Relapse in schizophrenia: Is there a relationship to substance abuse?

Sanjay Gupta, Shelton Hendricks, Anne M. Kenkel, Subhash C. Bhatia, Ernest A. Haffke

Research output: Contribution to journalArticlepeer-review

106 Scopus citations


This retrospective study evaluated relapse in 22 patients with schizophrenia, comparing substance abusers with nonabusers. Medication compliance was ensured as all subjects were treated with decanoate neuroleptics. Substance abuse was documented by multiple urine drug screens. Substance abusers had a significantly higher readmission rate to the hospital compared to nonabusers. These data suggest that in the presence of documented medication compliance substance abuse remains a major factor contributing towards relapse.

Original languageEnglish (US)
Pages (from-to)153-156
Number of pages4
JournalSchizophrenia Research
Issue number1-2
StatePublished - May 1996

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Biological Psychiatry


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