Selective Sirt2 inhibition by ligand-induced rearrangement of the active site

Tobias Rumpf, Matthias Schiedel, Berin Karaman, Claudia Roessler, Brian J. North, Attila Lehotzky, Judit Oláh, Kathrin I. Ladwein, Karin Schmidtkunz, Markus Gajer, Martin Pannek, Clemens Steegborn, David A. Sinclair, Stefan Gerhardt, Judit Ovádi, Mike Schutkowski, Wolfgang Sippl, Oliver Einsle, Manfred Jung