TY - GEN
T1 - Spatially and Spectrally Resolved Steady-State Diffuse Reflectance Measurements of the Optical Properties of Tissue-Simulating Phantoms
AU - Nichols, M. G.
AU - Hull, E. L.
AU - Foster, T. H.
N1 - Funding Information:
This research was supported by a grant from the Whitaker Foundation. ’Ihe authors wish to thank Mike Patterson, Tom Farrell, Brian Wilson, and Joe Hayward for many helpful discussions and insights concerning the practice of diffuse reflectance spectroscopy.
Publisher Copyright:
© 1996 Optical Society of America.
PY - 1996
Y1 - 1996
N2 - We have constructed a steady-state radially-resolved diffuse reflectance spectrometer capable of simultaneously measuring the absorption (μa) and transport scattering (μs') spectra of tissue-simulating phantoms within an adjustable 160 nm wavelength interval. We present absorption and transport scattering spectra of various tissue-simulating phantoms reconstructed from diffuse reflectance measurements. When compared with the known optical properties of the phantoms, the returned optical coefficients are generally found to be accurate to within 10% for media in which the diffusion model of photon transport is relevant. In addition, Monte Carlo simulations are presented which illustrate the dependence of the errors in the returned optical properties on the source-detector separation distances used in the measurement. Finally, we discuss determinations of hemoglobin oxygen saturation derived from diffuse reflectance measurements of tissue-simulating phantoms.
AB - We have constructed a steady-state radially-resolved diffuse reflectance spectrometer capable of simultaneously measuring the absorption (μa) and transport scattering (μs') spectra of tissue-simulating phantoms within an adjustable 160 nm wavelength interval. We present absorption and transport scattering spectra of various tissue-simulating phantoms reconstructed from diffuse reflectance measurements. When compared with the known optical properties of the phantoms, the returned optical coefficients are generally found to be accurate to within 10% for media in which the diffusion model of photon transport is relevant. In addition, Monte Carlo simulations are presented which illustrate the dependence of the errors in the returned optical properties on the source-detector separation distances used in the measurement. Finally, we discuss determinations of hemoglobin oxygen saturation derived from diffuse reflectance measurements of tissue-simulating phantoms.
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M3 - Conference contribution
AN - SCOPUS:85135511711
T3 - Optics InfoBase Conference Papers
SP - 50
EP - 54
BT - Biomedical Optical Spectroscopy and Diagnostics, BOSD 1996
PB - Optica Publishing Group (formerly OSA)
T2 - Biomedical Optical Spectroscopy and Diagnostics, BOSD 1996
Y2 - 1 January 1996 through 18 March 1996
ER -