Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer

Henry T. Lynch; Ramon M. Fusaro; Patrick M. Lynch

doi:10.1038/sj.jid.5700534

Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer

Henry T. Lynch, Ramon M. Fusaro, Patrick M. Lynch

Department of Preventive Medicine

Research output: Contribution to journal › Comment/debate › peer-review

13 Scopus citations

Abstract

Cutaneous lesions consonant with Muir-Torre syndrome strongly suggest hereditary non-polyposis colorectal cancer (HNPCC). Ponti et al. discuss the importance of combining molecular genetic features of the sebaceous neoplasms, including microsatellite instability and immunohistochemistry, with family history, to determine the likelihood of HNPCC. Proof of diagnosis is identification of one of the mismatch repair germline mutations.

Original language	English (US)
Pages (from-to)	2158-2159
Number of pages	2
Journal	Journal of Investigative Dermatology
Volume	126
Issue number	10
DOIs	https://doi.org/10.1038/sj.jid.5700534
State	Published - Oct 30 2006

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Dermatology
Cell Biology

Access to Document

10.1038/sj.jid.5700534

Cite this

@article{650001c6955d4a42b4b7dc5f188d93ed,

title = "Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer",

abstract = "Cutaneous lesions consonant with Muir-Torre syndrome strongly suggest hereditary non-polyposis colorectal cancer (HNPCC). Ponti et al. discuss the importance of combining molecular genetic features of the sebaceous neoplasms, including microsatellite instability and immunohistochemistry, with family history, to determine the likelihood of HNPCC. Proof of diagnosis is identification of one of the mismatch repair germline mutations.",

author = "Lynch, {Henry T.} and Fusaro, {Ramon M.} and Lynch, {Patrick M.}",

year = "2006",

month = oct,

day = "30",

doi = "10.1038/sj.jid.5700534",

language = "English (US)",

volume = "126",

pages = "2158--2159",

journal = "Journal of Investigative Dermatology",

issn = "0022-202X",

publisher = "Nature Publishing Group",

number = "10",

}

TY - JOUR

T1 - Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer

AU - Lynch, Henry T.

AU - Fusaro, Ramon M.

AU - Lynch, Patrick M.

PY - 2006/10/30

Y1 - 2006/10/30

N2 - Cutaneous lesions consonant with Muir-Torre syndrome strongly suggest hereditary non-polyposis colorectal cancer (HNPCC). Ponti et al. discuss the importance of combining molecular genetic features of the sebaceous neoplasms, including microsatellite instability and immunohistochemistry, with family history, to determine the likelihood of HNPCC. Proof of diagnosis is identification of one of the mismatch repair germline mutations.

AB - Cutaneous lesions consonant with Muir-Torre syndrome strongly suggest hereditary non-polyposis colorectal cancer (HNPCC). Ponti et al. discuss the importance of combining molecular genetic features of the sebaceous neoplasms, including microsatellite instability and immunohistochemistry, with family history, to determine the likelihood of HNPCC. Proof of diagnosis is identification of one of the mismatch repair germline mutations.

UR - http://www.scopus.com/inward/record.url?scp=33748759802&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748759802&partnerID=8YFLogxK

U2 - 10.1038/sj.jid.5700534

DO - 10.1038/sj.jid.5700534

M3 - Comment/debate

C2 - 16983324

AN - SCOPUS:33748759802

VL - 126

SP - 2158

EP - 2159

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

SN - 0022-202X

IS - 10

ER -

Sebaceous skin lesions as clues to hereditary non-polyposis colorectal cancer

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this