Statin Therapy and Hemodialysis Vascular Access-Were We Bringing a Knife to a Gunfight and Were Hoping to Win?

Marius C. Florescu, Nathan Birch

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Vascular access dysfunction is a major contributor to end stage renal disease patient morbidity, and the cost of maintaining it is staggering. Any intervention able to improve the vascular access maturation rate and/or patency would be significant progress. Based on the anti-inflammatory and vascular beneficial effects demonstrated in non-end stage renal disease patients, we were hoping that statin use might provide the much needed improvement in the hemodialysis vascular access outcome. The reality proved disappointing. The statins failed to improve every aspect of hemodialysis vascular access studied. The present editorial discusses the current data regarding the effect of statins on vascular access and attempts to explain their lack of success.

Original languageEnglish (US)
Pages (from-to)700-702
Number of pages3
JournalSeminars in Dialysis
Volume25
Issue number6
DOIs
StatePublished - Nov 1 2012
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Nephrology

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