.3 ± 9.7 years, body mass index was 30.2 ± 5.7 kg/m2, and duration of T2DM was 9.3±8.2 years. The qualifying ACS wasamyocardial infarctionin83% and unstableangina in 17%. The study will continue until the positive adjudication of the protocol-specified number of primary CV events. Conclusion: ELIXA will be the first trial to report the safety and efficacy of a glucagon-like peptide 1 receptor agonist in people with T2DM and high CV event risk.

AB - Background: Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients with T2DM and acute coronary syndrome (ACS) have a particularly high risk of CV events. The glucagonlike peptide 1 receptor agonist, lixisenatide, improves glycemia, but its effects on CV events have not been thoroughly evaluated. Methods: ELIXA (www.clinicaltrials.gov no. NCT01147250) is a randomized, double-blind, placebo-controlled, parallelgroup, multicenter study of lixisenatide in patients with T2DM and a recent ACS event. The primary aim is to evaluate the effects of lixisenatide on CV morbidity and mortality in a population at high CV risk. The primary efficacy end point is a composite of time to CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. Data are systematically collected for safety outcomes, including hypoglycemia, pancreatitis, and malignancy. Results: Enrollment began in July 2010 and ended in August 2013; 6,068 patients from 49 countries were randomized. Of these, 69% are men and 75% are white; at baseline, the mean ± SD age was 60.3 ± 9.7 years, body mass index was 30.2 ± 5.7 kg/m2, and duration of T2DM was 9.3±8.2 years. The qualifying ACS wasamyocardial infarctionin83% and unstableangina in 17%. The study will continue until the positive adjudication of the protocol-specified number of primary CV events. Conclusion: ELIXA will be the first trial to report the safety and efficacy of a glucagon-like peptide 1 receptor agonist in people with T2DM and high CV event risk.

UR - http://www.scopus.com/inward/record.url?scp=84929289581&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929289581&partnerID=8YFLogxK

U2 - 10.1016/j.ahj.2015.02.002

DO - 10.1016/j.ahj.2015.02.002

M3 - Article

VL - 169

SP - 631-638.e7

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 5

ER -