Safety of Bisphosphonates in the Treatment of Osteoporosis

Robert R. Recker; E. Michael Lewiecki; Paul D. Miller; James Reiffel

doi:10.1016/j.amjmed.2008.12.004

Safety of Bisphosphonates in the Treatment of Osteoporosis

Robert R. Recker, E. Michael Lewiecki, Paul D. Miller, James Reiffel

Department of Medicine

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Abstract

In this review 4 experts consider the major safety concerns relating to bisphosphonate therapy for osteoporosis. Specific topics covered are skeletal safety (particularly with respect to atypical fractures and delayed healing), gastrointestinal intolerance, hypocalcemia, acute-phase (i.e., postdose) reactions, chronic musculoskeletal pain, renal safety, and cardiovascular safety (specifically, atrial fibrillation).

Original language	English (US)
Pages (from-to)	S22-S32
Journal	American Journal of Medicine
Volume	122
Issue number	2 SUPPL.
DOIs	https://doi.org/10.1016/j.amjmed.2008.12.004
State	Published - Feb 3 2009

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1016/j.amjmed.2008.12.004

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abstract = "In this review 4 experts consider the major safety concerns relating to bisphosphonate therapy for osteoporosis. Specific topics covered are skeletal safety (particularly with respect to atypical fractures and delayed healing), gastrointestinal intolerance, hypocalcemia, acute-phase (i.e., postdose) reactions, chronic musculoskeletal pain, renal safety, and cardiovascular safety (specifically, atrial fibrillation).",

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