TY - JOUR
T1 - Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer
T2 - CHEST Guideline and Expert Panel Report
AU - CHEST Expert Cough Panel
AU - CHEST Expert Cough Panel
AU - Molassiotis, Alex
AU - Smith, Jaclyn A.
AU - Mazzone, Peter
AU - Blackhall, Fiona
AU - Irwin, Richard S.
AU - Adams, Todd M.
AU - Altman, Kenneth W.
AU - Barker, Alan F.
AU - Birring, Surinder S.
AU - Blackhall, Fiona
AU - Bolser, Donald C.
AU - Boulet, Louis Philippe
AU - Braman, Sidney S.
AU - Brightling, Christopher
AU - Callahan-Lyon, Priscilla
AU - Canning, Brendan J.
AU - Chang, Anne B.
AU - Cowley, Terrie
AU - Davenport, Paul
AU - Ebihara, Satoru
AU - El Solh, Ali A.
AU - Escalante, Patricio
AU - Field, Stephen K.
AU - Fisher, Dina
AU - French, Cynthia T.
AU - Gibson, Peter
AU - Gold, Philip
AU - Grant, Cameron
AU - Harnden, Anthony
AU - Hill, Adam T.
AU - Irwin, Richard S.
AU - Kahrilas, Peter J.
AU - Keogh, Karina A.
AU - Lai, Kefang
AU - Lane, Andrew P.
AU - Malesker, Mark A.
AU - Mazzone, Peter
AU - Mazzone, Stuart
AU - Murad, M. Hassan
AU - Newcombe, Peter
AU - Nguyen, Huong Q.
AU - Oppenheimer, John
AU - Restrepo, Marcos I.
AU - Rosen, Mark
AU - Rubin, Bruce
AU - Ryu, Jay H.
AU - Smith, Jaclyn
AU - Tarlo, Susan M.
AU - Turmel, Julie
AU - Vertigan, Anne E.
N1 - Publisher Copyright:
© 2017 American College of Chest Physicians
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Background Cough among patients with lung cancer is a common but often undertreated symptom. We used a 2015 Cochrane systematic review, among other sources of evidence, to update the recommendations and suggestions of the American College of Chest Physicians (CHEST) 2006 guideline on this topic. Methods The CHEST methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework were used. The Expert Cough Panel based their recommendations on data from the Cochrane systematic review on the topic, uncontrolled studies, case studies, and the clinical context. Final grading was reached by consensus according to the Delphi method. Results The Cochrane systematic review identified 17 trials of primarily low-quality evidence. Such evidence was related to both nonpharmacologic (cough suppression) and pharmacologic (demulcents, opioids, peripherally acting antitussives, or local anesthetics) treatments, as well as endobronchial brachytherapy. Conclusions Compared with the 2006 CHEST Cough Guideline, the current recommendations and suggestions are more specific and follow a step-up approach to the management of cough among patients with lung cancer, acknowledging the low-quality evidence in the field and the urgent need to develop more effective, evidence-based interventions through high-quality research.
AB - Background Cough among patients with lung cancer is a common but often undertreated symptom. We used a 2015 Cochrane systematic review, among other sources of evidence, to update the recommendations and suggestions of the American College of Chest Physicians (CHEST) 2006 guideline on this topic. Methods The CHEST methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework were used. The Expert Cough Panel based their recommendations on data from the Cochrane systematic review on the topic, uncontrolled studies, case studies, and the clinical context. Final grading was reached by consensus according to the Delphi method. Results The Cochrane systematic review identified 17 trials of primarily low-quality evidence. Such evidence was related to both nonpharmacologic (cough suppression) and pharmacologic (demulcents, opioids, peripherally acting antitussives, or local anesthetics) treatments, as well as endobronchial brachytherapy. Conclusions Compared with the 2006 CHEST Cough Guideline, the current recommendations and suggestions are more specific and follow a step-up approach to the management of cough among patients with lung cancer, acknowledging the low-quality evidence in the field and the urgent need to develop more effective, evidence-based interventions through high-quality research.
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U2 - 10.1016/j.chest.2016.12.028
DO - 10.1016/j.chest.2016.12.028
M3 - Article
C2 - 28108179
AN - SCOPUS:85017156775
VL - 151
SP - 861
EP - 874
JO - Diseases of the chest
JF - Diseases of the chest
SN - 0012-3692
IS - 4
ER -