Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations

J. Bradley Oldemeyer; Richard J. Lund; Matt Koch; A. John Meares; Robert Dunlay

doi:10.1159/000047304

Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations

J. Bradley Oldemeyer, Richard J. Lund, Matt Koch, A. John Meares, Robert Dunlay

School of Medicine

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Statin-fibrate combinations are commonly used to treat hyperlipidemia. These drugs have been previously reported to cause rhabdomyolysis with acute renal failure. Whether different statin-fibrate combinations have different risks for rhabdomyolysis is not known. We report a patient who developed rhabdomyolysis with acute renal failure pomptly after switching from the combination of pravastatin and fenofibrate to simvastatin and gemfibrozil.

Original language	English (US)
Pages (from-to)	127-128
Number of pages	2
Journal	Cardiology
Volume	94
Issue number	2
DOIs	https://doi.org/10.1159/000047304
State	Published - Dec 1 2000

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine
Pharmacology (medical)

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10.1159/000047304

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abstract = "Statin-fibrate combinations are commonly used to treat hyperlipidemia. These drugs have been previously reported to cause rhabdomyolysis with acute renal failure. Whether different statin-fibrate combinations have different risks for rhabdomyolysis is not known. We report a patient who developed rhabdomyolysis with acute renal failure pomptly after switching from the combination of pravastatin and fenofibrate to simvastatin and gemfibrozil.",

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AU - Lund, Richard J.

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AU - Meares, A. John

AU - Dunlay, Robert

PY - 2000/12/1

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AB - Statin-fibrate combinations are commonly used to treat hyperlipidemia. These drugs have been previously reported to cause rhabdomyolysis with acute renal failure. Whether different statin-fibrate combinations have different risks for rhabdomyolysis is not known. We report a patient who developed rhabdomyolysis with acute renal failure pomptly after switching from the combination of pravastatin and fenofibrate to simvastatin and gemfibrozil.

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Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations

Abstract

All Science Journal Classification (ASJC) codes

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