Review of abdominoperineal resections for cancer

Robert Joseph Fitzgibbons, William W. Harkrider, Isidore Cohn

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

One hundred eighty-six consecutive abdominoperineal resections for primary carcinoma of the anus, rectum, or sigmoid colon performed at Charity Hospital of Louisiana at New Orleans between January 1, 1963 and December 31, 1974 were reviewed. The operative mortality was 16 per cent. Complications during the same hospitalization occurred in 70 per cent of the patients. Although most of the complications were minor, 22 per cent did require some form of surgical intervention. Twenty-nine per cent of the patients who were discharged developed late mechanical or cancer-caused complications which required surgical correction. A history of congestive heart failure or a significant weight loss were the most consistent preoperative findings in the operative mortality group. The overall five year survival rate was 25 per cent. White females with no history of weight loss had the best long-term prognosis. Better survival in white patients can be accounted for by the less advanced lesions in these patients. No such difference between male and female patients could be demonstrated. Better selection of surgical candidates with alternate forms of therapy for poor risk patients have probably been the most significant factors in decreasing the operative mortality from 21 per cent in the first six years of the study to 9 per cent in the last six years. Primary closure of the perineal wound would appear to be of value in decreasing operative morbidity.

Original languageEnglish
Pages (from-to)624-629
Number of pages6
JournalAmerican Journal of Surgery
Volume134
Issue number5
DOIs
StatePublished - 1977
Externally publishedYes

Fingerprint

Neoplasms
Mortality
Weight Loss
Charities
Anal Canal
Sigmoid Colon
Rectum
Hospitalization
Survival Rate
Heart Failure
Morbidity
Carcinoma
Survival
Wounds and Injuries
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Review of abdominoperineal resections for cancer. / Fitzgibbons, Robert Joseph; Harkrider, William W.; Cohn, Isidore.

In: American Journal of Surgery, Vol. 134, No. 5, 1977, p. 624-629.

Research output: Contribution to journalReview article

Fitzgibbons, Robert Joseph ; Harkrider, William W. ; Cohn, Isidore. / Review of abdominoperineal resections for cancer. In: American Journal of Surgery. 1977 ; Vol. 134, No. 5. pp. 624-629.
@article{7336c8d5f1be4c2684e918373fc75ebd,
title = "Review of abdominoperineal resections for cancer",
abstract = "One hundred eighty-six consecutive abdominoperineal resections for primary carcinoma of the anus, rectum, or sigmoid colon performed at Charity Hospital of Louisiana at New Orleans between January 1, 1963 and December 31, 1974 were reviewed. The operative mortality was 16 per cent. Complications during the same hospitalization occurred in 70 per cent of the patients. Although most of the complications were minor, 22 per cent did require some form of surgical intervention. Twenty-nine per cent of the patients who were discharged developed late mechanical or cancer-caused complications which required surgical correction. A history of congestive heart failure or a significant weight loss were the most consistent preoperative findings in the operative mortality group. The overall five year survival rate was 25 per cent. White females with no history of weight loss had the best long-term prognosis. Better survival in white patients can be accounted for by the less advanced lesions in these patients. No such difference between male and female patients could be demonstrated. Better selection of surgical candidates with alternate forms of therapy for poor risk patients have probably been the most significant factors in decreasing the operative mortality from 21 per cent in the first six years of the study to 9 per cent in the last six years. Primary closure of the perineal wound would appear to be of value in decreasing operative morbidity.",
author = "Fitzgibbons, {Robert Joseph} and Harkrider, {William W.} and Isidore Cohn",
year = "1977",
doi = "10.1016/0002-9610(77)90450-0",
language = "English",
volume = "134",
pages = "624--629",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Review of abdominoperineal resections for cancer

AU - Fitzgibbons, Robert Joseph

AU - Harkrider, William W.

AU - Cohn, Isidore

PY - 1977

Y1 - 1977

N2 - One hundred eighty-six consecutive abdominoperineal resections for primary carcinoma of the anus, rectum, or sigmoid colon performed at Charity Hospital of Louisiana at New Orleans between January 1, 1963 and December 31, 1974 were reviewed. The operative mortality was 16 per cent. Complications during the same hospitalization occurred in 70 per cent of the patients. Although most of the complications were minor, 22 per cent did require some form of surgical intervention. Twenty-nine per cent of the patients who were discharged developed late mechanical or cancer-caused complications which required surgical correction. A history of congestive heart failure or a significant weight loss were the most consistent preoperative findings in the operative mortality group. The overall five year survival rate was 25 per cent. White females with no history of weight loss had the best long-term prognosis. Better survival in white patients can be accounted for by the less advanced lesions in these patients. No such difference between male and female patients could be demonstrated. Better selection of surgical candidates with alternate forms of therapy for poor risk patients have probably been the most significant factors in decreasing the operative mortality from 21 per cent in the first six years of the study to 9 per cent in the last six years. Primary closure of the perineal wound would appear to be of value in decreasing operative morbidity.

AB - One hundred eighty-six consecutive abdominoperineal resections for primary carcinoma of the anus, rectum, or sigmoid colon performed at Charity Hospital of Louisiana at New Orleans between January 1, 1963 and December 31, 1974 were reviewed. The operative mortality was 16 per cent. Complications during the same hospitalization occurred in 70 per cent of the patients. Although most of the complications were minor, 22 per cent did require some form of surgical intervention. Twenty-nine per cent of the patients who were discharged developed late mechanical or cancer-caused complications which required surgical correction. A history of congestive heart failure or a significant weight loss were the most consistent preoperative findings in the operative mortality group. The overall five year survival rate was 25 per cent. White females with no history of weight loss had the best long-term prognosis. Better survival in white patients can be accounted for by the less advanced lesions in these patients. No such difference between male and female patients could be demonstrated. Better selection of surgical candidates with alternate forms of therapy for poor risk patients have probably been the most significant factors in decreasing the operative mortality from 21 per cent in the first six years of the study to 9 per cent in the last six years. Primary closure of the perineal wound would appear to be of value in decreasing operative morbidity.

UR - http://www.scopus.com/inward/record.url?scp=0017655670&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017655670&partnerID=8YFLogxK

U2 - 10.1016/0002-9610(77)90450-0

DO - 10.1016/0002-9610(77)90450-0

M3 - Review article

C2 - 920894

AN - SCOPUS:0017655670

VL - 134

SP - 624

EP - 629

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 5

ER -