Surveillance of carbapenem-resistant pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals

Dissemination of KPC and IMP-18 β-lactamases

Daniel J. Wolter, Noha Khalaf, Iraida E. Robledo, J. Guillermo Vázquez, I. Maria Santé, Edna E. Aquino, Richard V. Goering, Nancy D. Hanson

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

During a 6-month period, 37/513 (7.2%) Pseudomonas aeruginosa isolates belonging to 13 pulsed-fleld gel electrophoresis (PFGE) groups from Puerto Rican hospitals were carbapenem nonsusceptible. Seven of 37 isolates from four PFGE groups carried blaIMP.1B, and 25/37 isolates from seven PFGE groups carried blaKPC. The results indicated the clonal spread of WaKPC-positive P. aeruginosa isolates into several Puerto Rican hospitals and the dissemination of blaIMPmls and blaKPC into genetically unrelated isolates.

Original languageEnglish
Pages (from-to)1660-1664
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number4
DOIs
StatePublished - Apr 2009

Fingerprint

Inosine Monophosphate
Carbapenems
Pseudomonas aeruginosa
Electrophoresis
Gels

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

Cite this

Surveillance of carbapenem-resistant pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals : Dissemination of KPC and IMP-18 β-lactamases. / Wolter, Daniel J.; Khalaf, Noha; Robledo, Iraida E.; Vázquez, J. Guillermo; Santé, I. Maria; Aquino, Edna E.; Goering, Richard V.; Hanson, Nancy D.

In: Antimicrobial Agents and Chemotherapy, Vol. 53, No. 4, 04.2009, p. 1660-1664.

Research output: Contribution to journalArticle

Wolter, Daniel J. ; Khalaf, Noha ; Robledo, Iraida E. ; Vázquez, J. Guillermo ; Santé, I. Maria ; Aquino, Edna E. ; Goering, Richard V. ; Hanson, Nancy D. / Surveillance of carbapenem-resistant pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals : Dissemination of KPC and IMP-18 β-lactamases. In: Antimicrobial Agents and Chemotherapy. 2009 ; Vol. 53, No. 4. pp. 1660-1664.
@article{ef03ccbfd69643e3808e56bd6cbab811,
title = "Surveillance of carbapenem-resistant pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals: Dissemination of KPC and IMP-18 β-lactamases",
abstract = "During a 6-month period, 37/513 (7.2{\%}) Pseudomonas aeruginosa isolates belonging to 13 pulsed-fleld gel electrophoresis (PFGE) groups from Puerto Rican hospitals were carbapenem nonsusceptible. Seven of 37 isolates from four PFGE groups carried blaIMP.1B, and 25/37 isolates from seven PFGE groups carried blaKPC. The results indicated the clonal spread of WaKPC-positive P. aeruginosa isolates into several Puerto Rican hospitals and the dissemination of blaIMPmls and blaKPC into genetically unrelated isolates.",
author = "Wolter, {Daniel J.} and Noha Khalaf and Robledo, {Iraida E.} and V{\'a}zquez, {J. Guillermo} and Sant{\'e}, {I. Maria} and Aquino, {Edna E.} and Goering, {Richard V.} and Hanson, {Nancy D.}",
year = "2009",
month = "4",
doi = "10.1128/AAC.01172-08",
language = "English",
volume = "53",
pages = "1660--1664",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "4",

}

TY - JOUR

T1 - Surveillance of carbapenem-resistant pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals

T2 - Dissemination of KPC and IMP-18 β-lactamases

AU - Wolter, Daniel J.

AU - Khalaf, Noha

AU - Robledo, Iraida E.

AU - Vázquez, J. Guillermo

AU - Santé, I. Maria

AU - Aquino, Edna E.

AU - Goering, Richard V.

AU - Hanson, Nancy D.

PY - 2009/4

Y1 - 2009/4

N2 - During a 6-month period, 37/513 (7.2%) Pseudomonas aeruginosa isolates belonging to 13 pulsed-fleld gel electrophoresis (PFGE) groups from Puerto Rican hospitals were carbapenem nonsusceptible. Seven of 37 isolates from four PFGE groups carried blaIMP.1B, and 25/37 isolates from seven PFGE groups carried blaKPC. The results indicated the clonal spread of WaKPC-positive P. aeruginosa isolates into several Puerto Rican hospitals and the dissemination of blaIMPmls and blaKPC into genetically unrelated isolates.

AB - During a 6-month period, 37/513 (7.2%) Pseudomonas aeruginosa isolates belonging to 13 pulsed-fleld gel electrophoresis (PFGE) groups from Puerto Rican hospitals were carbapenem nonsusceptible. Seven of 37 isolates from four PFGE groups carried blaIMP.1B, and 25/37 isolates from seven PFGE groups carried blaKPC. The results indicated the clonal spread of WaKPC-positive P. aeruginosa isolates into several Puerto Rican hospitals and the dissemination of blaIMPmls and blaKPC into genetically unrelated isolates.

UR - http://www.scopus.com/inward/record.url?scp=65649116984&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=65649116984&partnerID=8YFLogxK

U2 - 10.1128/AAC.01172-08

DO - 10.1128/AAC.01172-08

M3 - Article

VL - 53

SP - 1660

EP - 1664

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 4

ER -