Role of Vitamin D in Cardiovascular Diseases

Vikrant Rai, Devendra K. Agrawal

Research output: Contribution to journalReview article

18 Scopus citations

Abstract

Vitamin D is critical in mineral homeostasis and skeletal health and plays a regulatory role in nonskeletal tissues. Vitamin D deficiency is associated with chronic inflammatory diseases, including diabetes and obesity, both strong risk factors for cardiovascular diseases (CVDs). CVDs, including coronary artery disease, myocardial infarction, hypertrophy, cardiomyopathy, cardiac fibrosis, heart failure, aneurysm, peripheral arterial disease, hypertension, and atherosclerosis, are major causes of morbidity and mortality. The association of these diseases with vitamin D deficiency and improvement with vitamin D supplementation suggest its therapeutic benefit. The authors review the findings on the association of vitamin D deficiency and CVDs.

Original languageEnglish (US)
Pages (from-to)1039-1059
Number of pages21
JournalEndocrinology and Metabolism Clinics of North America
Volume46
Issue number4
DOIs
StatePublished - Dec 1 2017

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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