Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer

Henry T. Lynch; Ramon M. Fusaro; Patrick M. Lynch

doi:10.1038/sj.jid.5700534

Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer

Henry T. Lynch, Ramon M. Fusaro, Patrick M. Lynch

Department of Preventive Medicine

13 Scopus citations

Abstract

Cutaneous lesions consonant with Muir-Torre syndrome strongly suggest hereditary non-polyposis colorectal cancer (HNPCC). Ponti et al. discuss the importance of combining molecular genetic features of the sebaceous neoplasms, including microsatellite instability and immunohistochemistry, with family history, to determine the likelihood of HNPCC. Proof of diagnosis is identification of one of the mismatch repair germline mutations.

Original language	English
Pages (from-to)	2158-2159
Number of pages	2
Journal	Journal of Investigative Dermatology
Volume	126
Issue number	10
DOIs	https://doi.org/10.1038/sj.jid.5700534
Publication status	Published - Oct 30 2006

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All Science Journal Classification (ASJC) codes

Dermatology

Cite this

Lynch, H. T., Fusaro, R. M., & Lynch, P. M. (2006). Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer. Journal of Investigative Dermatology, 126(10), 2158-2159. https://doi.org/10.1038/sj.jid.5700534

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10.1038/sj.jid.5700534