@article{bec112990bdc43d0945c79a0dc48bf7e,
title = "Suspected hereditary nonpolyposis colorectal cancer: International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer (ICG-HNPC) criteria and results of genetic diagnosis",
abstract = "PURPOSE: The aim of this study was to determine the frequency of mutations in the mismatch repair genes in families suspected of having hereditary nonpolyposis colorectal cancer. METHODS: We devised two criteria for families suspected of having hereditary nonpolyposis colorectal cancer (Criteria I and II). Criteria I consist of at least two first-degree relatives affected with colorectal cancer with at least one of the following: development of multiple colorectal tumors including adenomatous polyp, at least one colorectal cancer case diagnosed before the age of 50, and occurrence of a hereditary nonpolyposis colorectal cancer extracolonic cancer (endometrium, urinary tract, small intestine, stomach, hepatobiliary system, or ovary) in family members. Criteria II consist of one colorectal cancer patient with at least one of the following: early age of onset (",
author = "Park, {Jae Gahb} and Vasen, {Hans F.A.} and Park, {Kyu Joo} and Paivi Peltomaki and {Ponz De Leon}, Maurizio and Rodriguez-Bigas, {Miguel A.} and Jan Lubinski and Beck, {Nicholas E.} and Bisgaard, {Marie Luise} and Michiko Miyaki and Wijnen, {Juul Th} and Shozo Baba and Lynch, {Henry T.}",
note = "Funding Information: From the *Korean Hereditary Tumor Registry, Laboratory of Cell Biolog?4 Cancer Research Center, Cancer Research Institute, Seozd National University College of Medicine, Seoul, Korea, the tFoundation for the Detection of Hereditary Tumor, Leiden University Hospital, Leiden, the Netherlands, the fDepartment of Medical Genetics, University of Helsinki, Helsinki, Finland, and the Division of Human Cancer Genelics, Comprehensive Cancer Center, the Ohio State University, Columbus Ohio, the ~Dipartimento di Medicina Interna, Universita di Modena, Modena, Italy, the ]]Division of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, New York, the q[Depa,~ment of Genetics and Pathology., Medical Academ), Szczecin, Poland, the #Cancer and Immunogenetics Laboratory, Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom, the **Danish Hereditary Nonpolyposis Colorectal Cancer Registry, Hvidovre Hospilal, Hvidovre, Denmark, the ttDepartment of Biochemistry, The Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan, the f}Second Department of Surgery, Hamamalsu University School of Medicine, Hamamatsu, Japan, and the ~Department of Preventive Medicine, Creighton University School of Medicine, Omaha, Nebraska",
year = "1999",
month = jun,
doi = "10.1007/BF02236922",
language = "English (US)",
volume = "42",
pages = "710--716",
journal = "Diseases of the Colon and Rectum",
issn = "0012-3706",
publisher = "Lippincott Williams and Wilkins",
number = "6",
}