Role of Vitamin D in Cardiovascular Diseases

Vikrant Rai, Devendra K. Agrawal

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Vitamin D is critical in mineral homeostasis and skeletal health and plays a regulatory role in nonskeletal tissues. Vitamin D deficiency is associated with chronic inflammatory diseases, including diabetes and obesity, both strong risk factors for cardiovascular diseases (CVDs). CVDs, including coronary artery disease, myocardial infarction, hypertrophy, cardiomyopathy, cardiac fibrosis, heart failure, aneurysm, peripheral arterial disease, hypertension, and atherosclerosis, are major causes of morbidity and mortality. The association of these diseases with vitamin D deficiency and improvement with vitamin D supplementation suggest its therapeutic benefit. The authors review the findings on the association of vitamin D deficiency and CVDs.

Original languageEnglish (US)
Pages (from-to)1039-1059
Number of pages21
JournalEndocrinology and Metabolism Clinics of North America
Volume46
Issue number4
DOIs
StatePublished - Dec 1 2017

Fingerprint

Vitamin D Deficiency
Vitamin D
Cardiovascular Diseases
Heart Aneurysm
Deficiency Diseases
Peripheral Arterial Disease
Cardiomegaly
Cardiomyopathies
Minerals
Coronary Artery Disease
Atherosclerosis
Homeostasis
Fibrosis
Chronic Disease
Heart Failure
Obesity
Myocardial Infarction
Hypertension
Morbidity
Mortality

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Role of Vitamin D in Cardiovascular Diseases. / Rai, Vikrant; Agrawal, Devendra K.

In: Endocrinology and Metabolism Clinics of North America, Vol. 46, No. 4, 01.12.2017, p. 1039-1059.

Research output: Contribution to journalReview article

@article{9dfdb0ecb751479e9e3506a98e5691e2,
title = "Role of Vitamin D in Cardiovascular Diseases",
abstract = "Vitamin D is critical in mineral homeostasis and skeletal health and plays a regulatory role in nonskeletal tissues. Vitamin D deficiency is associated with chronic inflammatory diseases, including diabetes and obesity, both strong risk factors for cardiovascular diseases (CVDs). CVDs, including coronary artery disease, myocardial infarction, hypertrophy, cardiomyopathy, cardiac fibrosis, heart failure, aneurysm, peripheral arterial disease, hypertension, and atherosclerosis, are major causes of morbidity and mortality. The association of these diseases with vitamin D deficiency and improvement with vitamin D supplementation suggest its therapeutic benefit. The authors review the findings on the association of vitamin D deficiency and CVDs.",
author = "Vikrant Rai and Agrawal, {Devendra K.}",
year = "2017",
month = "12",
day = "1",
doi = "10.1016/j.ecl.2017.07.009",
language = "English (US)",
volume = "46",
pages = "1039--1059",
journal = "Endocrinology and Metabolism Clinics of North America",
issn = "0889-8529",
publisher = "W.B. Saunders Ltd",
number = "4",

}

TY - JOUR

T1 - Role of Vitamin D in Cardiovascular Diseases

AU - Rai, Vikrant

AU - Agrawal, Devendra K.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Vitamin D is critical in mineral homeostasis and skeletal health and plays a regulatory role in nonskeletal tissues. Vitamin D deficiency is associated with chronic inflammatory diseases, including diabetes and obesity, both strong risk factors for cardiovascular diseases (CVDs). CVDs, including coronary artery disease, myocardial infarction, hypertrophy, cardiomyopathy, cardiac fibrosis, heart failure, aneurysm, peripheral arterial disease, hypertension, and atherosclerosis, are major causes of morbidity and mortality. The association of these diseases with vitamin D deficiency and improvement with vitamin D supplementation suggest its therapeutic benefit. The authors review the findings on the association of vitamin D deficiency and CVDs.

AB - Vitamin D is critical in mineral homeostasis and skeletal health and plays a regulatory role in nonskeletal tissues. Vitamin D deficiency is associated with chronic inflammatory diseases, including diabetes and obesity, both strong risk factors for cardiovascular diseases (CVDs). CVDs, including coronary artery disease, myocardial infarction, hypertrophy, cardiomyopathy, cardiac fibrosis, heart failure, aneurysm, peripheral arterial disease, hypertension, and atherosclerosis, are major causes of morbidity and mortality. The association of these diseases with vitamin D deficiency and improvement with vitamin D supplementation suggest its therapeutic benefit. The authors review the findings on the association of vitamin D deficiency and CVDs.

UR - http://www.scopus.com/inward/record.url?scp=85030455455&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85030455455&partnerID=8YFLogxK

U2 - 10.1016/j.ecl.2017.07.009

DO - 10.1016/j.ecl.2017.07.009

M3 - Review article

VL - 46

SP - 1039

EP - 1059

JO - Endocrinology and Metabolism Clinics of North America

JF - Endocrinology and Metabolism Clinics of North America

SN - 0889-8529

IS - 4

ER -