Abstract
Cutaneous lesions consonant with Muir-Torre syndrome strongly suggest hereditary non-polyposis colorectal cancer (HNPCC). Ponti et al. discuss the importance of combining molecular genetic features of the sebaceous neoplasms, including microsatellite instability and immunohistochemistry, with family history, to determine the likelihood of HNPCC. Proof of diagnosis is identification of one of the mismatch repair germline mutations.
Original language | English (US) |
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Pages (from-to) | 2158-2159 |
Number of pages | 2 |
Journal | Journal of Investigative Dermatology |
Volume | 126 |
Issue number | 10 |
DOIs |
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State | Published - Oct 30 2006 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
- Dermatology
- Cell Biology