Abstract
An efficient strategy for the synthesis of indolizines from readily available starting materials via oxidative C-H functionalization and 5-endo-dig cyclization in one step has been demonstrated. This protocol represents wide substrate scope, high functional group tolerance, and selectivity. The structure of the product was confirmed by X-ray crystallographic studies. Ag2CO3 required of this tandem reaction can be recycled and reused after undergoing oxidative reaction.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6922-6924 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 55 |
| Issue number | 50 |
| DOIs | |
| State | Published - Dec 10 2014 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Pandya, A. N., Fletcher, J. T., Villa, E. M., & Agrawal, D. K. (2014). Silver-mediated synthesis of indolizines via oxidative C-H functionalization and 5-endo-dig cyclization. Tetrahedron Letters, 55(50), 6922-6924. https://doi.org/10.1016/j.tetlet.2014.10.112