Selective cycloalkanone reductions using aluminum amalgam

Martin Hulce, Timothy LaVaute

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Aluminum amalgam in aqueous tetrahydrofuran reduces cycloalkanones to their respective alcohols. The reaction exhibits sensitivity to the ring size and steric environment of the ketone.

Original languageEnglish
Pages (from-to)525-528
Number of pages4
JournalTetrahedron Letters
Volume29
Issue number5
DOIs
Publication statusPublished - 1988
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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