Sentinel lymphadenectomy in the management of primary cutaneous malignant melanoma: An update

W. L. White, Brian W. Loggie

Research output: Contribution to journalReview article

8 Scopus citations


The management of lymph nodes in melanoma patients who have no clinical evidence of nodal disease has changed dramatically with the development of selective lymph node biopsy. This procedure localizes the node in a regional basin most likely to contain a metastasis (the sentinel node) and averts the morbidity of unnecessary elective node dissection. This update reviews the rationale for this procedure and describes the methodology used by the surgeon and the pathologist. A progress report highlights the promise and limitation of this procedure. Sentinel node biopsy is currently the standard for staging select groups of melanoma patients, but the field is rapidly evolving and may eventually be surpassed by even newer molecular diagnostic techniques.

Original languageEnglish
Pages (from-to)645-655
Number of pages11
JournalDermatologic Clinics
Issue number3
Publication statusPublished - 1999
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Dermatology

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