Susceptibility and antibody response of vesper sparrows (Pooecetes gramineus) to west nile virus

A potential amplification host in sagebrush-grassland habitat

Erik K. Hofmeister, Robert J. Dusek, Carol Fassbinder-Orth, Benjamin Owen, J. Christian Franson

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

West Nile virus (WNV) spread to the US western plains states in 2003, when a significant mortality event attributed to WNV occurred in Greater Sage-grouse (Centrocercus urophasianus). The role of avian species inhabiting sagebrush in the amplification of WNV in arid and semiarid regions of the North America is unknown. We conducted an experimental WNV challenge study in Vesper Sparrows (Pooecetes gramineus), a species common to sagebrush and grassland habitats found throughout much of North America. We found Vesper Sparrows to be moderately susceptible to WNV, developing viremia considered sufficient to transmit WNV to feeding mosquitoes, but the majority of birds were capable of surviving infection and developing a humoral immune response to the WNV nonstructural 1 and envelope proteins. Despite clearance of viremia, after 6 mo, WNV was detected molecularly in three birds and cultured from one bird. Surviving Vesper Sparrows were resistant to reinfection 6 mo after the initial challenge. Vesper sparrows could play a role in the amplification of WNV in sagebrush habitat and other areas of their range, but rapid clearance of WNV may limit their importance as competent amplification hosts of WNV.

Original languageEnglish
Pages (from-to)345-353
Number of pages9
JournalJournal of Wildlife Diseases
Volume52
Issue number2
DOIs
StatePublished - Apr 1 2016

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West Nile virus
Passeriformes
Artemisia
antibody
amplification
grasslands
grassland
antibodies
habitat
habitats
Centrocercus urophasianus
viremia
bird
birds
immune response
mosquito
semiarid region
arid region
humoral immunity
Culicidae

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Ecology

Cite this

Susceptibility and antibody response of vesper sparrows (Pooecetes gramineus) to west nile virus : A potential amplification host in sagebrush-grassland habitat. / Hofmeister, Erik K.; Dusek, Robert J.; Fassbinder-Orth, Carol; Owen, Benjamin; Christian Franson, J.

In: Journal of Wildlife Diseases, Vol. 52, No. 2, 01.04.2016, p. 345-353.

Research output: Contribution to journalArticle

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