Statins as antiarrhythmics: A systematic review part II: Effects on risk of ventricular arrhythmias

Hussam Abuissa, James H. O'Keefe, Kevin A. Bybee

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

Background: Recent studies have demonstrated that statins may possess antiarrhythmic properties in addition to their lipid-lowering effects. Methods: Studies which reported the association of statins with the incidence of ventricular arrhythmias were identified through a systematic review of the published literature. Results: Statins have been associated with significant reduction in ventricular arrhythmia in cardiomyopathy patients with an implantable cardioverter defibrillator, although randomized trials have not been completed. Conclusions: Published data suggest that statins may possess antiarrhythmic properties that reduce the propensity for ventricular arrhythmias. Most of this data is observational; more randomized, placebo-controlled trials are needed.

Original languageEnglish (US)
Pages (from-to)549-552
Number of pages4
JournalClinical Cardiology
Volume32
Issue number10
DOIs
StatePublished - 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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