Retained Asymptomatic Third Molars and Risk for Second Molar Pathology

M. E. Nunn, M. D. Fish, R. I. Garcia, E. K. Kaye, R. Figueroa, A. Gohel, M. Ito, H. J. Lee, D. E. Williams, T. Miyamoto

Research output: Contribution to journalArticlepeer-review

84 Scopus citations


Prophylactic extraction of unerupted asymptomatic third molars is the most common oral surgery procedure in the United States. However, limited evidence exists to justify its costs and associated morbidity. We analyzed data collected over 25 years from 416 adult men enrolled in the Veterans Affairs Dental Longitudinal Study to evaluate the association of retained asymptomatic third molars with risk of adjacent second molar pathology (caries and/or periodontitis), based on third molar status (i.e., absent, erupted, or unerupted). Unerupted molars were further categorized as either "soft tissue" or "bony" impacted. We found that the lowest prevalence and incidence of second molar pathology occurred when the adjacent third molar was absent. The presence of a third molar that was soft tissue impacted increased the risk of incident second molar pathology 4.88-fold (95% confidence interval: 2.62, 9.08). Having an erupted or "bony" impacted third molar increased the risk of incident second molar pathology by 1.74 (95% confidence interval: 1.34, 2.25) and 2.16 (95% confidence interval: 1.56, 2.99), respectively. The retention of third molars is associated with increased risk of second molar pathology in middle-aged and older adult men.

Original languageEnglish (US)
Pages (from-to)1095-1099
Number of pages5
JournalJournal of dental research
Issue number12
StatePublished - Dec 2013

All Science Journal Classification (ASJC) codes

  • Dentistry(all)


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