Role of dietary sodium in osteoporosis

Robert P. Heaney

Research output: Contribution to journalReview article

100 Citations (Scopus)

Abstract

Sodium, in the form of sodium chloride, elevates urinary calcium excretion and, at prevailing calcium intakes, evokes compensatory responses that may lead to increased bone remodeling and bone loss. The calciuria is partly due to salt-induced volume expansion, with an increase in GFR, and partly to competition between sodium and calcium ions in the renal tubule. Potassium intakes in the range of current recommendations actually reduce or prevent sodium chloride-induced calciuria. At calcium intakes at or above currently recommended levels, there appear to be no deleterious effects of prevailing salt intakes on bone or the calcium economy, mainly because adaptive increases in calcium absorption offset the increased urinary loss. Such compensation is likely to be incomplete at low calcium intakes. Limited evidence suggests equivalent bone-sparing effects of either salt restriction or augmented calcium intakes. Given the relative difficulty of the former, and the ancillary benefits of the latter, it would seem that the optimal strategy to protect the skeleton is to ensure adequate calcium and potassium intakes.

Original languageEnglish
JournalJournal of the American College of Nutrition
Volume25
Issue number3 SUPPL.
StatePublished - 2006

Fingerprint

Dietary Sodium
osteoporosis
Osteoporosis
sodium
Calcium
calcium
bones
Salts
Bone and Bones
Sodium Chloride
sodium chloride
Potassium
Sodium
potassium
low sodium diet
salts
renal tubules
Bone Remodeling
Skeleton
skeleton

All Science Journal Classification (ASJC) codes

  • Food Science
  • Medicine (miscellaneous)

Cite this

Role of dietary sodium in osteoporosis. / Heaney, Robert P.

In: Journal of the American College of Nutrition, Vol. 25, No. 3 SUPPL., 2006.

Research output: Contribution to journalReview article

Heaney, Robert P. / Role of dietary sodium in osteoporosis. In: Journal of the American College of Nutrition. 2006 ; Vol. 25, No. 3 SUPPL.
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