Spatially and Spectrally Resolved Steady-State Diffuse Reflectance Measurements of the Optical Properties of Tissue-Simulating Phantoms

M. G. Nichols, E. L. Hull, T. H. Foster

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

We have constructed a steady-state radially-resolved diffuse reflectance spectrometer capable of simultaneously measuring the absorption (μa) and transport scattering (μs') spectra of tissue-simulating phantoms within an adjustable 160 nm wavelength interval. We present absorption and transport scattering spectra of various tissue-simulating phantoms reconstructed from diffuse reflectance measurements. When compared with the known optical properties of the phantoms, the returned optical coefficients are generally found to be accurate to within 10% for media in which the diffusion model of photon transport is relevant. In addition, Monte Carlo simulations are presented which illustrate the dependence of the errors in the returned optical properties on the source-detector separation distances used in the measurement. Finally, we discuss determinations of hemoglobin oxygen saturation derived from diffuse reflectance measurements of tissue-simulating phantoms.

Original languageEnglish (US)
Title of host publicationBiomedical Optical Spectroscopy and Diagnostics, BOSD 1996
PublisherOptica Publishing Group (formerly OSA)
Pages50-54
Number of pages5
ISBN (Electronic)9781557528209
StatePublished - 1996
Externally publishedYes
EventBiomedical Optical Spectroscopy and Diagnostics, BOSD 1996 - Orlando, United States
Duration: Jan 1 1996Mar 18 1996

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceBiomedical Optical Spectroscopy and Diagnostics, BOSD 1996
Country/TerritoryUnited States
CityOrlando
Period1/1/963/18/96

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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