Surveillance of carbapenem-resistant pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals: Dissemination of KPC and IMP-18 β-lactamases

Daniel J. Wolter, Noha Khalaf, Iraida E. Robledo, J. Guillermo Vázquez, I. Maria Santé, Edna E. Aquino, Richard V. Goering, Nancy D. Hanson

Research output: Contribution to journalArticle

62 Scopus citations


During a 6-month period, 37/513 (7.2%) Pseudomonas aeruginosa isolates belonging to 13 pulsed-fleld gel electrophoresis (PFGE) groups from Puerto Rican hospitals were carbapenem nonsusceptible. Seven of 37 isolates from four PFGE groups carried blaIMP.1B, and 25/37 isolates from seven PFGE groups carried blaKPC. The results indicated the clonal spread of WaKPC-positive P. aeruginosa isolates into several Puerto Rican hospitals and the dissemination of blaIMPmls and blaKPC into genetically unrelated isolates.

Original languageEnglish (US)
Pages (from-to)1660-1664
Number of pages5
JournalAntimicrobial agents and chemotherapy
Issue number4
StatePublished - Apr 1 2009


All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Cite this