Statins as antiarrhythmics

A systematic review part II: Effects on risk of ventricular arrhythmias

Hussam Abuissa, James H. O'Keefe, Kevin A. Bybee

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

Background: Recent studies have demonstrated that statins may possess antiarrhythmic properties in addition to their lipid-lowering effects. Methods: Studies which reported the association of statins with the incidence of ventricular arrhythmias were identified through a systematic review of the published literature. Results: Statins have been associated with significant reduction in ventricular arrhythmia in cardiomyopathy patients with an implantable cardioverter defibrillator, although randomized trials have not been completed. Conclusions: Published data suggest that statins may possess antiarrhythmic properties that reduce the propensity for ventricular arrhythmias. Most of this data is observational; more randomized, placebo-controlled trials are needed.

Original languageEnglish
Pages (from-to)549-552
Number of pages4
JournalClinical Cardiology
Volume32
Issue number10
DOIs
StatePublished - 2009
Externally publishedYes

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Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiac Arrhythmias
Implantable Defibrillators
Cardiomyopathies
Randomized Controlled Trials
Placebos
Lipids
Incidence

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Statins as antiarrhythmics : A systematic review part II: Effects on risk of ventricular arrhythmias. / Abuissa, Hussam; O'Keefe, James H.; Bybee, Kevin A.

In: Clinical Cardiology, Vol. 32, No. 10, 2009, p. 549-552.

Research output: Contribution to journalReview article

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