Abstract
An efficient strategy for the synthesis of indolizines from readily available starting materials via oxidative C-H functionalization and 5-endo-dig cyclization in one step has been demonstrated. This protocol represents wide substrate scope, high functional group tolerance, and selectivity. The structure of the product was confirmed by X-ray crystallographic studies. Ag2CO3 required of this tandem reaction can be recycled and reused after undergoing oxidative reaction.
| Original language | English |
|---|---|
| Pages (from-to) | 6922-6924 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 55 |
| Issue number | 50 |
| DOIs | |
| State | Published - Dec 10 2014 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Silver-mediated synthesis of indolizines via oxidative C-H functionalization and 5-endo-dig cyclization. / Pandya, Amit N.; Fletcher, James T.; Villa, Eric; Agrawal, Devendra K.
In: Tetrahedron Letters, Vol. 55, No. 50, 10.12.2014, p. 6922-6924.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Silver-mediated synthesis of indolizines via oxidative C-H functionalization and 5-endo-dig cyclization
AU - Pandya, Amit N.
AU - Fletcher, James T.
AU - Villa, Eric
AU - Agrawal, Devendra K.
PY - 2014/12/10
Y1 - 2014/12/10
N2 - An efficient strategy for the synthesis of indolizines from readily available starting materials via oxidative C-H functionalization and 5-endo-dig cyclization in one step has been demonstrated. This protocol represents wide substrate scope, high functional group tolerance, and selectivity. The structure of the product was confirmed by X-ray crystallographic studies. Ag2CO3 required of this tandem reaction can be recycled and reused after undergoing oxidative reaction.
AB - An efficient strategy for the synthesis of indolizines from readily available starting materials via oxidative C-H functionalization and 5-endo-dig cyclization in one step has been demonstrated. This protocol represents wide substrate scope, high functional group tolerance, and selectivity. The structure of the product was confirmed by X-ray crystallographic studies. Ag2CO3 required of this tandem reaction can be recycled and reused after undergoing oxidative reaction.
UR - http://www.scopus.com/inward/record.url?scp=84910603429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84910603429&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2014.10.112
DO - 10.1016/j.tetlet.2014.10.112
M3 - Article
AN - SCOPUS:84910603429
VL - 55
SP - 6922
EP - 6924
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 50
ER -