Role of gastrointestinal permeability in exertional heatstroke

Research output: Contribution to journalReview articlepeer-review

109 Scopus citations


Reduced splanchnic blood flow and hyperthermia during exercise-heat stress can produce gastrointestinal barrier dysfunction and increased gastrointestinal permeability. This may allow endotoxin to enter the internal environment, causing local and systemic immune responses. These responses may be involved in the cause and outcome of exertional heatstroke. Countermeasures may reduce gastrointestinal permeability and possibly exertional heatstroke occurrence and outcome.

Original languageEnglish (US)
Pages (from-to)185-190
Number of pages6
JournalExercise and Sport Sciences Reviews
Issue number4
StatePublished - Oct 2004

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation


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