Abstract
Background: Recent studies have demonstrated that statins may possess antiarrhythmic properties in addition to their lipid-lowering effects. Methods: Studies which reported the association of statins with the incidence of ventricular arrhythmias were identified through a systematic review of the published literature. Results: Statins have been associated with significant reduction in ventricular arrhythmia in cardiomyopathy patients with an implantable cardioverter defibrillator, although randomized trials have not been completed. Conclusions: Published data suggest that statins may possess antiarrhythmic properties that reduce the propensity for ventricular arrhythmias. Most of this data is observational; more randomized, placebo-controlled trials are needed.
Original language | English (US) |
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Pages (from-to) | 549-552 |
Number of pages | 4 |
Journal | Clinical Cardiology |
Volume | 32 |
Issue number | 10 |
DOIs | |
State | Published - 2009 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine