Abstract
West Nile virus (WNV) spread to the US western plains states in 2003, when a significant mortality event attributed to WNV occurred in Greater Sage-grouse (Centrocercus urophasianus). The role of avian species inhabiting sagebrush in the amplification of WNV in arid and semiarid regions of the North America is unknown. We conducted an experimental WNV challenge study in Vesper Sparrows (Pooecetes gramineus), a species common to sagebrush and grassland habitats found throughout much of North America. We found Vesper Sparrows to be moderately susceptible to WNV, developing viremia considered sufficient to transmit WNV to feeding mosquitoes, but the majority of birds were capable of surviving infection and developing a humoral immune response to the WNV nonstructural 1 and envelope proteins. Despite clearance of viremia, after 6 mo, WNV was detected molecularly in three birds and cultured from one bird. Surviving Vesper Sparrows were resistant to reinfection 6 mo after the initial challenge. Vesper sparrows could play a role in the amplification of WNV in sagebrush habitat and other areas of their range, but rapid clearance of WNV may limit their importance as competent amplification hosts of WNV.
| Original language | English |
|---|---|
| Pages (from-to) | 345-353 |
| Number of pages | 9 |
| Journal | Journal of Wildlife Diseases |
| Volume | 52 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1 2016 |
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All Science Journal Classification (ASJC) codes
- Ecology, Evolution, Behavior and Systematics
- Ecology
Cite this
Susceptibility and antibody response of vesper sparrows (Pooecetes gramineus) to west nile virus : A potential amplification host in sagebrush-grassland habitat. / Hofmeister, Erik K.; Dusek, Robert J.; Fassbinder-Orth, Carol; Owen, Benjamin; Christian Franson, J.
In: Journal of Wildlife Diseases, Vol. 52, No. 2, 01.04.2016, p. 345-353.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Susceptibility and antibody response of vesper sparrows (Pooecetes gramineus) to west nile virus
T2 - A potential amplification host in sagebrush-grassland habitat
AU - Hofmeister, Erik K.
AU - Dusek, Robert J.
AU - Fassbinder-Orth, Carol
AU - Owen, Benjamin
AU - Christian Franson, J.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - West Nile virus (WNV) spread to the US western plains states in 2003, when a significant mortality event attributed to WNV occurred in Greater Sage-grouse (Centrocercus urophasianus). The role of avian species inhabiting sagebrush in the amplification of WNV in arid and semiarid regions of the North America is unknown. We conducted an experimental WNV challenge study in Vesper Sparrows (Pooecetes gramineus), a species common to sagebrush and grassland habitats found throughout much of North America. We found Vesper Sparrows to be moderately susceptible to WNV, developing viremia considered sufficient to transmit WNV to feeding mosquitoes, but the majority of birds were capable of surviving infection and developing a humoral immune response to the WNV nonstructural 1 and envelope proteins. Despite clearance of viremia, after 6 mo, WNV was detected molecularly in three birds and cultured from one bird. Surviving Vesper Sparrows were resistant to reinfection 6 mo after the initial challenge. Vesper sparrows could play a role in the amplification of WNV in sagebrush habitat and other areas of their range, but rapid clearance of WNV may limit their importance as competent amplification hosts of WNV.
AB - West Nile virus (WNV) spread to the US western plains states in 2003, when a significant mortality event attributed to WNV occurred in Greater Sage-grouse (Centrocercus urophasianus). The role of avian species inhabiting sagebrush in the amplification of WNV in arid and semiarid regions of the North America is unknown. We conducted an experimental WNV challenge study in Vesper Sparrows (Pooecetes gramineus), a species common to sagebrush and grassland habitats found throughout much of North America. We found Vesper Sparrows to be moderately susceptible to WNV, developing viremia considered sufficient to transmit WNV to feeding mosquitoes, but the majority of birds were capable of surviving infection and developing a humoral immune response to the WNV nonstructural 1 and envelope proteins. Despite clearance of viremia, after 6 mo, WNV was detected molecularly in three birds and cultured from one bird. Surviving Vesper Sparrows were resistant to reinfection 6 mo after the initial challenge. Vesper sparrows could play a role in the amplification of WNV in sagebrush habitat and other areas of their range, but rapid clearance of WNV may limit their importance as competent amplification hosts of WNV.
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U2 - 10.7589/2015-06-148
DO - 10.7589/2015-06-148
M3 - Article
VL - 52
SP - 345
EP - 353
JO - Journal of Wildlife Diseases
JF - Journal of Wildlife Diseases
SN - 0090-3558
IS - 2
ER -