SEASONAL VARIATION OF HISTOLOGICAL OSTEOMALACIA IN FEMORAL-NECK FRACTURES

J. E. Aaron; J. C. Gallagher; B. E.C. Nordin

doi:10.1016/S0140-6736(74)91640-7

SEASONAL VARIATION OF HISTOLOGICAL OSTEOMALACIA IN FEMORAL-NECK FRACTURES

J. E. Aaron, J. C. Gallagher, B. E.C. Nordin

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

In a series of 134 iliac-crest biopsies from unselected cases of fracture of the proximal femur, the proportion with evidence of osteomalacia varied with the season. The highest frequency of abnormal calcification fronts (43%) was observed in February to April and the lowest (15%) in August to October. The highest frequency of abnormal osteoid-covered surfaces (47%) was observed in April to June and the lowest (13%) in October to December. The overall frequency of osteomalacia in femoral-neck-fracture cases in Leeds seems to be about 37%. It is concluded that variation in hours of sunshine is responsible for a seasonal variation in osteomalacia in these cases and, possibly, in the elderly population as a whole.

Original language	English (US)
Pages (from-to)	84-85
Number of pages	2
Journal	The Lancet
Volume	304
Issue number	7872
DOIs	https://doi.org/10.1016/S0140-6736(74)91640-7
State	Published - Jul 13 1974
Externally published	Yes

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1016/S0140-6736(74)91640-7

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title = "SEASONAL VARIATION OF HISTOLOGICAL OSTEOMALACIA IN FEMORAL-NECK FRACTURES",

abstract = "In a series of 134 iliac-crest biopsies from unselected cases of fracture of the proximal femur, the proportion with evidence of osteomalacia varied with the season. The highest frequency of abnormal calcification fronts (43%) was observed in February to April and the lowest (15%) in August to October. The highest frequency of abnormal osteoid-covered surfaces (47%) was observed in April to June and the lowest (13%) in October to December. The overall frequency of osteomalacia in femoral-neck-fracture cases in Leeds seems to be about 37%. It is concluded that variation in hours of sunshine is responsible for a seasonal variation in osteomalacia in these cases and, possibly, in the elderly population as a whole.",

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AB - In a series of 134 iliac-crest biopsies from unselected cases of fracture of the proximal femur, the proportion with evidence of osteomalacia varied with the season. The highest frequency of abnormal calcification fronts (43%) was observed in February to April and the lowest (15%) in August to October. The highest frequency of abnormal osteoid-covered surfaces (47%) was observed in April to June and the lowest (13%) in October to December. The overall frequency of osteomalacia in femoral-neck-fracture cases in Leeds seems to be about 37%. It is concluded that variation in hours of sunshine is responsible for a seasonal variation in osteomalacia in these cases and, possibly, in the elderly population as a whole.

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